Cytokines in synovial fluid: II. The presence of tumour necrosis factor and interferon.

Cachectin and tumour necrosis factor as two sides of the same biological coin

1986 • 1,659 citations

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.

1986 • 1,501 citations

Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon.

1986 • 1,439 citations

Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors

1986 • 1,433 citations

Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts.

1985 • 1,240 citations

Characterization of receptors for human tumour necrosis factor and their regulation by γ-interferon

1985 • 896 citations

Stimulation of neutrophils by tumor necrosis factor.

1986 • 847 citations

Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage

1986 • 742 citations

Tumor necrosis factor/cachectin interacts with endothelial cell receptors to induce release of interleukin 1.

1986 • 709 citations

Fibroblast growth enhancing activity of tumor necrosis factor and its relationship to other polypeptide growth factors.

1986 • 674 citations

RHEUMATOID ARTHRITIS: A DISEASE OF T-LYMPHOCYTE/MACROPHAGE IMMUNOREGULATION

1981 • 670 citations

Tumor necrosis factors alpha and beta induce osteoblastic cells to stimulate osteoclastic bone resorption.

1987 • 539 citations

Synergistic interactions between interleukin 1, tumor necrosis factor, and lymphotoxin in bone resorption.

1987 • 527 citations

Immunoregulatory activity of recombinant human tumor necrosis factor (TNF)-alpha: induction of TNF receptors on human T cells and TNF-alpha-mediated enhancement of T cell responses.

1987 • 490 citations

Peripheral blood and synovial fluid monocyte activation in inflammatory arthritis. ii. low levels of synovial fluid and synovial tissue interferon suggest that γgm‐interferon is not the primary macrophage activating factor

1987 • 177 citations

Nonhematopoietic cells selected for resistance to tumor necrosis factor produce tumor necrosis factor.

1986 • 108 citations

Immunohistochemical studies of interleukin‐2 and γ‐interferon in rheumatoid arthritis

1985 • 96 citations

Differential effects of interferon-alpha and interferon-gamma on interleukin 1 secretion by monocytes.

1987 • 95 citations

Immune interferon inhibits collagen synthesis by rheumatoid synovial cells associated wth decreaded levels of the procollagen mRNAs(FEBS 2156)

1985 • 83 citations

Immune interferon in serum and synovial fluid in rheumatoid arthritis and related disorders.

1983 • 79 citations

Preparation and Characterization of Monoclonal Antibodies Directed Against Antigenic Determinants of Recombinant Human Tumour Necrosis Factor (rTNF)

1987 • 63 citations

Differential effects of type I IFN and IFN-gamma on the binding of tumor necrosis factor to receptors in two human cell lines.

1986 • 54 citations

Detection of Hybridomas Secreting Monoclonal Antibodies to Human Gamma Interferon Using a Rapid Screening Technique and Specificity of Certain Monoclonal Antibodies to Gamma Interferon

1984 • 34 citations

Interferon bei chronischer Polyarthritis: Positive Wirkung in der klinischen Prüfung

2008 • 32 citations

Identification, Production, and Characterization of Murine Monoclonal Antibody (LO-22) Recognizing 12 Native Species of Human Alpha Interferon

1984 • 16 citations

Epitope Localization of a Monoclonal Antibody, LO-22, with Broad Specificity for Interferon-α Subtypes

1986 • 9 citations