Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor.

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

PROTEIN-TYROSINE KINASES

1985 • 2,198 citations

The Molecular Genetics of Cancer

1987 • 1,729 citations

SRα Promoter: an Efficient and Versatile Mammalian cDNA Expression System Composed of the Simian Virus 40 Early Promoter and the R-U5 Segment of Human T-Cell Leukemia Virus Type 1 Long Terminal Repeat

1988 • 1,351 citations

Tyrosine Kinase Activity and Transformation Potency of bcr-abl Oncogene Products

1990 • 1,305 citations

Protein Kinase C Contains a Pseudosubstrate Prototope in Its Regulatory Domain

1987 • 1,020 citations

An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity

1984 • 913 citations

Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck

1989 • 671 citations

Characterization of the major protein-tyrosine-phosphatases of human placenta.

1988 • 554 citations

Peptides and Protein Phosphorylation

2018 • 525 citations

Molecular Cloning of Two Types of GAP Complementary DNA from Human Placenta

1988 • 492 citations

Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene

1986 • 489 citations

Structure of the Abelson murine leukemia virus genome and the homologous cellular gene: Studies with cloned viral DNA

1980 • 474 citations

Unique fusion of bcr and c-abl genes in Philadelphia chromosome positive acute lymphoblastic leukemia

1987 • 405 citations

BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias.

1991 • 392 citations

Unique Forms of the abl Tyrosine Kinase Distinguish Ph ¹ -Positive CML from Ph ¹ -Positive ALL

1987 • 344 citations

cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family.

1989 • 313 citations

N-terminal mutations activate the leukemogenic potential of the myristoylated form of c-abl.

1989 • 288 citations

Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products.

1985 • 266 citations

Dephosphorylation or antibody binding to the carboxy terminus stimulates pp60c-src.

1986 • 257 citations

Deletion of an N-terminal regulatory domain of the c-abl tyrosine kinase activates its oncogenic potential.

1989 • 207 citations

A new fused transcript in Philadelphia chromosome positive acute lymphocytic leukaemia

1987 • 201 citations

Amino acid substitutions sufficient to convert the nontransforming p60c-src protein to a transforming protein.

1986 • 171 citations

Cross-linking of T-cell surface molecules CD4 and CD8 stimulates phosphorylation of the lck tyrosine protein kinase at the autophosphorylation site.

1990 • 158 citations

Autoregulation of Enzymes by Pseudosubstrate Prototopes: Myosin Light Chain Kinase

1988 • 152 citations

Alternative forms of the BCR-ABL oncogene have quantitatively different potencies for stimulation of immature lymphoid cells.

1989 • 145 citations

Overlapping cDNA clones define the complete coding region for the P210c-abl gene product associated with chronic myelogenous leukemia cells containing the Philadelphia chromosome.

1986 • 138 citations

Phosphorylation of cellular proteins in Rous sarcoma virus-infected cells: analysis by use of anti-phosphotyrosine antibodies.

1988 • 121 citations

BCR First Exon Sequences Specifically Activate the BCR/ABL Tyrosine Kinase Oncogene of Philadelphia ChromosomePositive Human Leukemias

1991 • 97 citations

In vivo tyrosine phosphorylations of the abelson virus transforming protein are absent in its normal cellular homolog

1982 • 86 citations

Activation of pp60c-src transforming potential by mutations altering the structure of an amino terminal domain containing residues 90-95.

1988 • 85 citations

Dephosphorylation or Antibody Binding to the Carboxy Terminus Stimulates pp60^c-src

1986 • 80 citations

The Hardy–Zuckerman 2-FeSV, a new feline retrovirus with oncogene homology to Abelson-MuLV

1983 • 65 citations

Biochemical characterization of baculovirus-expressed rap1A/Krev-1 and its regulation by GTPase-activating proteins.

1990 • 62 citations

Phosphorylation of Cellular Proteins in Rous Sarcoma Virus-Infected Cells: Analysis by Use of Anti-Phosphotyrosine Antibodies

1988 • 54 citations

Monoclonal antibodies specific for v-abl- and c-abl-encoded molecules

1986 • 50 citations

Detection of c-abl Tyrosine Kinase Activity In Vitro Permits Direct Comparison of Normal and Altered abl Gene Products

1985 • 46 citations

Baculovirus expression of functional P210 BCR-ABL oncogene product.

1989 • 39 citations

Cross-Linking of T-Cell Surface Molecules CD4 and CD8 Stimulates Phosphorylation of the lck Tyrosine Protein Kinase at the Autophosphorylation Site

1990 • 37 citations

Alternative Forms of the BCR-ABL Oncogene Have Quantitatively Different Potencies for Stimulation of Immature Lymphoid Cells

1989 • 30 citations

The 5' noncoding region of the human leukemia-associated oncogene BCR/ABL is a potent inhibitor of in vitro translation.

1989 • 30 citations

Negative regulation of c-abl tyrosine kinase by its variable N-terminal amino acids.

1988 • 23 citations

The 5′ Noncoding Region of the Human Leukemia-Associated Oncogene BCR/ABL Is a Potent Inhibitor of In Vitro Translation

1989 • 11 citations

Biochemical Characterization of Baculovirus-Expressed rap1A/ Krev-1 and Its Regulation by GTPase-Activating Proteins

1990 • 10 citations