Blood Substitutes: 1995 in the Literature

A Trial of Goal-Oriented Hemodynamic Therapy in Critically Ill Patients

1995 • 1,526 citations

The effects of recombinant human hemoglobin on esophageal motor function in humans

1995 • 227 citations

A Heme Oxygenase Product, Presumably Carbon Monoxide, Mediates a Vasodepressor Function in Rats

1995 • 195 citations

Hemoglobin, a newly recognized lipopolysaccharide (LPS)-binding protein that enhances LPS biological activity.

1994 • 136 citations

Endothelial cell heme oxygenase and ferritin induction in rat lung by hemoglobin in vivo

1995 • 115 citations

Blood substitutes : physiological basis of efficacy

1995 • 108 citations

Viral safety of solvent/detergent-treated blood products

1994 • 99 citations

Systemic and subcutaneous microvascular oxygen tension in conscious Syrian golden hamsters

1995 • 95 citations

Transplanting a unique allosteric effect from crocodile into human haemoglobin

1995 • 84 citations

Allosteric transition intermediates modelled by crosslinked haemoglobins

1995 • 84 citations

Current Status of Injectable Oxygen Carriers

1994 • 80 citations

CONTROVERSIES IN SHOCK RESEARCH: HYPERTONIC RESUSCITATION—PROS AND CONS

1995 • 70 citations

Effect of RBC shape and deformability on pulmonary O2 diffusing capacity and resistance to flow in rabbit lungs

1995 • 62 citations

Hemoglobin stimulates mononuclear leukocytes to release interleukin-8 and tumor necrosis factor alpha

1994 • 62 citations

Haemoglobin-based blood substitutes and sepsis

1995 • 60 citations

Immunologic Effects of Blood Transfusion

1995 • 54 citations

Effects of Bacterial Endotoxin on Human Cross-Linked and Native Hemoglobins

1995 • 53 citations

Retracted: Influence of volume replacement with different HES–solutions on microcirculatory blood flow in cardiac surgery

1994 • 51 citations

Blood substitutes — a moving target

1995 • 50 citations

A Theoretical Analysis of Oxygen Transport: A New Strategy for the Design of Hemoglobin-Based Red Cell Substitutes

1995 • 49 citations

Red blood cell substitutes: current status

1995 • 45 citations

Effect of perfluorodecalin as an oxygen carrier on actinorhodin production by Streptomyces coelicolor A3(2)

1995 • 45 citations

Recombinant Human Hemoglobin Inhibits Both Constitutive and Cytokine-Induced Nitric Oxide-Mediated Relaxation of Rabbit Isolated Aortic Rings

1994 • 44 citations

Recombinant Human Hemoglobin Inhibits Both Constitutive and Cytokine-Induced Nitric Oxide-Mediated Relaxation of Rabbit Isolated Aortic Rings

1994 • 43 citations

The D-Helix in Myoglobin and in the .beta. Subunit of Hemoglobin Is Required for the Retention of Heme

1995 • 38 citations

Systemic blood activation during and after autotransfusion

1994 • 37 citations

Microcirculatory Consequences of Blood Substitution with αα-Hemoglobin

1995 • 36 citations

The development of hemoglobin solutions as red cell substitutes: Hemoglobin solutions

1995 • 36 citations

Biomaterial biotechnology using self‐assembled lipid microstructures

1994 • 36 citations

Encapsulation of Hemoglobin in Liposomes

1995 • 35 citations

Clinical Development of Perfluorocarbon-based Emulsions as Red Cell Substitutes

1995 • 31 citations

Vergleichende Untersuchungen zur postoperativen Volumentherapie bei kardiochirurgischen Patienten

1995 • 31 citations

Recombinant Hemoglobins as Blood Substitutes: A Biotechnology Perspective

1995 • 29 citations

Replacement of major surgical blood loss by hypo‐oncotic or conventional plasma substitutes

1995 • 28 citations

Oxygen transport and cardiovascular effects of resuscitation from severe hemorrhagic shock using hemoglobin solutions

1995 • 27 citations

Microencapsulation of hemoglobin in liposomes using a double emulsion, film dehydration/rehydration approach

1994 • 25 citations

Hemoglobin-based oxygen-carrying resuscitation fluids

1995 • 25 citations

A Theoretical Model for Gas Transport and Acid/Base Regulation by Blood Flowing in Microvessels

1994 • 24 citations

Reactions of Nitric Oxide and Hydrogen Peroxide with Hemoglobin‐Based Blood Substitutes

1994 • 23 citations

Effect of an equal volume replacement with 500 mL 6% hydroxyethyl starch on the blood and plasma volume of healthy volunteers.

1995 • 23 citations

Hemoglobin: a newly recognized binding protein for bacterial endotoxins (LPS).

1994 • 20 citations

Redistribution of organ blood flow after hemorrhage and resuscitation in full-term piglets

1994 • 19 citations

Blood Substitutes

1995 • 19 citations

Stability and Toxicity of Hemoglobin Solutions

1995 • 16 citations

The Development of Hemoglobin Solutions as Red Cell Substitutes

1994 • 16 citations

Partial Substitution of Red Blood Cells with Free Hemoglobin Solution Does Not Improve Maximal O2 Uptake of Working In Situ Dog Muscle

1994 • 16 citations

Morphologic and Metabolic Study of the Effect of Oxygenated Perfluorochemical Perfusion on Amputated rabbit limbs

1994 • 16 citations

Perfluorocarbon Emulsions

1995 • 15 citations

An Argument for Colloid Resuscitation for Shock

1994 • 15 citations

The Development of Hemoglobin Solutions as Red Cell Substitutes

1995 • 15 citations

Renal and systemic-hemodynamic response to isovolemic exchange transfusion with hemoglobin cross-linked with bis (3,5-dibromosalicyl) fumarate or albumin.

1995 • 14 citations

Demonstration of the Efficacy of a Therapeutic Agent

1995 • 13 citations

Blood administration, risks, and substitutes.

1995 • 12 citations

Effects of perfluorocarbon exchange transfusion on reducing myocardial infarct size in a primate model of ischemia-reperfusion injury: A prospective, randomized study

1995 • 12 citations

Perfluorocarbon Emulsions: One Approach to Intravenous Artificial Respiratory Gas Transport

1996 • 12 citations

The Development and Use of Oxygen-Carrying Blood Substitutes

1995 • 11 citations

Oxygen Delivery Regulation: Implications for Blood Substitutes

1995 • 10 citations

Autoradiographic determination of regional cerebral blood flow and metabolism in conscious rats after fluid resuscitation from haemorrhage with a haemoglobin-based oxygen carrier

1994 • 10 citations

Small spheres Lead to Big Ideas

1995 • 10 citations

H�moglobinmodifikationen als sauerstofftransportierende Blutersatzmittel

1995 • 8 citations

BLOOD SUBSTITUTES BASED ON MODIFIED HEMOGLOBIN

1994 • 8 citations

Effects of chronic normovolemic anemia on gastric microcirculation and ethanol-induced gastric damage in rats

1994 • 8 citations

Red Cell Substitutes in the Kidney

1995 • 7 citations

Alternatives to regular blood transfusions.

1994 • 6 citations

Divinyl Sulfone Cross-Linked Hyperpolymeric Human Haemoglobin as an Artificial Oxygen Carrier in Anaesthetized Spontaneously Breathing Rats

1994 • 6 citations

Transfusion Alternatives: Impact on Blood Banking Worldwide

1995 • 6 citations

Crocodiles help to develop artificial blood

1995 • 5 citations

Tumor Oxygenation and Radiosensitivity

1995 • 5 citations

Effect of resuscitation solutions on the immune status of dogs in hemorrhagic shock.

1995 • 5 citations

Intraarterial Perfusion of the Hindlimb with Pyridoxalated Hemoglobin Polyoxyethylene Conjugate Solution in Anesthetized Dogs

1995 • 5 citations

Artificial Blood

1995 • 4 citations

[Degree of substitution and volume expanding effect of various medium molecular weight hydroxyethyl starch solutions].

1994 • 4 citations

Combat Casualties, Blood, and Red Blood Cell Substitutes: A Military Perspective in 1995

1995 • 4 citations

The Proton Bohr Factor of Native and Crosslinker Treated Hemoglobins - Its Possible Significance for the Efficacy of Hemoglobin Based Artificial Oxygen Carriers

1994 • 4 citations

[Artificial blood substitutes ].

1994 • 4 citations

Design of Chemically Modified and Recombinant Hemoglobins as Potential Red Cell Substitutes

1995 • 4 citations

A liquid-liquid blood-gas exchange for the treatment of acute respiratory failure: A new blood gas exchange using artificial blood as an oxygen carrier

1994 • 3 citations

Haemoglobin-based blood substitutes: what's on the horizon?

1994 • 3 citations

Effects of artificial blood (FC-43 emulsion) on myocardial energy metabolism in the rat heart-lung preparation

1994 • 3 citations

BLOOD SUBSTITUTES To the Editor

1994 • 2 citations

[Biophysical mechanisms of toxicity of fluorocarbon emulsions].

1994 • 1 citations

[Avoiding risks of unnecessary blood transfusion in surgical patients].

1994 • 1 citations

Administering, documenting, and tracking blood products and volume expanders.

1994 • 1 citations

POSSIBILITIES TO DECREASE THE NEED FOR ALLOGENEIC BLOOD TRANSFUSION DURING SURGERY

1994 • 1 citations

A liquid-liquid blood-gas exchange for the treatment of acute respiratory failure

1996 • 1 citations

Modifizierte Hämoglobinlösungen als künstliche Sauerstoffträger

1994 • 1 citations

Effect of immunomodulatory artificial blood exchange (IABX) on guinea pig-to-rat heart xenografts.

1994 • 1 citations

[Artificial oxygen carriers--perfluorocarbons].

1994 • 1 citations

[Modified hemoglobin solutions as artificial oxygen carriers].

1994 • 1 citations