Phase II trial of cetuximab in the treatment of persistent or recurrent squamous or non-squamous cell carcinoma of the cervix: A Gynecologic Oncology Group study
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References (59)
Regression Models and Life-Tables
1992 • 27,454 citations
Regression Models and Life-Tables
1972 • 27,145 citations
Cancer Statistics, 2010
2010 • 12,557 citations
Cell Signaling by Receptor Tyrosine Kinases
2010 • 7,477 citations
Radiotherapy plus Cetuximab for Squamous-Cell Carcinoma of the Head and Neck
2006 • 4,800 citations
Cell Signaling by Receptor Tyrosine Kinases
2000 • 3,570 citations
Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets
2000 • 2,694 citations
EGFR and cancer prognosis
2001 • 2,068 citations
Phase II Trial of Cetuximab in Patients With Refractory Colorectal Cancer That Expresses the Epidermal Growth Factor Receptor
2004 • 1,709 citations
Randomised study of radical surgery versus radiotherapy for stage Ib-IIa cervical cancer
1997 • 1,599 citations
The EGF receptor family as targets for cancer therapy
2000 • 1,339 citations
Cetuximab Shows Activity in Colorectal Cancer Patients With Tumors That Do Not Express the Epidermal Growth Factor Receptor by Immunohistochemistry
2005 • 1,081 citations
Ligand-Induced, Receptor-Mediated Dimerization and Activation of EGF Receptor
2002 • 972 citations
Open-Label, Uncontrolled, Multicenter Phase II Study to Evaluate the Efficacy and Toxicity of Cetuximab As a Single Agent in Patients With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck Who Failed to Respond to Platinum-Based Therapy
2007 • 937 citations
Single-molecule imaging of EGFR signalling on the surface of living cells
2000 • 884 citations
Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy of solid tumors.
1997 • 841 citations
Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody.
1983 • 792 citations
Phase I Studies of Anti–Epidermal Growth Factor Receptor Chimeric Antibody C225 Alone and in Combination With Cisplatin
2000 • 748 citations
Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer
2008 • 735 citations
KRASMutation Is an Important Predictor of Resistance to Therapy with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non–Small-Cell Lung Cancer
2007 • 597 citations
Randomized Phase III Trial of Cisplatin With or Without Topotecan in Carcinoma of the Uterine Cervix: A Gynecologic Oncology Group Study
2005 • 528 citations
In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody.
2000 • 498 citations
Phase I Study of Anti–Epidermal Growth Factor Receptor Antibody Cetuximab in Combination With Radiation Therapy in Patients With Advanced Head and Neck Cancer
2001 • 479 citations
Biological effects in vitro of monoclonal antibodies to human epidermal growth factor receptors.
1983 • 456 citations
Antitumor Effects of Doxorubicin in Combination With Anti-epidermal Growth Factor Receptor Monoclonal Antibodies
1993 • 422 citations
Epidermal Growth Factor Receptor Tyrosine Kinase as a Target for Anticancer Therapy
2000 • 394 citations
ErbB Receptor-induced Activation of Stat Transcription Factors Is Mediated by Src Tyrosine Kinases
1999 • 365 citations
Enhanced antitumor activity of anti-epidermal growth factor receptor monoclonal antibody IMC-C225 in combination with irinotecan (CPT-11) against human colorectal tumor xenografts.
2002 • 351 citations
Overview of epidermal growth factor receptor biology and its role as a therapeutic target in human neoplasia
2002 • 306 citations
Epidermal growth factor receptor-targeted therapy with C225 and cisplatin in patients with head and neck cancer.
2001 • 299 citations
Antibody-induced epidermal growth factor receptor dimerization mediates inhibition of autocrine proliferation of A431 squamous carcinoma cells.
1994 • 281 citations
Increased EGFR Gene Copy Number Detected by Fluorescent In Situ Hybridization Predicts Outcome in Non–Small-Cell Lung Cancer Patients Treated With Cetuximab and Chemotherapy
2008 • 279 citations
Blockade of epidermal growth factor receptor function by bivalent and monovalent fragments of 225 anti-epidermal growth factor receptor monoclonal antibodies.
1993 • 245 citations
Oncogene alterations in carcinomas of the uterine cervix: overexpression of the epidermal growth factor receptor is associated with poor prognosis.
1999 • 245 citations
Involvement of p27KIP1 in G1 arrest mediated by an anti-epidermal growth factor receptor monoclonal antibody.
1996 • 228 citations
The Role of the Epidermal Growth Factor Receptor Family in Mammary Tumorigenesis and Metastasis
1999 • 190 citations
Epidermal Growth Factor Receptor Family and Chemosensitization
1997 • 176 citations
Antitumor Activity of Combined Blockade of Epidermal Growth Factor Receptor and Protein Kinase A
1996 • 141 citations
Nuclear targeting of Bax during apoptosis in human colorectal cancer cells
1998 • 138 citations
Expression of Epidermal Growth Factor Receptor (EGFR) and Activated EGFR Predict Poor Response to (Chemo)radiation and Survival in Cervical Cancer
2009 • 108 citations
Synchronous Coexpression of Epidermal Growth Factor Receptor and Cyclooxygenase-2 in Carcinomas of the Uterine Cervix
2004 • 108 citations
Effects of concurrent cisplatinum administration during radiotherapy vs. radiotherapy alone on the immune function of patients with cancer of the uterine cervix
2000 • 92 citations
Gynecologic oncology group trials of chemotherapy for metastatic and recurrent cervical cancer
2005 • 88 citations
Overexpression of epidermal growth factor type-1 receptor (EGF-R1) in cervical cancer: Implications for Cetuximab-mediated therapy in recurrent/metastatic disease
2007 • 88 citations
Targeting the epidermal growth factor receptor: a clinical reality.
2001 • 84 citations
Epidermal growth factor receptor-targeted therapy in colorectal cancer
2002 • 75 citations
Inverse correlation between RASSF1A hypermethylation, KRAS and BRAF mutations in cervical adenocarcinoma
2007 • 66 citations
Consistent absence of BRAF mutations in cervical and endometrial cancer despite KRAS mutation status
2005 • 65 citations
New therapeutic agents targeting the epidermal growth factor receptor.
2000 • 63 citations
Epidermal growth factor receptor-targeted therapy in colorectal cancer
2002 • 57 citations
A method for utilizing co-primary efficacy outcome measures to screen regimens for activity in two-stage Phase II clinical trials
2012 • 39 citations
Absence of epidermal growth factor receptor mutations in cervical cancer
2007 • 36 citations
Effect of blood transfusion during radiotherapy on the immune function of patients with cancer of the uterine cervix: role of interleukin-10
2002 • 30 citations
Biological Predictors of Response to Radiotherapy in Head and Neck Cancer: Recent Advances and Emerging Perspectives
2001 • 27 citations
Analysis of chromosomes 3, 7, X and the EGFR gene in uterine cervical cancer progression
2004 • 24 citations
Absence of point mutation in codons 12 and 13 of K-RAS oncogene in HPV-associated high grade dysplasia and squamous cell cervical carcinoma
2003 • 22 citations
Immunocompetent for immunotherapy? A study of the immunocompetence of cervical cancer patients
1995 • 20 citations
“Low-risk” and “High-risk” HPV-infection and K-ras Gene Point Mutations in Human Cervical Cancer
2001 • 15 citations
Cisplatin plus Cetuximab in the Treatment of Recurrent and Persistent Cancers of the Cervix
2010 • 1 citations