Failure of T Cell Receptor V _β Negative Selection in an Athymic Environment

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

1988 • 1,711 citations

Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex

1988 • 1,036 citations

T-cell receptor Vβ use predicts reactivity and tolerance to Mlsa- encoded antigens

1988 • 901 citations

Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors.

1989 • 778 citations

Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor.

1985 • 676 citations

The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens

1988 • 491 citations

Clonal anergy induced in mature Vβ6+ T lymphocytes on immunizing Mls-1b mice with Mls-1a expressing cells

1989 • 462 citations

A T cell receptor Vβ segment that imparts reactivity to a class II major histocompatibility complex product

1987 • 408 citations

The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype.

1984 • 389 citations

T‐Cell Responses to Mls and to Bacterial Proteins that Mimic its Behavior^#

1989 • 337 citations

The MHC molecule I-E is necessary but not sufficient for the clonal deletion of V beta 11-bearing T cells.

1989 • 331 citations

Induction of classical transplantation tolerance in the adult.

1989 • 325 citations

The in vitro generation and sustained culture of nude mouse cytolytic T-lymphocytes.

1979 • 268 citations

Deletion of self-reactive thymocytes occurs at a CD4+8+ precursor stage

1988 • 265 citations

Intrathymic deletion of self-reactive cells prevented by neonatal anti-CD4 antibody treatment

1988 • 197 citations

θ-bearing Lymphocytes in Nude Mice

1973 • 150 citations

Neonatal Thymectomy Results in a Repertoire Enriched in T Cells Deleted in Adult Thymus

1989 • 146 citations

Preferential expression of the T-cell receptor Vβ3 gene by Mlsc reactive T cells

1988 • 123 citations

The T cell receptor Vβ6 domain imparts reactivity to the Mls-1a antigen

1989 • 114 citations

High frequency of T lineage lymphocytes in nude mouse spleen

1974 • 102 citations

Self-tolerance alters T-cell receptor expression in an antigen-specific MHC restricted immune response

1988 • 101 citations

Age-associated increase in expression of the T cell surface markers Thy-1, Lyt-1, and Lyt-2 in congenitally athymic (nu/nu) mice: analysis by flow microfluorometry.

1981 • 100 citations

Thymic Requirement for Clonal Deletion During T Cell Development

1989 • 95 citations

An analysis of T-cell receptor variable region gene expression in major histocompatibility complex disparate mice.

1988 • 91 citations

Abnormal distribution of T cell subsets in athymic mice.

1986 • 89 citations

The composition of the T cell receptor repertoire in nude mice.

1987 • 89 citations

Fc (IgG) receptors on rat basophilic leukemia cells.

1981 • 87 citations

T cell antigen receptor expression in athymic (nu/nu) mice. Evidence for an oligoclonal beta chain repertoire.

1987 • 81 citations

Selective decreases in T cell receptor V beta expression. Decreased expression of specific V beta families is associated with expression of multiple MHC and non-MHC gene products.

1989 • 63 citations

Analysis of CD3 and antigen receptor expression on T cell subpopulations of aged athymic mice

1988 • 43 citations

Athymic nude CD4+8- T cells produce IL-2 but fail to proliferate in response to mitogenic stimuli.

1988 • 25 citations

Impaired clonal expansion in athymic nude CD8+CD4- T cells.

1988 • 22 citations

Variable regions of antibodies to synthetic polypeptides—I. Characterization of an idiotope expressed on antibodies and T-cell factors

1985 • 8 citations