T cell antigen receptor expression in athymic (nu/nu) mice. Evidence for an oligoclonal beta chain repertoire.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Genomic sequencing.

1984 • 8,343 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*

1979 • 1,989 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

1984 • 1,262 citations

Identification of a putative second T-cell receptor

1986 • 980 citations

Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor.

1985 • 676 citations

Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences

1984 • 652 citations

Current concepts of the immunological function of the thymus.

1967 • 577 citations

Developmental regulation of T-cell receptor gene expression

1985 • 522 citations

EXPERIMENTAL STUDIES ON THE DEVELOPMENT OF THE THYMUS

1967 • 504 citations

Thymoma production of T cell growth factor (Interleukin 2).

1980 • 487 citations

A functional T3 molecule associated with a novel heterodimer on the surface of immature human thymocytes

1986 • 430 citations

Mouse T cell antigen receptor: Structure and organization of constant and joining gene segments encoding the β polypeptide

1984 • 407 citations

The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype.

1984 • 389 citations

Murine T-cell receptor mutants with deletions of beta-chain variable region genes.

1986 • 304 citations

Expression of T-cell antigen receptor genes during fetal development in the thymus

1985 • 293 citations

The murine T-cell receptor uses a limited repertoire of expressed Vβ gene segments

1985 • 283 citations

Unusual organization and diversity of T-cell receptor a-chain genes

1985 • 212 citations

The major histocompatibility complex-restricted antigen receptor on T cells: Distribution on thymus and peripheral T cells

1984 • 210 citations

Genomic organization of the genes encoding mouse T-cell receptor α-chain

1985 • 202 citations

Organization and sequences of the variable, joining and constant region genes of the human T-cell receptor α-chain

1985 • 201 citations

Rearrangement of T-cell receptor beta-chain genes during T-cell development.

1985 • 200 citations

Characterization of T Cell Receptor Gamma Chain Expression in a Subset of Murine Thymocytes

1986 • 199 citations

Rearrangement and expression of T cell antigen receptor and gamma genes during thymic development.

1986 • 167 citations

Expression of genes of the T-cell antigen receptor complex in precursor thymocytes

1985 • 135 citations

Athymic mice express a high level of functional γ-chain but greatly reduced levels of α- and β-chain T-cell receptor messages

1986 • 133 citations

Production and characterization of monoclonal anti‐Thy‐1 antibodies that stimulate lymphokine production by cytolytic T cell clones

1985 • 103 citations

Age-associated increase in expression of the T cell surface markers Thy-1, Lyt-1, and Lyt-2 in congenitally athymic (nu/nu) mice: analysis by flow microfluorometry.

1981 • 100 citations

Abnormal distribution of T cell subsets in athymic mice.

1986 • 89 citations

Tγ protein is expressed on murine fetal thymocytes as a disulphide-linked heterodimer

1987 • 84 citations

Requirements for growth of immature thymocytes from fetal and adult mice in vitro

1986 • 78 citations

Vβ gene polymorphism and a major polyclonal T cell receptor idiotype

1985 • 75 citations

Expression of a murine polyclonal T cell receptor marker correlates with the use of specific members of the V beta 8 gene segment subfamily.

1987 • 73 citations

Expression and role of the T cell receptor in early thymocyte differentiation in vitro.

1987 • 66 citations

Growth and differentiation in vitro of the accumulating Lyt-2-/L3T4- subset in lpr mice.

1985 • 64 citations

Differential requirements for the induction of interleukin 2 responsiveness in L3T4+ and Lyt-2+ T cell subsets.

1985 • 45 citations

Light scatter analysis and sorting of cells activated in mixed leukocyte culture

1982 • 41 citations

Cytolytic T lymphocyte precursor cells in congenitally athymic C57BL/6 nu/nu mice: quantitation, enrichment, and specificity.

1981 • 40 citations

N:NIH(S)II-<italic>nu/nu</italic> Mice With Combined Immunodeficiency: A New Model for Human Tumor Heterotransplantation<xref ref-type="fn" rid="fn2">2</xref>

1980 • 40 citations

Biosynthesis of mouse Thy-1 antigen.

1985 • 33 citations

Phenotypic and Functional Characteristics of ‘T-Like’ Cells in Nude Mice

1984 • 28 citations

Frequency and specificity of precursors of interleukin 2-producing cells in nude mice.

1984 • 25 citations

An investigation of T cell receptor gene rearrangement and expression in organ cultures of normal embryonic thymus and Thy‐1⁺ cells of nude mice

1986 • 20 citations

The extent of self-MHC restriction of cytotoxic T cells in nude mice varies from mouse to mouse.

1983 • 15 citations

Ability of Nude Mice to Generate Alloreactive, Xenoreactive and H-2-Restricted Cytotoxic T-Lymphocyte Responses

1984 • 13 citations