Back to search

Neonatal Thymectomy Results in a Repertoire Enriched in T Cells Deleted in Adult Thymus

Data up to Jan 2025

Published1989
Citations146
References29

Total Citations Per Year

Abstract

References (29)

T cell tolerance by clonal elimination in the thymus

1987 • 2,248 citations

Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex

1988 • 1,036 citations

Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention

1988 • 940 citations

Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors.

1989 • 778 citations

Thymus and Reproduction: Sex-Linked Dysgenesia of the Gonad after Neonatal Thymectomy in Mice

1969 • 554 citations

A T cell receptor Vβ segment that imparts reactivity to a class II major histocompatibility complex product

1987 • 408 citations

The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype.

1984 • 389 citations

Effects of Cyclosporine A on T Cell Development and Clonal Deletion

1988 • 354 citations

The MHC molecule I-E is necessary but not sufficient for the clonal deletion of V beta 11-bearing T cells.

1989 • 331 citations

Abnormal differentiation of thymocytes in mice treated with cyclosporin A

1988 • 281 citations

Antigen presenting function of class II MHC expressing pancreatic beta cells

1988 • 255 citations

T cells can distinguish between allogeneic major histocompatibility complex products on different cell types

1988 • 246 citations

Organ-specific autoimmune disease induced in mice by elimination of T cell subsets. V. Neonatal administration of cyclosporin A causes autoimmune disease.

1989 • 197 citations

Spontaneous development of autoimmune thyroiditis in neonatally thymectomized mice.

1976 • 148 citations

T Cell Receptors in Murine Autoimmune Diseases

1989 • 137 citations

STUDIES OF THE ROLE OF THE THYMIC ENVIRONMENT IN THE INDUCTION OF TOLERANCE TO MHC ANTIGENS

1985 • 127 citations

The T-Cell Receptor Repertoire and Autoimmune Diseases

1989 • 124 citations

Intrathymic elimination of Mlsa-reactive (V beta 6+) cells during neonatal tolerance induction to Mlsa-encoded antigens.

1988 • 117 citations

Murine autoimmune oophoritis, epididymoorchitis, and gastritis induced by day 3 thymectomy. Immunopathology.

1987 • 117 citations

The T cell receptor Vβ6 domain imparts reactivity to the Mls-1a antigen

1989 • 114 citations

Minor but not major histocompatibility antigens of thymus epithelium tolerize precursors of cytolytic T cells

1986 • 109 citations

Postnatal disappearance of self-reactive (V beta 6+) cells from the thymus of Mlsa mice. Implications for T cell development and autoimmunity.

1989 • 108 citations

Self-tolerance alters T-cell receptor expression in an antigen-specific MHC restricted immune response

1988 • 101 citations

Autoimmune oophoritis in thymectomized mice: T cell requirement in adoptive cell transfer.

1980 • 95 citations

Experimental production of possible autoimmune castritis followed by macrocytic anemia in athymic nude mice.

1980 • 92 citations

Induction of MHC-restricted specificity and tolerance in the thymus

1986 • 82 citations

Murine autoimmune oophoritis, epididymoorchitis, and gastritis induced by day 3 thymectomy. Autoantibodies.

1987 • 55 citations

The MIs locus: new clues to a lingering mystery

1988 • 32 citations

Properties of the Mls System: A Revised Formulation of Mls Genetics and an Analysis of T‐Cell recognition of Mls Determinants

1989 • 20 citations

Cited By (0)

Loading...
Neonatal Thymectomy Results in a Repertoire Enriched in T Cells Deleted in Adult Thymus (1989) – Science | Metascience Observatory Explorer