Characterization of the Monomeric and Dimeric Forms of Latent and Active Matrix Metalloproteinase-9

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Calculation of protein extinction coefficients from amino acid sequence data

1989 • 5,198 citations

MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

1998 • 1,753 citations

Tissue inhibitors of metalloproteinases: structure, regulation and biological functions.

1997 • 1,510 citations

Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase

1993 • 1,226 citations

SV40-transformed Human Lung Fibroblasts Secrete a 92-kDa Type IV Collagenase Which Is Identical to That Secreted by Normal Human Macrophages

1989 • 1,122 citations

Surface-dependent reactions of the vitamin K-dependent enzyme complexes

1990 • 853 citations

The Behavior and Significance of Slow‐Binding Enzyme Inhibitors

1988 • 828 citations

Matrix metalloproteinases: structures, evolution, and diversification

1998 • 759 citations

A novel coumarin‐labelled peptide for sensitive continuous assays of the matrix metalloproteinases

1992 • 692 citations

Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9.

1992 • 620 citations

Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2.

1989 • 594 citations

Activation of Matrix Metalloproteinase-9 (MMP-9) via a Converging Plasmin/Stromelysin-1 Cascade Enhances Tumor Cell Invasion

1999 • 583 citations

Interaction of 92-kDa type IV collagenase with the tissue inhibitor of metalloproteinases prevents dimerization, complex formation with interstitial collagenase, and activation of the proenzyme with stromelysin.

1992 • 519 citations

Independent expression and cellular processing of Mr 72,000 type IV collagenase and interstitial collagenase in human tumorigenic cell lines.

1990 • 379 citations

Differential Expression of Tissue Inhibitors of Metalloproteinases in the Failing Human Heart

1998 • 376 citations

Activation of progelatinase B (MMP-9) by gelatinase A (MMP-2).

1995 • 324 citations

Expression of matrix metalloproteinases and their inhibitors in aneurysms and normal aorta

1997 • 297 citations

Stromelysin‐1: Three‐dimensional structure of the inhibited catalytic domain and of the C‐truncated proenzyme

1995 • 289 citations

Expression of matrix metalloproteinase 9 (96‐kd gelatinase B) in human rheumatoid arthritis

1996 • 286 citations

Kinetic Analysis of the Binding of Human Matrix Metalloproteinase-2 and -9 to Tissue Inhibitor of Metalloproteinase (TIMP)-1 and TIMP-2

1997 • 279 citations

[30] Tissue inhibitors of matrix metalloendopeptidases

1995 • 263 citations

Design and characterization of a fluorogenic substrate selectively hydrolyzed by stromelysin 1 (matrix metalloproteinase-3).

1994 • 237 citations

Eosinophils as a source of matrix metalloproteinase-9 in asthmatic airway inflammation.

1997 • 230 citations

A 25 kDa α₂‐microglobulin‐related protein is a component of the 125 kDa form of human gelatinase

1992 • 226 citations

Increased Release of Matrix Metalloproteinase-9 in Bronchoalveolar Lavage Fluid and by Alveolar Macrophages of Asthmatics

1997 • 219 citations

Metalloproteinases in tumor progression: the contribution of MMP-9.

1994 • 209 citations

Domain structure of human 72-kDa gelatinase/type IV collagenase. Characterization of proteolytic activity and identification of the tissue inhibitor of metalloproteinase-2 (TIMP-2) binding regions.

1992 • 201 citations

[28] Gelatinases A and B

1995 • 182 citations

Specific, High Affinity Binding of Tissue Inhibitor of Metalloproteinases-4 (TIMP-4) to the COOH-terminal Hemopexin-like Domain of Human Gelatinase A

1997 • 160 citations

Analysis of the role of the COOH-terminal domain in the activation, proteolytic activity, and tissue inhibitor of metalloproteinase interactions of gelatinase B.

1994 • 158 citations

Tumor promoter-stimulated Mr 92,000 gelatinase secreted by normal and malignant human cells: isolation and characterization of the enzyme from HT1080 tumor cells.

1990 • 151 citations

The Helping Hand of Collagenase-3 (MMP-13): 2.7 Å Crystal Structure of its C-terminal Haemopexin-like Domain

1996 • 137 citations

Temporal study of the activity of matrix metalloproteinases and their endogenous inhibitors during wound healing

1996 • 127 citations

Evidence of a role for matrix metalloproteinases in cold preservation injury of the liver in humans and in the rat

1997 • 107 citations

Requirement for matrix metalloproteinase-9 (gelatinase B) expression in metastasis by murine prostate carcinoma.

1998 • 106 citations

[2] Fluorimetric assays of proteolytic enzymes

1995 • 100 citations

The C‐terminal (haemopexin‐like) domain structure of human gelatinase A (MMP2): structural implications for its function

1996 • 94 citations

Phorbol ester-induced cell surface association of matrix metalloproteinase-9 in human MCF10A breast epithelial cells.

1997 • 93 citations

Solution structure of a type 2 module from fibronectin: implications for the structure and function of the gelatin-binding domain

1997 • 92 citations

Matrix metalloproteinase 9 level predicts optimal collagen deposition during early wound repair in humans

1998 • 83 citations

Human gelatinase/type IV procollagenase is a regular plasma component

1989 • 79 citations

Structural characterizations of nonpeptidic thiadiazole inhibitors of matrix metalloproteinases reveal the basis for stromelysin selectivity

1998 • 68 citations

Inhibition of Stromelysin-1 (MMP-3) by P₁‘-Biphenylylethyl Carboxyalkyl Dipeptides

1997 • 65 citations

Developmental expression of MMP‐9 (gelatinase B) mRNA in mouse embryos

1995 • 65 citations

Changes in Matrix Metalloproteinases during the Evolution of Interstitial Renal Fibrosis in a Rat Experimental Model

1998 • 47 citations

Human 92kDa type IV collagenase: Functional analysis of fibronectin and carboxyl-end domains

1993 • 42 citations

A graphical method for extracting rate constants from some enzyme-catalyzed reactions not monitored to completion

1978 • 22 citations