Differential Expression of Tissue Inhibitors of Metalloproteinases in the Failing Human Heart

Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: A report from the studies of left ventricular dysfunction (SOLVD)

1996 • 1,203 citations

Matrix Metalloproteinases and Cardiovascular Disease

1995 • 873 citations

Structural basis of end-stage failure in ischemic cardiomyopathy in humans.

1994 • 583 citations

Molecular Cloning and Characterization of Human Tissue Inhibitor of Metalloproteinase 4

1996 • 547 citations

Matrix metalloproteinase 9 (92-kDa gelatinase/type IV collagenase) from HT 1080 human fibrosarcoma cells. Purification and activation of the precursor and enzymic properties.

1992 • 502 citations

Regulation of collagen degradation in the rat myocardium after infarction

1995 • 469 citations

Remodeling of human myocardial collagen in idiopathic dilated cardiomyopathy. Role of metalloproteinases and pyridinoline cross-links.

1996 • 274 citations

Divergent regulation by growth factors and cytokines of 95 kDa and 72 kDa gelatinases and tissue inhibitors or metalloproteinases-1, -2, and -3 in rabbit aortic smooth muscle cells

1996 • 253 citations

Steps Involved in Activation of the Pro-matrix Metalloproteinase 9 (Progelatinase B)-Tissue Inhibitor of Metalloproteinases-1 Complex by 4-Aminophenylmercuric Acetate and Proteinases

1995 • 189 citations

Preferential Inactivation of Tissue Inhibitor of Metalloproteinases-1 That Is Bound to the Precursor of Matrix Metalloproteinase 9 (Progelatinase B) by Human Neutrophil Elastase

1995 • 188 citations

The effects of cytokines on metalloproteinase inhibitors (TIMP) and collagenase production by human chondrocytes and TIMP production by synovial cells and endothelial cells

1993 • 170 citations

Direct extraction and estimation of collagenase(s) activity by zymography in microquantities of rat myocardium and uterus

1993 • 163 citations

Specific, High Affinity Binding of Tissue Inhibitor of Metalloproteinases-4 (TIMP-4) to the COOH-terminal Hemopexin-like Domain of Human Gelatinase A

1997 • 160 citations

Matrix metalloproteinase activity expression in infarcted, noninfarcted and dilated cardiomyopathic human hearts

1996 • 156 citations

Expression of 92-kD type IV collagenase/gelatinase (gelatinase B) in osteoarthritic cartilage and its induction in normal human articular cartilage by interleukin 1.

1993 • 145 citations

Post-transcriptional Regulation of Extracellular Matrix Metalloproteinase in Human Heart End-stage Failure Secondary to Ischemic Cardiomyopathy

1996 • 141 citations

Characterization of the promoter of the gene encoding human tissue inhibitor of metalloproteinases-2 (TIMP-2)

1994 • 113 citations

Differential gene expression of extracellular matrix components in dilated cardiomyopathy

1996 • 102 citations

Interleukin-1β Inhibits Phospholamban Gene Expression in Cultured Cardiomyocytes

1997 • 93 citations

Co-expression of tissue inhibitor and matrix metalloproteinase in myocardium

1995 • 77 citations

Structure of the human TIMP-3 gene and its cell cycle-regulated promoter

1995 • 64 citations

Molecular Cloning of Mouse Tissue Inhibitor of Metalloproteinases-3 and Its Promoter

1995 • 63 citations

Structural remodelling in heart failure: gelatinase induction.

1994 • 58 citations

Myocardial collagen matrix remodeling and congestive heart failure.

1994 • 27 citations

Interleukin‐1β induction of tissue inhibitor of metalloproteinase (TIMP‐1) is functionally antagonized by prostaglandin E₂ in human synovial fibroblasts

1995 • 20 citations

IL-1β alters the expression of the receptor tyrosine kinase gene r-EphA3 in neonatal rat cardiomyocytes

1998 • 18 citations

Differential effects of IL-1 and TNF alpha on the expression of stromelysin, collagenase and their natural inhibitor, TIMP, in rheumatoid human synovial fibroblasts.

1992 • 17 citations

Human TIMP‐1 Binds to Pro‐M_r 92K GL (Gelatinase B, MMP‐9) through the “Second Disulfide Knot”^a

1994 • 9 citations

The healing wound: A case for extracellular matrix

1996 • 1 citations

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