Requirement for matrix metalloproteinase-9 (gelatinase B) expression in metastasis by murine prostate carcinoma.

Proteolytic remodeling of extracellular matrix

1995 • 1,086 citations

Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9.

1992 • 620 citations

Molecular Cloning and Characterization of Human Tissue Inhibitor of Metalloproteinase 4

1996 • 547 citations

Interaction of 92-kDa type IV collagenase with the tissue inhibitor of metalloproteinases prevents dimerization, complex formation with interstitial collagenase, and activation of the proenzyme with stromelysin.

1992 • 519 citations

Direct evidence linking expression of matrix metalloproteinase 9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells.

1994 • 395 citations

Multistage carcinogenesis induced by ras and myc oncogenes in a reconstituted organ

1989 • 360 citations

Matrix metalloproteinases and tumor invasion: from correlation and causality to the clinic

1996 • 337 citations

Activation of progelatinase B (MMP-9) by gelatinase A (MMP-2).

1995 • 324 citations

High expression of 92-kD type IV collagenase (gelatinase B) in the osteoclast lineage during mouse development

1994 • 286 citations

A new inhibitor of metalloproteinases from chicken: ChIMP-3. A third member of the TIMP family.

1992 • 274 citations

[30] Tissue inhibitors of matrix metalloendopeptidases

1995 • 263 citations

Galectin-3 Is a Novel Substrate for Human Matrix Metalloproteinases-2 and -9

1994 • 259 citations

The activity of the tissue inhibitors of metalloproteinases is regulated by C-terminal domain interactions: A kinetic analysis of the inhibition of gelatinase A

1993 • 237 citations

Preferential inhibition of 72- and 92-kDa gelatinases by tissue inhibitor of metalloproteinases-2

1991 • 227 citations

Expression of metalloproteinase genes in human prostate cancer

1991 • 222 citations

Matrix metalloproteinases and processing of pro-TNF-α

1995 • 222 citations

Inhibition of matrix metalloproteinase 9 expression by a ribozyme blocks metastasis in a rat sarcoma model system.

1996 • 217 citations

c-erbB-2/neu overexpression enhances metastatic potential of human lung cancer cells by induction of metastasis-associated properties

1995 • 210 citations

Mr 92,000 gelatinase release correlates with the metastatic phenotype in transformed rat embryo cells.

1990 • 202 citations

Expression of the metalloproteinase matrilysin in DU-145 cells increases their invasive potential in severe combined immunodeficient mice.

1993 • 201 citations

Genetic change in transforming growth factor beta (TGF-beta) receptor type I gene correlates with insensitivity to TGF-beta 1 in human prostate cancer cells.

1996 • 195 citations

Murine tissue inhibitor of metalloproteinases—4 (Timp—4): cDNA isolation and expression in adult mouse tissues¹

1997 • 192 citations

Construction and identification of cDNA clones for mouse ribosomal proteins: Application for the study of r-protein gene expression

1980 • 187 citations

Harvey ras induction of metastatic potential depends upon oncogene activation and the type of recipient cell.

1985 • 175 citations

Activation of the 92-kDa Gelatinase by Stromelysin and 4-Aminophenylmercuric Acetate

1995 • 166 citations

Analysis of the role of the COOH-terminal domain in the activation, proteolytic activity, and tissue inhibitor of metalloproteinase interactions of gelatinase B.

1994 • 158 citations

In situ hybridization studies of metalloproteinases 2 and 9 and TIMP-1 and TIMP-2 expression in human prostate cancer.

1997 • 156 citations

Binding of tissue inhibitor of metalloproteinases 2 to two distinct sites on human 72-kDa gelatinase. Identification of a stabilization site.

1991 • 138 citations

Degradation of entactin by matrix metalloproteinases. Susceptibility to matrilysin and identification of cleavage sites.

1993 • 138 citations

Role of the 21-kDa protein TIMP-3 in oncogenic transformation of cultured chicken embryo fibroblasts.

1992 • 137 citations

Protease inhibitors: Role and potential therapeutic use in human cancer

1994 • 134 citations

Evidence for post-transcriptional regulation of cyclin B1 mRNA in the cell cycle and following irradiation in HeLa cells.

1995 • 132 citations

Matrix metalloproteinase 9 expression in primary human prostatic adenocarcinoma and benign prostatic hyperplasia

1994 • 130 citations

Expression of transforming growth factor-beta 1 in prostate cancer.

1994 • 128 citations

Loss of p53 function leads to metastasis in ras+myc-initiated mouse prostate cancer.

1995 • 114 citations

Proteolytic and non-proteolytic activation of human neutrophil progelatinase B

1995 • 102 citations

Activation of the 92 kDa type IV collagenase by tissue kallikrein

1993 • 95 citations

Phorbol ester-induced cell surface association of matrix metalloproteinase-9 in human MCF10A breast epithelial cells.

1997 • 93 citations

Molecular Cloning and Expression of the Mouse 105-kDa Gelatinase cDNA

1993 • 91 citations

Transforming growth factor beta1 stimulates contrasting responses in metastatic versus primary mouse prostate cancer-derived cell lines in vitro.

1996 • 83 citations

Elevated Transforming Growth Factor-β 1 and β3 mRNA Levels are Associated withras+myc-induced Carcinomas in Reconstituted Mouse Prostate: Evidence for a Paracrine Role during Progression

1991 • 62 citations

Lack of the latent transforming growth factor beta binding protein in malignant, but not benign prostatic tissue.

1993 • 61 citations

Increased matrix metalloproteinase-9 secretion in short-term tissue cultures of prostatic tumor cells

1996 • 51 citations

Human 92kDa type IV collagenase: Functional analysis of fibronectin and carboxyl-end domains

1993 • 42 citations

Transforming growth factor beta I expression in benign and malignant prostatic tumors

1994 • 40 citations

Cell-mediated degradation of type IV collagen and gelatin films is dependent on the activation of matrix metalloproteinases

1992 • 34 citations

Differential expression of transforming growth factor-?1 and ?3 as well as C-FOS mRNA in normal human prostate, benign prostatic hyperplasia and prostatic cancer

1994 • 31 citations

The effect of E1A transfection on MMP‐9 expression and metastatic potential

1995 • 29 citations

Androgen sensitivity and gene expression in ras + myc-induced mouse prostate carcinomas

1992 • 13 citations