Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis

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2001 • 133,517 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Mutations affecting segment number and polarity in Drosophila

1980 • 4,280 citations

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

1983 • 2,456 citations

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

A C-terminal signal prevents secretion of luminal ER proteins

1987 • 2,189 citations

The Drosophila homology of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless

1987 • 906 citations

Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

1988 • 745 citations

Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo

1987 • 578 citations

A whole-mount immunocytochemical analysis of the expression of the intermediate filament protein vimentin in Xenopus

1989 • 441 citations

Molecular cloning of sequences from wingless , a segment polarity gene in Drosophila : the spatial distribution of a transcript in embryos

1987 • 437 citations

Two-tiered regulation of spatially patterned engrailed gene expression during Drosophila embryogenesis

1988 • 383 citations

Expression of the proto-oncogene int-1 is restricted to postmeiotic male germ cells and the neural tube of mid-gestational embryos

1987 • 261 citations

Structure and nucleotide sequence of the putative mammary oncogene int-1; proviral insertions leave the protein-encoding domain intact

1984 • 222 citations

Two proto-oncogenes implicated in mammary carcinogenesis, int-1 and int-2, are independently regulated during mouse development.

1986 • 211 citations

A retrovirus vector expressing the putative mammary oncogene int-1 causes partial transformation of a mammary epithelial cell line

1986 • 189 citations

The development of wingless, a homeotic mutation of Drosophila

1977 • 185 citations

Precursor of egg white lysozyme. Amino acid sequence of an NH2-terminal extension.

1977 • 155 citations

The int genes in mammary tumorigenesis and in normal development

1988 • 117 citations

Transfection of the int-1 mammary oncogene in cuboidal RAC mammary cell line results in morphological transformation and tumorigenicity.

1987 • 116 citations

Microinjection of synthetic Xhox-1A homeobox mRNA disrupts somite formation in developing Xenopus embryos

1988 • 111 citations

Nucleotide sequence and expression in vitro of cDNA derived from mRNA of int-1, a provirally activated mouse mammary oncogene.

1985 • 110 citations

Monoclonal antibodies to the cells of a regenerating limb

1985 • 103 citations

Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless.

1988 • 95 citations

The activation of cellular oncogenes by retroviral insertion

1986 • 87 citations

Identification of protein products encoded by the proto-oncogene int-1.

1987 • 80 citations

Antisence RNA inhibits expression of membrane skeleton protein 4.1 during embryonic development of xenopus

1988 • 79 citations

Cell lineage labels and region-specific markers in the analysis of inductive interactions

1985 • 76 citations

Isolation of theXenopusbomolog ofint-1/winglessand expression during neurula stages of early development

1989 • 73 citations

Effects of altered expression of the neural cell adhesion molecule, N-CAM, on early neural development in Xenopus embryos

1988 • 65 citations

Anion transporter: highly cell-type-specific expression of distinct polypeptides and transcripts in erythroid and nonerythroid cells.

1985 • 61 citations

Properties of the primary organization field in the embryo of Xenopus laevis : II. Positional information for axial organization in embryos with two head organizers

1972 • 55 citations

Changes in the expression of alpha-fodrin during embryonic development of Xenopus laevis.

1987 • 50 citations

int-1--a proto-oncogene involved in cell signalling.

1989 • 46 citations