A Monoclonal Antibody to the α Subunit of G _k Blocks Muscarinic Activation of Atrial K ⁺ Channels

The βγ subunits of GTP-binding proteins activate the muscarinic K+ channel in heart

1987 • 1,186 citations

GTP-binding proteins couple cardiac muscarinic receptors to a K channel

1985 • 868 citations

Roles of G protein subunits in transmembrane signalling

1988 • 794 citations

Rhodopsin content in the outer segment membranes of bovine and frog retinal rods

1974 • 730 citations

A G Protein Directly Regulates Mammalian Cardiac Calcium Channels

1987 • 551 citations

Uncoupling of cardiac muscarinic and β-adrenergic receptors from ion channels by a guanine nucleotide analogue

1985 • 527 citations

Site of G Protein Binding to Rhodopsin Mapped with Synthetic Peptides from the α Subunit

1988 • 491 citations

Acetylcholine activation of single muscarinic K+ channels in isolated pacemaker cells of the mammalian heart

1983 • 471 citations

Direct Activation of Mammalian Atrial Muscarinic Potassium Channels by GTP Regulatory Protein G _k

1987 • 441 citations

Mode of regulation of the ACh-sensitive K-channel by the muscarinic receptor in rabbit atrial cells

1984 • 436 citations

The α Subunit of the GTP Binding Protein G _k Opens Atrial Potassium Channels

1987 • 317 citations

Reconstitution of resolved muscarinic cholinergic receptors with purified GTP-binding proteins.

1985 • 314 citations

Characterization of bovine rod outer segment G-protein.

1982 • 281 citations

The stimulatory G protein of adenylyl cyclase, Gs, also stimulates dihydropyridine-sensitive Ca2+ channels. Evidence for direct regulation independent of phosphorylation by cAMP-dependent protein kinase or stimulation by a dihydropyridine agonist.

1988 • 273 citations

ATP mediates rapid reversal of cyclic GMP phosphodiesterase activation in visual receptor membranes

1980 • 251 citations

Mammalian .beta.2-adrenergic receptor: reconstitution of functional interactions between pure receptor and pure stimulatory nucleotide binding protein of the adenylate cyclase system

1984 • 249 citations

Ns and Ni, the stimulatory and inhibitory regulatory components of adenylyl cyclases. Purification of the human erythrocyte proteins without the use of activating regulatory ligands.

1984 • 242 citations

Functional reconstitution of the alpha 2-adrenergic receptor with guanine nucleotide regulatory proteins in phospholipid vesicles.

1986 • 199 citations

Reconstitution of Somatostatin and Muscarinic Receptor Mediated Stimulation of K⁺Channels by Isolated G_KProtein in Clonal Rat Anterior Pituitary Cell Membranes *

1987 • 188 citations

Distinct forms of the beta subunit of GTP-binding regulatory proteins identified by molecular cloning.

1987 • 185 citations

Rhodopsin-enhanced GTPase activity of the inhibitory GTP-binding protein of adenylate cyclase.

1984 • 166 citations

Atriopeptin II decreases cytosolic free Ca in cultured vascular smooth muscle cells

1986 • 135 citations

Characterization of transducin from bovine retinal rod outer segments. Participation of the amino-terminal region of T alpha in subunit interaction.

1987 • 131 citations

Pertussis toxin treatment blocks hyperpolarization by muscarinic agonists in chick atrium.

1985 • 71 citations

Alpha-subunit of Gs directly activates cardiac calcium channels in lipid bilayers

1988 • 70 citations

Mechanism of action of monoclonal antibodies that block the light activation of the guanyl nucleotide-binding protein, transducin.

1987 • 69 citations

Topographic analysis of antigenic determinants recognized by monoclonal antibodies to the photoreceptor guanyl nucleotide-binding protein, transducin.

1987 • 68 citations

Inhibition of bovine rod outer segment GTPase by Bordetella pertussis toxin.

1984 • 57 citations

Pertussis toxin-insensitive phosphoinositide hydrolysis, membrane depolarization, and positive inotropic effect of carbachol in chick atria.

1987 • 55 citations

Hormonal regulation of pituitary GH₃ cell K⁺ channels by G_k is mediated by its α‐subunit

1987 • 55 citations

Physical and functional association of follitropin receptors with cholera toxin-sensitive guanine nucleotide-binding protein.

1987 • 53 citations

Regulation of glucagon receptor binding. Lack of effect of Mg and preferential role for GDP.

1985 • 48 citations

Preparation and characterization of monoclonal antibodies to several frog rod outer segment proteins.

1984 • 44 citations

[50] Transducin and the cyclic GMP phosphodiesterase of retinal rod outer segments

1983 • 33 citations

Direct Coupling of G Proteins to Ionic Channels

1988 • 15 citations