Pre-clinical evaluation of probes to detect t(8;21) AML minimal residual disease by fluorescence in situ hybridization

Methods in yeast genetics

1979 • 7,824 citations

Methods in Yeast Genetics

1988 • 4,905 citations

Molecular cloning (2nd Ed)

1989 • 1,191 citations

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1.

1991 • 897 citations

Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt

1992 • 582 citations

Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt

1992 • 494 citations

Detection of minimal residual disease in acute leukemia: methodologic advances and clinical significance [see comments]

1995 • 452 citations

A YAC contig map of the human genome.

1995 • 333 citations

Persistence of the 8;21 translocation in patients with acute myeloid leukemia type M2 in long-term remission

1993 • 297 citations

Establishment of a human acute myeloid leukemia cell line (Kasumi-1) with 8;21 chromosome translocation

1991 • 288 citations

Detection of DNA rearrangements in the AML1 and ETO loci and of an AML1/ETO fusion mRNA in patients with t(8;21) acute myeloid leukemia

1993 • 193 citations

An AML1/ETO fusion transcript is consistently detected by RNA-based polymerase chain reaction in acute myelogenous leukemia containing the (8;21)(q22;q22) translocation

1993 • 174 citations

Persistence of the AML1/ETO fusion transcript in patients treated with allogeneic bone marrow transplantation for t(8;21) leukemia

1996 • 157 citations

Polymerase chain reaction in the detection of micrometastases and circulating tumor cells

1996 • 149 citations

Quantitative acute leukemia cytogenetics

1992 • 126 citations

Simultaneous localization of cosmids and chromosome R-banding by fluorescence microscopy: application to regional mapping of human chromosome 11.

1990 • 106 citations

Monitoring of minimal residual disease by quantitative reverse transcriptase-polymerase chain reaction for AML1-MTG8 transcripts in AML-M2 with t(8; 21)

1996 • 93 citations

ETO and AML1 phosphoproteins are expressed in CD34+ hematopoietic progenitors: implications for t(8;21) leukemogenesis and monitoring residual disease

1996 • 88 citations

Expression of AML1-ETO fusion transcripts and detection of minimal residual disease in t(8;21)-positive acute myeloid leukemia.

1993 • 83 citations

Design and validation of DNA probe sets for a comprehensive interphase cytogenetic analysis of acute myeloid leukemia

1996 • 83 citations

The 8;21 chromosome translocation in acute myeloid leukemia is always detectable by molecular analysis using AML1

1993 • 71 citations

Consistent disruption of the AML1 gene occurs within a single intron in the t(8;21) chromosomal translocation.

1992 • 70 citations

Detecting genetic changes in human tumor cells: have scientists "gone fishing?" [editorial] [see comments]

1993 • 57 citations

Detection of AML1/ETO fusion transcript as a tool for diagnosing t(8;21) positive acute myelogenous leukemia.

1994 • 50 citations

Detection of t(8;21) by reverse transcriptase polymerase chain reaction in patients in remission of acute myeloid leukaemia type M2 after chemotherapy or bone marrow transplantation

1994 • 48 citations

SERIAL QUANTIFICATION OF MINIMAL RESIDUAL DISEASE OF t(8;21) ACUTE MYELOGENOUS LEUKAEMIA WITH RT‐COMPETITIVE PCR ASSAY

1996 • 42 citations

Interphase cytogenetics of the t(8;21)(q22;q22) associated with acute myelogenous leukemia by two-color fluorescence in situ hybridization

1995 • 39 citations

Translocation breakpoints are clustered on both chromosome 8 and chromosome 21 in the t(8;21) of acute myeloid leukemia

1993 • 35 citations

AML-1 gene rearrangement and AML-1-ETO gene expression as molecular markers of acute myeloblastic leukemia with t(8;21).

1994 • 27 citations

Polyclonal haemopoieses associated with long‐term persistence of the AML1‐ETO transcript in patients with FAB M2 acute myeloid leukaemia in continous clinical remission

1995 • 26 citations

Isolation and regional mapping of NotI and EagI clones from human chromosome 21

1991 • 13 citations