Design and validation of DNA probe sets for a comprehensive interphase cytogenetic analysis of acute myeloid leukemia

Cloning of Large Segments of Exogenous DNA into Yeast by Means of Artificial Chromosome Vectors

1987 • 1,517 citations

Fusion Between Transcription Factor CBFβ/PEBP2β and a Myosin Heavy Chain in Acute Myeloid Leukemia

1993 • 760 citations

p53 gene deletion predicts for poor survival and non-response to therapy with purine analogs in chronic B-cell leukemias

1995 • 749 citations

Molecular Analysis of Acute Promyelocytic Leukemia Breakpoint Cluster Region on Chromosome 17

1990 • 650 citations

Rearrangement of the MLL Gene in Acute Lymphoblastic and Acute Myeloid Leukemias with 11q23 Chromosomal Translocations

1993 • 523 citations

A first-generation physical map of the human genome

1993 • 446 citations

The Human Y Chromosome: Overlapping DNA Clones Spanning the Euchromatic Region

1992 • 394 citations

Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: diagnosis of trisomy 18 with probe L1.84

1986 • 380 citations

Detection of bcr - abl Fusion in Chronic Myelogeneous Leukemia by in Situ Hybridization

1990 • 371 citations

Prognostic impact of cytogenetic abnormalities in patients with de novo acute nonlymphocytic leukemia

1989 • 294 citations

The 5q-syndrome

1994 • 256 citations

Report of the committee on chromosome changes in neoplasia

1990 • 249 citations

Mapping chromosome band 11q23 in human acute leukemia with biotinylated probes: identification of 11q23 translocation breakpoints with a yeast artificial chromosome.

1990 • 247 citations

Prediction of the Risk of Hereditary Retinoblastoma, Using DNA Polymorphisms within the Retinoblastoma Gene

1988 • 242 citations

Molecular pathogenesis of the chromosome 16 inversion in the M4Eo subtype of acute myeloid leukemia [see comments]

1995 • 220 citations

The Molecular Basis of Leukemia

1994 • 210 citations

Fluorescence in situ hybridization of YAC clones after Alu-PCR amplification

1992 • 209 citations

Partial tandem duplication of ALL1 as a recurrent molecular defect in acute myeloid leukemia with trisomy 11.

1996 • 193 citations

Detection of the Philadelphia chromosome in interphase nuclei

1990 • 185 citations

The clinical significance of karyotype in acute myelogenous leukemia

1989 • 174 citations

Detection of fusion transcripts generated by the inversion 16 chromosome in acute myelogenous leukemia

1994 • 168 citations

Detection of chimeric BCR-ABL genes on bone marrow samples and blood smears in chronic myeloid and acute lymphoblastic leukemia by in situ hybridization

1994 • 144 citations

High frequency of monoallelic retinoblastoma gene deletion in B-cell chronic lymphoid leukemia shown by interphase cytogenetics

1993 • 127 citations

The Reference Library System — sharing biological material and experimental data

1994 • 115 citations

Heterogeneity in CBF beta/MYH11 fusion messages encoded by the inv(16)(p13q22) and the t(16;16)(p13;q22) in acute myelogenous leukemia

1995 • 106 citations

Incidence and characterization of MLL gene (11q23) rearrangements in acute myeloid leukemia M1 and M5

1996 • 103 citations

[22] Detection of chromosomal aberrations by means of molecular cytogenetics: Painting of chromosomes and chromosomal subregions and comparative genomic hybridization

1995 • 94 citations

Molecular characterization of 16p deletions associated with inversion 16 defines the critical fusion for leukemogenesis

1995 • 91 citations

Fluorescence in situ hybridization mapping of translocations and deletions involving the short arm of human chromosome 12 in malignant hematologic diseases

1994 • 90 citations

Correlation between cell morphology and expression of the AML1/ETO chimeric transcript in patients with acute myeloid leukemia without the t(8;21).

1994 • 85 citations

Detection of minimal residual disease in acute myelomonocytic leukemia with abnormal marrow eosinophils by nested polymerase chain reaction with allele specific amplification

1994 • 84 citations

Chromosome abnormalities in acute nonlymphocytic leukemia: clinical and biologic significance.

1987 • 84 citations

Interstitial insertion of retinoic acid receptor-alpha gene in acute promyelocytic leukemia with normal chromosomes 15 and 17

1994 • 83 citations

Metaphase and interphase cytogenetics with Alu-PCR-amplified yeast artificial chromosome clones containing the BCR gene and the protooncogenes c-raf-1, c-fms, and c-erbB-2.

1992 • 80 citations

Heterogeneity of breakpoints of 11q23 rearrangements in hematologic malignancies identified with fluorescence in situ hybridization

1993 • 77 citations

Rapid detection of chromosome 16 inversion in acute nonlymphocytic leukemia, subtype M4: regional localization of the breakpoint in 16p

1990 • 71 citations

RT-PCR diagnosis of patients with acute nonlymphocytic leukemia and inv(16)(p13q22) and identification of new alternative splicing in CBFB- MYH11 transcripts

1995 • 67 citations

Sequence-independent amplification and labeling of yeast artificial chromosomes for fluorescence in situ hybridization

1994 • 61 citations

Chromosomal loss and deletion are the most common mechanisms for loss of heterozygosity from chromosomes 5 and 7 in malignant myeloid disorders

1992 • 61 citations

Detecting genetic changes in human tumor cells: have scientists "gone fishing?" [editorial] [see comments]

1993 • 57 citations

CCD microscopy and image analysis of cells and chromosomes stained by fluorescence in situ hybridization

1995 • 52 citations

Report of the First International Workshop on Human Chromosome 7 Mapping 1993

1994 • 45 citations

Interphase cytogenetics of the t(8;21)(q22;q22) associated with acute myelogenous leukemia by two-color fluorescence in situ hybridization

1995 • 39 citations

Hunting 11q23 deletions with fluorescence in situ hybridization (FISH).

1994 • 35 citations

3.6-Mb Genomic and YAC Physical Map of the Down Syndrome Chromosome Region on Chromosome 21

1994 • 31 citations

A YAC clone map spanning 7.5 megabases of human chromosome band Xq28

1994 • 27 citations

A 530kb YAC contig tightly linked to the Friedreich ataxia locus contains five CpG clusters and a new highly polymorphic microsatellite

1992 • 17 citations

Molecular analysis of the Mono Mac 6 cell line: detection of an MLL-AF9 fusion transcript [letter; comment]

1995 • 16 citations

Molecular cloning and analysis of chromosome band 11q23 involved in leukaemia‐associated translocations

1992 • 12 citations

t(8;21)(q22;q22)

2010 • 5 citations