Herp, a New Ubiquitin-like Membrane Protein Induced by Endoplasmic Reticulum Stress

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

1987 • 5,139 citations

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

1999 • 3,119 citations

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

1999 • 2,237 citations

A C-terminal signal prevents secretion of luminal ER proteins

1987 • 2,189 citations

Homocysteine and Cardiovascular Disease

1998 • 2,177 citations

Mammalian Transcription Factor ATF6 Is Synthesized as a Transmembrane Protein and Activated by Proteolysis in Response to Endoplasmic Reticulum Stress

1999 • 1,954 citations

SOSUI: classification and secondary structure prediction system for membrane proteins.

1998 • 1,907 citations

Identification of the cis-Acting Endoplasmic Reticulum Stress Response Element Responsible for Transcriptional Induction of Mammalian Glucose-regulated Proteins

1998 • 1,216 citations

Setting the Standards: Quality Control in the Secretory Pathway

1999 • 1,198 citations

Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

1993 • 1,197 citations

The I.M.A.G.E. Consortium: An Integrated Molecular Analysis of Genomes and Their Expression

1996 • 1,132 citations

The PROSITE database, its status in 1999

1999 • 1,109 citations

A Novel Mechanism for Regulating Activity of a Transcription Factor That Controls the Unfolded Protein Response

1996 • 1,017 citations

Tripartite Management of Unfolded Proteins in the Endoplasmic Reticulum

2000 • 917 citations

A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells

1998 • 888 citations

A transmembrane protein with a cdc2+CDC28-related kinase activity is required for signaling from the ER to the nucleus

1993 • 814 citations

Control of Protein Exit from the Endoplasmic Reticulum

1989 • 794 citations

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

1998 • 782 citations

Coatomer Interaction with Di-Lysine Endoplasmic Reticulum Retention Motifs

1994 • 574 citations

Internal initiation of translation mediated by the 5′ leader of a cellular mRNA

1991 • 554 citations

ER Quality Control: The Cytoplasmic Connection

1997 • 528 citations

Rad23 links DNA repair to the ubiquitin/proteasome pathway

1998 • 452 citations

Signalling from endoplasmic reticulum to nucleus: transcription factor with a basic‐leucine zipper motif is required for the unfolded protein‐response pathway

1996 • 363 citations

Prediction of the Coding Sequences of Unidentified Human Genes. I. The Coding Sequences of 40 New Genes (KIAA0001-KIAA0040) Deduced by Analysis of Randomly Sampled cDNA Clones from Human Immature Myeloid Cell Line KG-1 (Supplement)

1994 • 362 citations

Homocysteine-respondent Genes in Vascular Endothelial Cells Identified by Differential Display Analysis

1996 • 360 citations

Homocysteine-Induced Endoplasmic Reticulum Stress and Growth Arrest Leads to Specific Changes in Gene Expression in Human Vascular Endothelial Cells

1999 • 347 citations

gp25L/emp24/p24 Protein Family Members of the cis-Golgi Network Bind Both COP I and II Coatomer

1998 • 335 citations

Bimodal Interaction of Coatomer with the p24 Family of Putative Cargo Receptors

1996 • 333 citations

Elongin (SIII): A Multisubunit Regulator of Elongation by RNA Polymerase II

1995 • 320 citations

Endoplasmic Reticulum Stress-induced mRNA Splicing Permits Synthesis of Transcription Factor Hac1p/Ern4p That Activates the Unfolded Protein Response

1997 • 283 citations

Interaction of hHR23 with S5a

1999 • 261 citations

Prediction of the Coding Sequences of Unidentified Human Genes. I. The Coding Sequences of 40 New Genes (KIAA0001-KIAA0040) Deduced by Analysis of Randomly Sampled cDNA Clones from Human Immature Myeloid Cell Line KG-1

1994 • 240 citations

Characterization of the stress-inducing effects of homocysteine

1998 • 231 citations

The mammalian endoplasmic reticulum stress response element consists of an evolutionarily conserved tripartite structure and interacts with a novel stress-inducible complex

1999 • 231 citations

Role of potentially charged transmembrane residues in targeting proteins for retention and degradation within the endoplasmic reticulum.

1991 • 215 citations

Translational attenuation mediated by an mRNA intron

1997 • 183 citations

mRNA splicing-mediated C-terminal replacement of transcription factor Hac1p is required for efficient activation of the unfolded protein response

2000 • 181 citations

Homocyst(e)ine: an important risk factor for atherosclerotic vascular disease

1997 • 149 citations

Palindrome with Spacer of One Nucleotide Is Characteristic of the cis-Acting Unfolded Protein Response Element inSaccharomyces cerevisiae

1998 • 146 citations

Endoplasmic reticulum localization of Sec12p is achieved by two mechanisms: Rer1p-dependent retrieval that requires the transmembrane domain and Rer1p-independent retention that involves the cytoplasmic domain.

1996 • 136 citations

The Ligation Systems for Ubiquitin and Ubiquitin-like Proteins

1998 • 97 citations

New COP1-binding motifs involved in ER retrieval

1998 • 81 citations

Uncleaved signals for glycosylphosphatidylinositol anchoring cause retention of precursor proteins in the endoplasmic reticulum

1993 • 75 citations

Mechanisms of thrombosis in hyperhomocysteinemia

1998 • 68 citations

Activation Peptide of Human Factor IX Has Oligosaccharides O-Glycosidically Linked to Threonine Residues at 159 and 169

1994 • 52 citations

Molecular biology of circulatory shock. Part II. Expression of four groups of hepatic genes is enhanced after resuscitation from cardiogenic shock.

1990 • 49 citations

The novel MMS‐inducible gene Mif1/KIAA0025 is a target of the unfolded protein response pathway

2000 • 41 citations

Protein regulation: Tag wrestling with relatives of ubiquitin

1998 • 36 citations

The Elongin B Ubiquitin Homology Domain

1999 • 16 citations