Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes

Genomic imprinting: parental influence on the genome

2001 • 2,253 citations

The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus

1991 • 904 citations

Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation

2001 • 687 citations

Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2

1998 • 641 citations

Imprinted expression of the Igf2r gene depends on an intronic CpG island

1997 • 578 citations

Mouse Mutants Lacking the Type 2 IGF Receptor (IGF2R) Are Rescued from Perinatal Lethality inIgf2andIgf1rNull Backgrounds

1996 • 479 citations

A maternally methylated CpG island in KvLQT1 is associated with an antisense paternal transcript and loss of imprinting in Beckwith–Wiedemann syndrome

1999 • 405 citations

Insulators and Boundaries: Versatile Regulatory Elements in the Eukaryotic Genome

2001 • 386 citations

What If There Are Only 30,000 Human Genes?

2001 • 339 citations

A mouse model for Prader-Willi syndrome imprinting-centre mutations

1998 • 298 citations

The imprinted antisense RNA at the Igf2r locus overlaps but does not imprint Mas1

2000 • 280 citations

Imprinting-Mutation Mechanisms in Prader-Willi Syndrome

1999 • 276 citations

Multiple Mechanisms Regulate Imprinting of the Mouse Distal Chromosome 7 Gene Cluster

1998 • 245 citations

Impaired Activity of the Extraneuronal Monoamine Transporter System Known as Uptake-2 in Orct3/Slc22a3-Deficient Mice

2001 • 193 citations

Disruption of primary imprinting during oocyte growth leads to the modified expression of imprinted genes during embryogenesis

1998 • 187 citations

Targeted disruption of the human LIT1 locus defines a putative imprinting control element playing an essential role in Beckwith-Wiedemann syndrome

2000 • 178 citations

Mosaic and polymorphic imprinting of the WT1 gene in humans

1994 • 172 citations

Asynchronous replication of imprinted genes is established in the gametes and maintained during development

1999 • 170 citations

An imprinted transcript, antisense to Nesp, adds complexity to the cluster of imprinted genes at the mouse Gnas locus

2000 • 160 citations

Developmental potential of mouse primordial germ cells

1999 • 147 citations

Sequence and functional comparison in the Beckwith-Wiedemann region: implications for a novel imprinting centre and extended imprinting

2000 • 140 citations

Non-imprinted Igf2r expression decreases growth and rescues the Tme mutation in mice

2001 • 130 citations

Sequence conservation and variability of imprinting in the Beckwith-Wiedemann syndrome gene cluster in human and mouse

2000 • 128 citations

Cloning of the Mouse and Human Solute Carrier 22a3 (Slc22a3/SLC22A3) Identifies a Conserved Cluster of Three Organic Cation Transporters on Mouse Chromosome 17 and Human 6q26–q27

1999 • 115 citations

Genetic analysis of genomic imprinting: An Imprintor-1 gene controls inactivation of the paternal copy of the mouse Tme locus

1992 • 102 citations

5 The origins of genomic imprinting in mammals

2002 • 93 citations

Tissue- and Developmental Stage-Specific Imprinting of the Mouse Proinsulin Gene, Ins2

1995 • 84 citations

Mit1/Lb9andCopg2, new members of mouse imprinted genes closely linked toPeg1/Mest

2000 • 56 citations

Lack of Reciprocal Genomic Imprinting of Sense and Antisense RNA of Mouse Insulin-like Growth Factor II Receptor in the Central Nervous System1

1999 • 47 citations

Characterization of the C3 YAC Contig from Proximal Mouse Chromosome 17 and Analysis of Allelic Expression of Genes Flanking the Imprinted Igf2r Gene

1997 • 46 citations

Cloning of the mouse organic cation transporter 2 gene, Slc22a2, from an enhancer-trap transgene integration locus

1999 • 45 citations

An imprinted transcript, antisense to Nesp, adds complexity to the cluster of imprinted genes at the mouse Gnas locus

2000 • 35 citations

Mothers Setting Boundaries

2000 • 22 citations