Mitochondrial calcium uptake
Data up to Jan 2025
Total Citations Per Year
Abstract
References (85)
Cardiac excitation–contraction coupling
2002 • 4,343 citations
A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
2011 • 1,752 citations
Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
2011 • 1,739 citations
Mechanisms by which mitochondria transport calcium
1990 • 1,630 citations
Excitation-Contraction Coupling and Cardiac Contractile Force
2001 • 1,509 citations
The mitochondrial calcium uniporter is a highly selective ion channel
2004 • 1,348 citations
The Ionic Channels in Excitable Membranes
1975 • 1,096 citations
Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin
1992 • 920 citations
MICU1 encodes a mitochondrial EF hand protein required for Ca2+ uptake
2010 • 830 citations
NCLX is an essential component of mitochondrial Na + /Ca 2+ exchange
2009 • 712 citations
Relaxation in rabbit and rat cardiac cells: species‐dependent differences in cellular mechanisms.
1994 • 661 citations
MICU1 Is an Essential Gatekeeper for MCU-Mediated Mitochondrial Ca2+ Uptake that Regulates Cell Survival
2012 • 580 citations
Calcium Sparks
2008 • 514 citations
Genome-Wide RNAi Screen Identifies Letm1 as a Mitochondrial Ca 2+ /H + Antiporter
2009 • 494 citations
Mitochondria buffer physiological calcium loads in cultured rat dorsal root ganglion neurons
1994 • 494 citations
MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism
2012 • 455 citations
MICU2, a Paralog of MICU1, Resides within the Mitochondrial Uniporter Complex to Regulate Calcium Handling
2013 • 436 citations
Regulation of the intracellular free calcium concentration in single rat dorsal root ganglion neurones in vitro.
1990 • 410 citations
Ultrastructural quantitation of mitochondria and myofilaments in cardiac muscle from 10 different animal species including man
1992 • 394 citations
An Integrated Model of Cardiac Mitochondrial Energy Metabolism and Calcium Dynamics
2003 • 380 citations
CaMKII determines mitochondrial stress responses in heart
2012 • 373 citations
Elevated Cytosolic Na + Decreases Mitochondrial Ca 2+ Uptake During Excitation-Contraction Coupling and Impairs Energetic Adaptation in Cardiac Myocytes
2006 • 344 citations
A survey of the interaction of calcium ions with mitochondria from different tissues and species
1971 • 339 citations
Termination of Cardiac Ca2+ Sparks: An Investigative Mathematical Model of Calcium-Induced Calcium Release
2002 • 297 citations
MCUR1は細胞代謝を制御するミトコンドリアCa 2MCUR1+ 取込の必須成分である
2012 • 270 citations
An FCCP-sensitive Ca2+ store in bullfrog sympathetic neurons and its participation in stimulus-evoked changes in [Ca2+]i
1994 • 262 citations
Mitochondrial control of calcium-channel gating: A mechanism for sustained signaling and transcriptional activation in T lymphocytes
2000 • 260 citations
Mechanisms for Intracellular Calcium Regulation in Heart
1973 • 253 citations
Activity of the mitochondrial calcium uniporter varies greatly between tissues
2012 • 215 citations
A Simple Numerical Model of Calcium Spark Formation and Detection in Cardiac Myocytes
1998 • 213 citations
Quantitative ultrastructural analysis in cardiac membrane physiology
1978 • 210 citations
A Computational Model Integrating Electrophysiology, Contraction, and Mitochondrial Bioenergetics in the Ventricular Myocyte
2006 • 207 citations
Mitochondrial Ca 2+ uptake contributes to buffering cytoplasmic Ca 2+ peaks in cardiomyocytes
2012 • 201 citations
Kinetic studies of Ca2+ binding and Ca2+ clearance in the cytosol of adrenal chromaffin cells
1997 • 199 citations
Minimal model of beta-cell mitochondrial Ca2+ handling
1997 • 195 citations
The Initial Velocities of Calcium Uptake by Rat Liver Mitochondria
1973 • 182 citations
Mitochondrial Ca2+ uptake prevents desynchronization of quantal release and minimizes depletion during repetitive stimulation of mouse motor nerve terminals
2003 • 171 citations
The Ca2+ transport mechanisms of mitochondria and Ca2+ uptake from physiological-type Ca2+ transients
1998 • 165 citations
Allosteric Regulation of Na/Ca Exchange Current by Cytosolic Ca in Intact Cardiac Myocytes
2001 • 161 citations
Evolutionary Diversity of the Mitochondrial Calcium Uniporter
2012 • 160 citations
The Mitochondrial Calcium Uniporter (MCU): Molecular Identity and Physiological Roles
2013 • 156 citations
Kinetics of calcium(2+) ion carrier in rat liver mitochondria
1979 • 143 citations
NCLX: The mitochondrial sodium calcium exchanger
2013 • 142 citations
Mitochondrial Ca2+ and the heart
2008 • 140 citations
Regulation of the Human Cardiac Mitochondrial Ca 2+ Uptake by 2 Different Voltage-Gated Ca 2+ Channels
2009 • 138 citations
Dynamics of Calcium Sparks and Calcium Leak in the Heart
2011 • 127 citations
The Role of Phosphate in the Regulation of the Independent Calcium‐Efflux Pathway of Liver Mitochondria
1982 • 124 citations
A Kinetic Study of Mitochondrial Calcium Transport
1975 • 120 citations
Measuring Local Gradients of Intramitochondrial [Ca 2+ ] in Cardiac Myocytes During Sarcoplasmic Reticulum Ca 2+ Release
2012 • 118 citations
Mitochondria Shape Hormonally Induced Cytoplasmic Calcium Oscillations and Modulate Exocytosis
2000 • 118 citations
Coupling between cytosolic and mitochondrial calcium oscillations: role in the regulation of hepatic metabolism
1998 • 111 citations
Stimulation-Evoked Increases in Cytosolic [Ca2+] in Mouse Motor Nerve Terminals Are Limited by Mitochondrial Uptake and Are Temperature-Dependent
2000 • 110 citations
The Regulation of Mitochondrial Calcium Transport in Heart
1985 • 102 citations
Mitochondrial Ca2+ uptake: Tortoise or hare?
2009 • 101 citations
Estimate of net calcium fluxes and sarcoplasmic reticulum calcium content during systole in rat ventricular myocytes.
1995 • 96 citations
Cytosolic and mitochondrial Ca2+ signals in patch clamped mammalian ventricular myocytes
1998 • 95 citations
Mitochondria in cardiomyocyte Ca2+ signaling
2009 • 93 citations
Dynamic Calcium Movement Inside Cardiac Sarcoplasmic Reticulum During Release
2011 • 92 citations
The role of calcium in the regulation of mitochondrial metabolism
1980 • 88 citations
A Thermodynamic Model of the Cardiac Sarcoplasmic/Endoplasmic Ca2+ (SERCA) Pump
2009 • 88 citations
Mitochondrial free calcium regulation during sarcoplasmic reticulum calcium release in rat cardiac myocytes
2009 • 78 citations
Mitochondrial Ca2+ mobilization is a key element in olfactory signaling
2012 • 70 citations
Effect of Ca2+ on cardiac mitochondrial energy production is modulated by Na+ and H+ dynamics
2007 • 65 citations
Morphometry of rat heart mitochondrial subcompartments and membranes: Application to myocardial cell atrophy after hypophysectomy
1976 • 63 citations
Simulation of Ca2+ Movements within the Sarcomere of Fast-Twitch Mouse Fibers Stimulated by Action Potentials
2007 • 61 citations
Mitochondrial Ca2+ influx and efflux rates in guinea pig cardiac mitochondria:Low and high affinity effects of cyclosporine A
2011 • 56 citations
Metabolic Regulation of Ca2+ Release in Permeabilized Mammalian Skeletal Muscle Fibres
2003 • 54 citations
A Biophysically Based Mathematical Model for the Kinetics of Mitochondrial Na+-Ca2+ Antiporter
2010 • 54 citations
Mitochondrial Calcium Signaling and Energy Metabolism
2005 • 52 citations
Differential impact of mitochondrial positioning on mitochondrial Ca2+ uptake and Ca2+ spark suppression in skeletal muscle
2011 • 51 citations
Calcium uptake in mitochondria from different skeletal muscle types
1985 • 51 citations
Calcium alternans in a couplon network model of ventricular myocytes: role of sarcoplasmic reticulum load
2012 • 49 citations
Changes in mitochondrial Ca2+ detected with Rhod-2 in single frog and mouse skeletal muscle fibres during and after repeated tetanic contractions.
2001 • 47 citations
A Biophysically Based Mathematical Model for the Kinetics of Mitochondrial Calcium Uniporter
2009 • 43 citations
Reversal of mitochondrial Na/Ca exchange during metabolic inhibition in rat cardiomyocytes
1999 • 42 citations
Net calcium exchange in adult rat ventricular myocytes: an assessment of mitochondrial calcium accumulating capacity
1984 • 38 citations
Contractile arrest increases sarcoplasmic reticulum calcium uptake and SERCA2 gene expression in cultured neonatal rat heart cells.
1994 • 36 citations
Purinergic signalling mobilizes mitochondrial Ca2+ in mouse Sertoli cells
2011 • 36 citations
Mitochondrial Ca2+ uptake prevents desynchronization of quantal release and minimizes depletion during repetitive stimulation of mouse motor nerve terminals
2003 • 32 citations
Mitochondrial function in intact skeletal muscle fibres of creatine kinase deficient mice
2003 • 30 citations
Toward an Integrative Computational Model of the Guinea Pig Cardiac Myocyte
2012 • 30 citations
“Allosteric Regulation” of Calcium-Uptake in Rat Liver Mitochondria
1986 • 26 citations
Modeling the mechanism of metabolic oscillations in ischemic cardiac myocytes
2006 • 22 citations
In vitro calcium transport properties of skeletal muscle mitochondria from vitamin D-deficient and 1,25-dihydroxy-vitamin D3-treated chicks
1990 • 10 citations
Uptake, retention, and efflux of Ca2+ by mitochondrial preparations from skeletal muscle
1984 • 9 citations