NCLX is an essential component of mitochondrial Na ⁺ /Ca ²⁺ exchange

Circularly permuted green fluorescent proteins engineered to sense Ca ²⁺

2001 • 941 citations

PINK1-Associated Parkinson's Disease Is Caused by Neuronal Vulnerability to Calcium-Induced Cell Death

2009 • 640 citations

Genome-Wide RNAi Screen Identifies Letm1 as a Mitochondrial Ca ²⁺ /H ⁺ Antiporter

2009 • 494 citations

Mitochondria: The Hub of Cellular Ca²⁺Signaling

2008 • 381 citations

Mitochondrial calcium transport: mechanisms and functions

2000 • 380 citations

Na+/Ca2+ exchangers: three mammalian gene families control Ca2+ transport

2007 • 366 citations

Active mitochondria surrounding the pancreatic acinar granule region prevent spreading of inositol trisphosphate-evoked local cytosolic Ca2+ signals

1999 • 362 citations

The release of calcium from heart mitochondria by sodium

1974 • 353 citations

The Calcium‐Induced and Sodium‐Induced Effluxes of Calcium from Heart Mitochondria

1977 • 265 citations

Stable Interactions between Mitochondria and Endoplasmic Reticulum Allow Rapid Accumulation of Calcium in a Subpopulation of Mitochondria

2003 • 225 citations

The Cation/Ca2+ Exchanger Superfamily: Phylogenetic Analysis and Structural Implications

2004 • 219 citations

Ca2+ Homeostasis during Mitochondrial Fragmentation and Perinuclear Clustering Induced by hFis1

2004 • 194 citations

Mitochondrial dynamics and Ca2+ signaling

2006 • 191 citations

In vivo monitoring of Ca2+ uptake into mitochondria of mouse skeletal muscle during contraction

2004 • 187 citations

Selectivity of Inhibition of Na+-Ca2+ Exchange of Heart Mitochondria by Benzothiazepine CGP-37157

1993 • 182 citations

Sustained Ca2+ Transfer across Mitochondria Is Essential for Mitochondrial Ca2+ Buffering, Store-operated Ca2+ Entry, and Ca2+ Store Refilling

2003 • 171 citations

A role for the mitochondrial Na(+)-Ca2+ exchanger in the regulation of oxidative phosphorylation in isolated heart mitochondria.

1993 • 159 citations

The Integration of Mitochondrial Calcium Transport and Storage

2004 • 157 citations

SLC24A5 Encodes a trans-Golgi Network Protein with Potassium-dependent Sodium-Calcium Exchange Activity That Regulates Human Epidermal Melanogenesis

2007 • 146 citations

Targeting of NH2-terminal–processed Microsomal Protein to Mitochondria: A Novel Pathway for the Biogenesis of Hepatic Mitochondrial P450MT2

1997 • 138 citations

Lithium-Calcium Exchange Is Mediated by a Distinct Potassium-independent Sodium-Calcium Exchanger

2004 • 136 citations

Molecular Cloning of a Sixth Member of the K+-dependent Na+/Ca2+ Exchanger Gene Family, NCKX6

2004 • 115 citations

Intermediate conductance Ca2+-activated potassium channel (KCa3.1) in the inner mitochondrial membrane of human colon cancer cells

2009 • 104 citations

Reconstitution, identification, purification, and immunological characterization of the 110-kDa Na+/Ca2+ antiporter from beef heart mitochondria.

1992 • 81 citations

Inhibition of Mitochondrial Na+-Ca2+ Exchanger Increases Mitochondrial Metabolism and Potentiates Glucose-Stimulated Insulin Secretion in Rat Pancreatic Islets

2003 • 74 citations

Mitochondrial Regulation of Sarcoplasmic Reticulum Ca ²⁺ Content in Vascular Smooth Muscle Cells

2008 • 65 citations

Rescue of Dysfunctional ΔF508-CFTR Chloride Channel Activity by IBMX

1999 • 59 citations

Molecular Control of Cardiac Sodium Homeostasis in Health and Disease

2006 • 49 citations

Kinetics and ion specificity of Na+/Ca2+ exchange mediated by the reconstituted beef heart mitochondrial Na+/Ca2+ antiporter

2004 • 48 citations

WITHDRAWN: Kinetics and ion specificity of Na+/Ca2+ exchange mediated by the reconstituted beef heart mitochondrial Na+/Ca2+ antiporter

2004 • 48 citations

Voltage-gated Ca2+ influx and insulin secretion in human and mouse β-cells are impaired by the mitochondrial Na+/Ca2+ exchange inhibitor CGP-37157

2007 • 40 citations

μ-Calpain mediated cleavage of the Na+/Ca2+ exchanger in isolated mitochondria under A23187 induced Ca2+ stimulation

2008 • 37 citations

Inhibition of plasmalemmal Na+/Ca2+ exchange by mitochondrial Na+/Ca2+ exchange inhibitor 7-chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one (CGP-37157) in cerebellar granule cells

2003 • 36 citations

Role of mitochondria in spontaneous rhythmic activity and intracellular calcium waves in the guinea pig gallbladder smooth muscle

2007 • 33 citations

Single α-Domain Constructs of the Na⁺/Ca²⁺Exchanger, NCLX, Oligomerize To Form a Functional Exchanger

2006 • 29 citations

Presence of Sodium?Calcium Exchanger/GM1 Complex in the Nuclear Envelope of Non-neural Cells: Nature of Exchanger-GM1 Interaction

2004 • 26 citations

Inhibition of Canine (NCX1.1) andDrosophila(CALX1.1) Na⁺-Ca²⁺Exchangers by 7-Chloro-3,5-dihydro-5-phenyl-1H-4,1-benzothiazepine-2-one (CGP-37157)

2003 • 23 citations

Vesicular transport of newly synthesized cytochromes P4501A to the outside of rat hepatocyte plasma membranes.

2000 • 15 citations