Mast cells are required for optimal autoreactive T cell responses in a murine model of multiple sclerosis

Mast cells in the development of adaptive immune responses

2005 • 1,252 citations

Mast cell lines produce lymphokines in response to cross-linkage of FcεRI or to calcium ionophores

1989 • 1,199 citations

Multiple Sclerosis: A Coordinated Immunological Attack against Myelin in the Central Nervous System

1996 • 903 citations

Inflammatory mediators and modulation of blood-brain barrier permeability.

2000 • 769 citations

A Pathogenic Role for Myelin-Specific Cd8+ T Cells in a Model for Multiple Sclerosis

2001 • 650 citations

Multiple sclerosis: a two-stage disease

2001 • 602 citations

Histamine regulates T-cell and antibody responses by differential expression of H1 and H2 receptors

2001 • 578 citations

Granulocyte Macrophage Colony-Stimulating Factor

2001 • 457 citations

Myelin Antigen-Specific CD8+ T Cells Are Encephalitogenic and Produce Severe Disease in C57BL/6 Mice

2001 • 437 citations

Mast Cells Are Essential for Early Onset and Severe Disease in a Murine Model of Multiple Sclerosis

2000 • 427 citations

Protective Roles of Mast Cells Against Enterobacterial Infection Are Mediated by Toll-Like Receptor 4

2001 • 373 citations

T Cell Response in Experimental Autoimmune Encephalomyelitis (EAE): Role of Self and Cross-Reactive Antigens in Shaping, Tuning, and Regulating the Autopathogenic T Cell Repertoire

2002 • 371 citations

B cell stimulatory factor-1/interleukin-4 mRNA is expressed by normal and transformed mast cells

1987 • 355 citations

Mast cell–derived tumor necrosis factor induces hypertrophy of draining lymph nodes during infection

2003 • 312 citations

Histamine regulates cytokine production in maturing dendritic cells, resulting in altered T cell polarization

2001 • 312 citations

Histamine regulates cytokine production in maturing dendritic cells, resulting in altered T cell polarization

2001 • 292 citations

Antibodies to CD44 and integrin α₄, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment

1999 • 287 citations

Mast cell–dependent migration of effector CD8+ T cells through production of leukotriene B4

2003 • 282 citations

Mast cells enhance T cell activation: Importance of mast cell-derived TNF

2005 • 249 citations

Genetically mast-cell-deficient W/Wv and Sl/Sld mice. Their value for the analysis of the roles of mast cells in biologic responses in vivo.

1987 • 206 citations

Pro-Thymocyte Expansion by c-kit and the Common Cytokine Receptor γ Chain Is Essential for Repertoire Formation

1997 • 195 citations

De Novo Central Nervous System Processing of Myelin Antigen Is Required for the Initiation of Experimental Autoimmune Encephalomyelitis

2002 • 191 citations

Viable c-KitW/W Mutants Reveal Pivotal Role for c-Kit in the Maintenance of Lymphopoiesis

2002 • 182 citations

Antigen-dependent stimulation by bone marrow-derived mast cells of MHC class II-restricted T cell hybridoma.

1993 • 176 citations

Migration and Function of Antigen-Primed Nonpolarized T Lymphocytes in Vivo

2001 • 176 citations

Mast cell activation and migration to lymph nodes during induction of an immune response in mice.

1998 • 173 citations

T Cell Proliferation by Direct Cross-Talk between OX40 Ligand on Human Mast Cells and OX40 on Human T Cells: Comparison of Gene Expression Profiles between Human Tonsillar and Lung-Cultured Mast Cells

2004 • 159 citations

Identification of Bphs , an Autoimmune Disease Locus, as Histamine Receptor H ₁

2002 • 149 citations

Interleukin (IL)-4 inhibits IL-10 to promote IL-12 production by dendritic cells

2005 • 148 citations

Specificity, magnitude, and kinetics of MOG‐specific CD8⁺ T cell responses during experimental autoimmune encephalomyelitis

2004 • 137 citations

IgE-Mediated Mast Cell Activation Induces Langerhans Cell Migration In Vivo

2004 • 131 citations

Mast Cells Exert Effects Outside the Central Nervous System to Influence Experimental Allergic Encephalomyelitis Disease Course

2003 • 126 citations

Myelin-Specific Cd8 T Cells in the Pathogenesis of Experimental Allergic Encephalitis and Multiple Sclerosis

2001 • 114 citations

Regulation of T lymphocyte trafficking into lymph nodes during an immune response by the chemokines macrophage inflammatory protein (MIP)-1 alpha and MIP-1 beta.

1998 • 112 citations

The mast cells of the multiple sclerosis brain

1996 • 107 citations

Rat Peritoneal Mast Cells Present Antigen to a PPD-Specific T Cell Line

1994 • 103 citations

TNF accelerates the onset but does not alter the incidence and severity of myelin basic protein-induced experimental autoimmune encephalomyelitis

1999 • 93 citations

Regulation of T Lymphocyte Trafficking into Lymph Nodes During an Immune Response by the Chemokines Macrophage Inflammatory Protein (MIP)-1α and MIP-1β

1998 • 87 citations

Unravelling the mast cell dilemma: culprit or victim of its generosity?

1997 • 73 citations

Presentation of Soluble Antigens by Mast Cells: Upregulation by Interleukin-4 and Granulocyte/Macrophage Colony-Stimulating Factor and Downregulation by Interferon-γ

1995 • 72 citations

Attenuation of Th1 Effector Cell Responses and Susceptibility to Experimental Allergic Encephalomyelitis in Histamine H2 Receptor Knockout Mice Is Due to Dysregulation of Cytokine Production by Antigen-Presenting Cells

2004 • 69 citations

Role of the IL-12/IL-23 System in the Regulation of T-Cell Responses in Central Nervous System Inflammatory Demyelination;

2004 • 67 citations

Ueber das Vorkommen der sogenannten „Mastzellen” bei pathologischen Veränderungen des Gehirns

1890 • 47 citations

Murine cell lines stably expressing the influenza virus hemagglutinin gene introduced by a recombinant retrovirus vector are constitutive targets for MHC class I- and class II-restricted T lymphocytes.

1989 • 26 citations