Genetically mast-cell-deficient W/Wv and Sl/Sld mice. Their value for the analysis of the roles of mast cells in biologic responses in vivo.

Hereditary Anemias of the Mouse: A Review for Geneticists

1979 • 1,141 citations

Decrease of mast cells in W/Wv mice and their increase by bone marrow transplantation

1978 • 846 citations

Fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient W/Wv mice. Evidence that cultured mast cells can give rise to both connective tissue type and mucosal mast cells.

1985 • 503 citations

The mast cell.

1981 • 399 citations

Decreased production of mast cells in S1/S1d anemic mice

1979 • 372 citations

Activation of Mast Cells for Mediator Release through IgE Receptors

2015 • 369 citations

The Cellular Basis of the Genetically Determined Hemopoietic Defect in Anemic Mice of Genotype Sl/Sld

1965 • 345 citations

Spleen-Colony Formation in Anemic Mice of Genotype WW ^V

1964 • 331 citations

Structure and Function of the Chemical Mediators of Mast Cells

2015 • 295 citations

Basophils and Mast Cells: Morphologic Insights into Their Biology, Secretory Patterns, and Function1

2015 • 242 citations

Tissue distribution of histamine in a mutant mouse deficient in mast cells

1982 • 155 citations

Defective elicitation of delayed-type hypersensitivity in W/Wv and SI/SId mast cell-deficient mice.

1983 • 124 citations

Unequivocal Delayed Hypersensitivity in Mast Cell-Deficient and Beige Mice

1984 • 121 citations

Ultrastructural identification of the mouse basophil

1982 • 106 citations

Decreased neutrophils and megakaryocytes in anemic mice of genotypeW/Wv

1969 • 86 citations

Mast cells in spotted mutant mice ( W Ph mi )

1982 • 86 citations

Effect of α‐Fluoromethylhistidine on the Histamine Content of the Brain of W/W^v Mice Devoid of Mast Cells: Turnover of Brain Histamine

1983 • 73 citations

Anaphylaxis in Mast Cell-Deficient Mice

1984 • 70 citations

Immune Response Potential of Mast Cell-Deficient W/W<sup>v</sup> Mice

1986 • 68 citations

Hyperplastic and early neoplastic changes in the ovaries of mice after genic deletion of germ cells.

1972 • 61 citations

Abnormal mast cell granules in the beige (Chédiak-Higashi syndrome) mouse.

1975 • 60 citations

Growth and Differentiation of Transplanted W/Wv Marrow

1967 • 57 citations

Delayed hypersensitivity in mast-cell-deficient mice.

1983 • 57 citations

Proliferation of peritoneal mast cells in the skin of W/Wv mice that genetically lack mast cells.

1984 • 54 citations

A kinetic study of the genetic control of hemopoietic progenitor cells assayed in culture and In vivo

1970 • 53 citations

Abnormalities of Megakaryocytes in W/Wv Mice

1973 • 52 citations

A New Look at Basophils in Mice

1981 • 51 citations

Concentration of mast‐cell progenitors in bone marrow, spleen, and blood of mice determined by limiting dilution analysis

1982 • 51 citations

Abnormalities of Megakaryocytes in Sl/Sld Mice

1973 • 50 citations

Spontaneous stomach ulcer in genetically mast-cell depleted W/Wv mice

1980 • 50 citations

Coincidental development of forestomach papilloma and prepyloric ulcer in nontreated mutant mice of W/Wv and SI/SId genotypes.

1980 • 48 citations

The Significance of Mast Cells as a Source of Histamine in the Mouse Brain

1984 • 48 citations

B lymphocyte precursors in embryonic and adult W anemic mice.

1984 • 46 citations

Undiminished immunologic tolerance to contact sensitivity in mast cell-deficient W/Wv and Sl/Sld mice.

1985 • 46 citations

What do mast cells have to do with delayed hypersensitivity?

1984 • 45 citations

Receptors for IgE on Mast Cells and Basophils

2015 • 45 citations

Increase in histidine decarboxylase activity in skin of genetically mast-cell-deficient W/Wv mice after application of phorbol 12-myristate 13-acetate: evidence for the presence of histamine-producing cells without basophilic granules.

1982 • 44 citations

Anticoagulantly active heparin-like molecules from mast cell-deficient mice

1986 • 44 citations

Reevaluation of reserpine-induced suppression of contact sensitivity. Evidence that reserpine interferes with T lymphocyte function independently of an effect on mast cells.

1985 • 42 citations

The Immune Response in Mice of Genotypes W/Wv and Sl/Sld1

1969 • 40 citations

Absence of heparin or heparine-like compounds in mast-cell-free tissues and animals

1982 • 36 citations

Higher susceptibility of mast-cell-deficient W/WV mutant mice to brain thromboembolism and mortality caused by intravenous injection of India ink.

1986 • 35 citations

Differentiation Processes of Connective Tissue Mast Cells in Living Mice

1985 • 34 citations

The contribution of mast cells to the histamine content of the central nervous system: A regional analysis

1982 • 29 citations

Analysis of the hematopoietic effects of new dominant spotting (W) mutations of the mouse. II. Effects on mast cell development.

1983 • 28 citations

Dural Mast Cells: Source of Contaminating Histamine in Analyses of Mouse Brain Histamine Levels

1984 • 23 citations

Effect of the Slt mutant allele on the production of tissue mast cells in mice

1983 • 20 citations

Distribution of 5-hydroxytryptamine (5HT) in tissue of a mutant mouse deficient in mast cell (W/W v ). Demonstration of the contribution of mast cells to the 5HT content in various organs

1985 • 20 citations

Megakaryocytic responses to thrombocytopenia and thrombocytosis in Sl/Sld mice.

1978 • 18 citations

125I-fibrin deposition in contact sensitivity reactions in the mouse. Sensitivity of the assay for quantitating reactions after active or passive sensitization.

1986 • 17 citations

Effects of Mutant Steel Alleles on Leukemogenesis and Life-Span in the Mouse2

1977 • 15 citations

Normal levels of histamine and Tele-Methylhistamine in mast cell-deficient mouse brain

1984 • 15 citations

The role of specific forms of heparan sulfate in regulating blood vessel wall function.

1986 • 14 citations

Regulation of megakaryocytes in W/W^v mice

1978 • 12 citations

Fatal antral ulcer in conventionally fed W/Wv mutant mice given indomethacin by injection.

1985 • 7 citations

Measurement of Thrombocytopoiesis in W/Wv Mice with Evidence for an Abnormality of Sulfate Metabolism

1981 • 5 citations