Chemokine Regulation of Normal and Pathologic Immune Responses

Atherosclerosis — An Inflammatory Disease

1999 • 21,494 citations

Involvement of chemokine receptors in breast cancer metastasis

2001 • 5,203 citations

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1996 • 4,184 citations

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

1996 • 3,189 citations

Chemokines and leukocyte traffic

1998 • 2,755 citations

CC CKR5: A RANTES, MIP-1α, MIP-1β Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1

1996 • 2,735 citations

The Biology of Chemokines and their Receptors

2000 • 2,416 citations

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

1996 • 2,374 citations

CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs

1999 • 2,326 citations

CHEMOKINE RECEPTORS AS HIV-1 CORECEPTORS: Roles in Viral Entry, Tropism, and Disease

1999 • 2,174 citations

Chemokines

1997 • 1,926 citations

Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

1998 • 1,687 citations

T-Cell Function and Migration — Two Sides of the Same Coin

2000 • 1,437 citations

Chemokines and disease

2001 • 1,371 citations

A chemokine-driven positive feedback loop organizes lymphoid follicles

2000 • 1,220 citations

The Role of Chemokine Receptors in Primary, Effector, and Memory Immune Responses

2000 • 1,077 citations

Chemokines and Cell Migration in Secondary Lymphoid Organs

1999 • 1,046 citations

Mice Lacking Expression of Secondary Lymphoid Organ Chemokine Have Defects in Lymphocyte Homing and Dendritic Cell Localization

1999 • 1,030 citations

Chemokines and the Arrest of Lymphocytes Rolling Under Flow Conditions

1998 • 1,013 citations

A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes

1998 • 1,001 citations

Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients

1999 • 999 citations

Roles of PLC-β2 and -β3 and PI3Kγ in Chemoattractant-Mediated Signal Transduction

2000 • 825 citations

Chemokines in tissue-specific and microenvironment-specific lymphocyte homing

2000 • 643 citations

Chemokines, leukocyte trafficking, and inflammation

1994 • 636 citations

Dancing to the tune of chemokines

2001 • 624 citations

Cutting Edge: Secondary Lymphoid-Tissue Chemokine (SLC) and CC Chemokine Receptor 7 (CCR7) Participate in the Emigration Pathway of Mature Dendritic Cells from the Skin to Regional Lymph Nodes

1999 • 621 citations

Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in theplt/pltmouse

2000 • 580 citations

Localization of Distinct Peyer's Patch Dendritic Cell Subsets and Their Recruitment by Chemokines Macrophage Inflammatory Protein (Mip)-3α, Mip-3β, and Secondary Lymphoid Organ Chemokine

2000 • 578 citations

The Coordinated Action of CC Chemokines in the Lung Orchestrates Allergic Inflammation and Airway Hyperresponsiveness

1998 • 546 citations

CC chemokines in allergic inflammation

1994 • 540 citations

Cc Chemokine Receptor 2 Is Critical for Induction of Experimental Autoimmune Encephalomyelitis

2000 • 510 citations

Alpha and beta chemokines induce NK cell migration and enhance NK-mediated cytolysis.

1995 • 459 citations

The Cc Chemokine Thymus-Derived Chemotactic Agent 4 (Tca-4, Secondary Lymphoid Tissue Chemokine, 6ckine, Exodus-2) Triggers Lymphocyte Function–Associated Antigen 1–Mediated Arrest of Rolling T Lymphocytes in Peripheral Lymph Node High Endothelial Venules

2000 • 420 citations

Molecular Cloning of a Novel Human CC Chemokine EBI1-ligand Chemokine That Is a Specific Functional Ligand for EBI1, CCR7

1997 • 405 citations

Molecular Cloning of a Novel Human CC Chemokine Liver and Activation-regulated Chemokine (LARC) Expressed in Liver

1997 • 354 citations

Chemokines: signal lamps for trafficking of T and B cells for development and effector function

1999 • 348 citations

Viral exploitation and subversion of the immune system through chemokine mimicry

2001 • 334 citations

6-C-kine (SLC), a Lymphocyte Adhesion-triggering Chemokine Expressed by High Endothelium, Is an Agonist for the MIP-3β Receptor CCR7

1998 • 331 citations

Identification through bioinformatics of two new macrophage proinflammatory human chemokines: MIP-3alpha and MIP-3beta.

1997 • 318 citations

Chemokines and tissue injury.

1995 • 303 citations

Chemokines and Chemokine Receptors: Biology and Clinical Relevance in Inflammation and AIDS

1999 • 293 citations

Interleukin-10 expression and chemokine regulation during the evolution of murine type II collagen-induced arthritis.

1995 • 269 citations

Stromal cell-derived factor-1α stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells: roles of phosphoinositide-3 kinase and protein kinase C

2000 • 266 citations

Molecular Cloning of a Novel Human CC Chemokine Secondary Lymphoid-Tissue Chemokine That Is a Potent Chemoattractant for Lymphocytes and Mapped to Chromosome 9p13

1997 • 260 citations

Chemotaxis of primitive hematopoietic cells in response to stromal cell–derived factor-1

2000 • 255 citations

The CC chemokine receptor-7 ligands 6Ckine and macrophage inflammatory protein-3 beta are potent chemoattractants for in vitro- and in vivo-derived dendritic cells.

1999 • 251 citations

"The good, the bad, and the ugly." The role of chemokines in models of human disease.

1996 • 250 citations

The Reduced Expression of 6ckine in the plt Mouse Results from the Deletion of One of Two 6ckine Genes

1999 • 217 citations

Combined chemokine and cytokine gene transfer enhances antitumor immunity

1996 • 215 citations

Gene Duplications at the Chemokine Locus on Mouse Chromosome 4: Multiple Strain-Specific Haplotypes and the Deletion of Secondary Lymphoid-Organ Chemokine and EBI-1 Ligand Chemokine Genes in thepltMutation

2001 • 210 citations

BIOMEDICINE:The Enigmas of Kaposi's Sarcoma

1998 • 204 citations

Secondary Lymphoid Tissue Chemokine Mediates T Cell-Dependent Antitumor Responses In Vivo

2000 • 202 citations

The CC Chemokine Receptor-7 Ligands 6Ckine and Macrophage Inflammatory Protein-3β Are Potent Chemoattractants for In Vitro- and In Vivo-Derived Dendritic Cells

1999 • 195 citations

Lymphoid Tissue Homing Chemokines Are Expressed in Chronic Inflammation

2000 • 193 citations

Gβγ Stimulates Phosphoinositide 3-Kinase-γ by Direct Interaction with Two Domains of the Catalytic p110 Subunit

1998 • 191 citations

Lymphotactin is produced by NK cells and attracts both NK cells and T cells in vivo.

1997 • 191 citations

A Novel Mutant Gene Involved in T-Lymphocyte–Specific Homing Into Peripheral Lymphoid Organs on Mouse Chromosome 4

1998 • 187 citations

Mice Lacking Expression of the Chemokines Ccl21-Ser and Ccl19 (plt Mice) Demonstrate Delayed but Enhanced T Cell Immune Responses

2001 • 187 citations

Demonstration of stem cell inhibition and myeloprotective effects of SCI/rhMIP1 alpha in vivo

1992 • 178 citations

Chemokines and their receptors in allograft rejection

2000 • 177 citations

Cloning and Characterization of Exodus, a Novel β-Chemokine

1997 • 176 citations

Identification and characterization of a novel beta chemokine containing six conserved cysteines.

1997 • 166 citations

Expression of the chemokine superfamily in rheumatoid arthritis

1994 • 164 citations

Antitumor Effects of the Mouse Chemokine 6Ckine/SLC Through Angiostatic and Immunological Mechanisms

2000 • 156 citations

Isolation and characterization of Exodus-2, a novel C-C chemokine with a unique 37-amino acid carboxyl-terminal extension.

1997 • 142 citations

Chemokines, chemokine receptors and hematopoiesis

2000 • 142 citations

Genetic defect in T lymphocyte‐specific homing into peripheral lymph nodes

1997 • 138 citations

Unresponsiveness of primitive chronic myeloid leukemia cells to macrophage inflammatory protein 1 alpha, an inhibitor of primitive normal hematopoietic cells.

1993 • 125 citations

The CC Chemokine CKβ-11/MIP-3β/ELC/Exodus 3 Mediates Tumor Rejection of Murine Breast Cancer Cells Through NK Cells

2000 • 124 citations

Chemokine stromal cell-derived factor-1α modulates VLA-4 integrin-dependent adhesion to fibronectin and VCAM-1 on bone marrow hematopoietic progenitor cells

2001 • 121 citations

Identification of a new mouse beta-chemokine, thymus-derived chemotactic agent 4, with activity on T lymphocytes and mesangial cells.

1997 • 118 citations

Leukocyte migration: Scent of the T zone

2000 • 116 citations

Chemokine signaling in inflammation

2000 • 115 citations

Macrophage-inflammatory protein protects multipotent hematopoietic cells from the cytotoxic effects of hydroxyurea in vivo

1992 • 114 citations

Macrophage-inflammatory protein protects multipotent hematopoietic cells from the cytotoxic effects of hydroxyurea in vivo

1992 • 92 citations

Inhibition of in vivo tumor growth by the beta chemokine, TCA3.

1994 • 83 citations

A High Endothelial Cell-Derived Chemokine Induces Rapid, Efficient, and Subset-Selective Arrest of Rolling T Lymphocytes on a Reconstituted Endothelial Substrate

1998 • 83 citations

Functional characterization of the C—C chemokine-like molecules encoded by molluscum contagiosum virus types 1 and 2

1997 • 79 citations

SLC/Exodus2/6Ckine/TCA4 induces chemotaxis of hematopoietic progenitor cells: differential activity of ligands of CCR7, CXCR3, or CXCR4 in chemotaxis vs. suppression of progenitor proliferation

1999 • 74 citations

Role of early reperfusion in the induction of adhesion molecules and cytokines in previously ischemic myocardium

1995 • 65 citations

Monocyte chemoattractant protein-1 (MCP-1) gene transduction: an effective tumor vaccine strategy for non-intracranial tumors

1995 • 58 citations

Regulation of Human Natural Killer Cell Migration and Proliferation by the Exodus Subfamily of CC Chemokines

2000 • 49 citations

Myeloid Progenitor Cell Proliferation and Mobilization Effects of BB10010, a Genetically Engineered Variant of Human Macrophage Inflammatory Protein-1α, in a Phase I Clinical Trial in Patients with Relapsed/Refractory Breast Cancer

1998 • 46 citations

Cardiac myocytes release leukocyte-stimulating factors

1995 • 42 citations

Differences between normal and cml stem cells: Potential targets for clinical exploitation

2009 • 40 citations

Overview of Chemokines

1993 • 38 citations

Role of Chemokines in Inflammation and Immunoregulation

2000 • 34 citations

Structural biology of chemokine receptors

1999 • 27 citations

The Exodus subfamily of CC chemokines inhibits the proliferation of chronic myelogenous leukemia progenitors

2000 • 23 citations

Chemokines and anti-cancer immunotherapy: anti-tumor effect of EBI1-ligand chemokine (ELC) and secondary lymphoid tissue chemokine (SLC).

2000 • 16 citations

Chemokines and Chemokine Receptors in T-Cell Development

1999 • 9 citations