The Coordinated Action of CC Chemokines in the Lung Orchestrates Allergic Inflammation and Airway Hyperresponsiveness

Secretory products of macrophages.

1987 • 2,670 citations

Interleukin-8 and related chemotactic cytokines--CXC and CC chemokines.

1994 • 2,251 citations

lnterleukin-8 and Related Chemotactic Cytokines—CXC and CC Chemokines

1993 • 1,650 citations

Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model.

1996 • 1,382 citations

Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation.

1994 • 822 citations

Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines.

1992 • 737 citations

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.

1996 • 734 citations

Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils.

1996 • 719 citations

The eosinophil and bronchial asthma: Current understanding

1990 • 688 citations

Eosinophils, T-lymphocytes, mast cells, neutrophils, and macrophages in bronchial biopsy specimens from atopic subjects with asthma: Comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship to bronchial hyperresponsiveness

1991 • 681 citations

RANTES and macrophage inflammatory protein 1 alpha induce the migration and activation of normal human eosinophil granulocytes.

1992 • 620 citations

Cytokine-activated human endothelial cells synthesize and secrete a monocyte chemoattractant, MCP-1/JE.

1990 • 500 citations

Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia.

1994 • 498 citations

RANTES and Monocyte Chemoattractant Protein–1 (MCP-1) Play an Important Role in the Inflammatory Phase of Crescentic Nephritis, but Only MCP-1 Is Involved in Crescent Formation and Interstitial Fibrosis

1997 • 498 citations

Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties.

1988 • 444 citations

Eosinophil recruitment to the lung in a murine model of allergic inflammation. The role of T cells, chemokines, and adhesion receptors.

1996 • 436 citations

Extension of Recombinant Human RANTES by the Retention of the Initiating Methionine Produces a Potent Antagonist

1996 • 424 citations

Interleukin-4 is required for the induction of lung Th2 mucosal immunity.

1995 • 364 citations

Murine eotaxin: an eosinophil chemoattractant inducible in endothelial cells and in interleukin 4-induced tumor suppression.

1995 • 351 citations

Actions of the chemotactic cytokines MCP‐1, MCP‐2, MCP‐3, RANTES, MIP‐1α and MIP‐1β on human monocytes

1995 • 349 citations

The eosinophil as a mediator of damage to respiratory epithelium: A model for bronchial hyperreactivity

1988 • 317 citations

Human alveolar macrophages produce leukotriene B4.

1982 • 278 citations

Mouse Eotaxin Expression Parallels Eosinophil Accumulation during Lung Allergic Inflammation but It Is Not Restricted to a Th2-Type Response

1996 • 260 citations

Role of monocyte chemoattractant protein-1 (MCP-1) in Th1 (mycobacterial) and Th2 (schistosomal) antigen-induced granuloma formation: relationship to local inflammation, Th cell expression, and IL-12 production.

1996 • 251 citations

Monocyte chemoattractant protein-1 is sufficient for the chemotaxis of monocytes and lymphocytes in transgenic mice but requires an additional stimulus for inflammatory activation.

1997 • 209 citations

Eosinophil recruitment into the respiratory epithelium following antigenic challenge in hyper-IgE mice is accompanied by interleukin 5-dependent bronchial hyperresponsiveness.

1995 • 195 citations

Differential recruitment of leukocyte populations and alteration of airway hyperreactivity by C-C family chemokines in allergic airway inflammation.

1997 • 177 citations

Eosinophil transendothelial migration induced by cytokines. III. Effect of the chemokine RANTES.

1994 • 175 citations

Differential interleukin 1 elaboration by unfractionated and density fractionated human alveolar macrophages and blood monocytes: relationship to cell maturity.

1985 • 133 citations

T cell-dependent regulation of eotaxin in antigen-induced pulmonary eosinophila.

1996 • 126 citations

Distinct expression and function of the novel mouse chemokine monocyte chemotactic protein-5 in lung allergic inflammation.

1996 • 100 citations

Selective eosinophil transendothelial migration triggered by eotaxin via modulation of Mac-1/ICAM-1 and VLA-4/VCAM-1 interactions

1999 • 93 citations

Macrophage inflammatory protein‐1α influences eosinophil recruitment in antigen‐specific airway inflammation

1995 • 93 citations

Activation and regulation of chemokines in allergic airway inflammation

1996 • 92 citations

Identification and characterization of a monocyte-derived neutrophil-activating factor in corticosteroid-resistant bronchial asthma.

1989 • 85 citations

The Chemotactic Cytokine Eotaxin Acts as a Granulocyte-Macrophage Colony-Stimulating Factor During Lung Inflammation

1998 • 64 citations

Serologic analysis of the mouse beta chemokine JE/monocyte chemoattractant protein-1.

1994 • 41 citations

[The eosinophil and bronchial asthma].

1993 • 30 citations

A sensitive and efficient induction system for murine IgE single cell analysis at the clonal level

1991 • 16 citations