Elevation of Manganese Superoxide Dismutase Gene Expression by Thioredoxin

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

SUPEROXIDE RADICAL AND SUPEROXIDE DISMUTASES

1995 • 3,305 citations

THIOREDOXIN

1985 • 1,885 citations

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

1995 • 1,761 citations

Thioredoxin-dependent peroxide reductase from yeast.

1994 • 940 citations

Induction of Manganous Superoxide Dismutase by Tumor Necrosis Factor: Possible Protective Mechanism

1988 • 933 citations

Thiordoxin regulates the DNA binding activity of NF-χB by reduction of a disulphid bond involving cysteine 62

1992 • 825 citations

Hyperoxia increases oxygen radical production in rat lungs and lung mitochondria.

1981 • 757 citations

An assay for superoxide dismutase activity in mammalian tissue homogenates

1989 • 702 citations

Structural and biochemical changes in rat lungs occurring during exposures to lethal and adaptive doses of oxygen.

1980 • 678 citations

Rat liver thioredoxin and thioredoxin reductase: purification and characterization

1982 • 610 citations

Superoxide sensitivity of the Escherichia coli aconitase.

1991 • 499 citations

Oxidoreductive regulation of nuclear factor kappa B. Involvement of a cellular reducing catalyst thioredoxin

1993 • 490 citations

Superoxide Radical and Iron Modulate Aconitase Activity in Mammalian Cells

1995 • 467 citations

Secretion of thioredoxin by normal and neoplastic cells through a leaderless secretory pathway.

1992 • 463 citations

Aconitase is a sensitive and critical target of oxygen poisoning in cultured mammalian cells and in rat lungs.

1994 • 415 citations

Differential regulation of antioxidant enzymes in response to oxidants.

1991 • 411 citations

Regulation of manganese superoxide dismutase by lipopolysaccharide, interleukin-1, and tumor necrosis factor. Role in the acute inflammatory response.

1990 • 382 citations

Differential reactivity of the functional sulfhydryl groups of cysteine-32 and cysteine-35 present in the reduced form of thioredoxin from Escherichia coli.

1980 • 364 citations

The thioredoxin and glutaredoxin systems are efficient electron donors to human plasma glutathione peroxidase.

1994 • 361 citations

Inactivation-reactivation of aconitase in Escherichia coli. A sensitive measure of superoxide radical.

1992 • 336 citations

Reduction of disulfides by thioredoxin. Exceptional reactivity of insulin and suggested functions of thioredoxin in mechanism of hormone action.

1979 • 324 citations

Human Mn-superoxide dismutase in pulmonary epithelial cells of transgenic mice confers protection from oxygen injury.

1992 • 321 citations

Human Thioredoxin Reductase Directly Reduces Lipid Hydroperoxides by NADPH and Selenocystine Strongly Stimulates the Reaction via Catalytically Generated Selenols

1995 • 315 citations

Studies on Cytochrome c Peroxidase

1965 • 276 citations

Adult T cell leukemia-derived factor/human thioredoxin protects endothelial F-2 cell injury caused by activated neutrophils or hydrogen peroxide

1994 • 252 citations

Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NFκB

1995 • 224 citations

Removal of Hydrogen Peroxide by Thiol-specific Antioxidant Enzyme (TSA) Is Involved with Its Antioxidant Properties

1996 • 222 citations

The effect of H2O2 upon thioredoxin-enriched lens epithelial cells.

1988 • 214 citations

Thioredoxin regenerates proteins inactivated by oxidative stress in endothelial cells

1992 • 210 citations

Redox control of resistance to cis-diamminedichloroplatinum (II) (CDDP): protective effect of human thioredoxin against CDDP-induced cytotoxicity.

1996 • 203 citations

A Genetic Tool Used to Identify Thioredoxin as a Mediator of a Growth Inhibitory Signal

1991 • 189 citations

The Association of Circulating Endotoxin with the Development of the Adult Respiratory Distress Syndrome

1989 • 182 citations

Activation of NF-kappa B and elevation of MnSOD gene expression by thiol reducing agents in lung adenocarcinoma (A549) cells

1995 • 174 citations

Transfection with human thioredoxin increases cell proliferation and a dominant-negative mutant thioredoxin reverses the transformed phenotype of human breast cancer cells.

1996 • 161 citations

ATP-dependent Regulation of Sodium-Calcium Exchange in Chinese Hamster Ovary Cells Transfected with the Bovine Cardiac Sodium-Calcium Exchanger

1995 • 160 citations

Tolerance of rats to hyperoxia. Lung antioxidant enzyme gene expression.

1993 • 159 citations

A Novel Promoter Sequence Is Involved in the Oxidative Stress-Induced Expression of the Adult T-Cell Leukemia-Derived Factor (ADF)/Human Thioredoxin (Trx) Gene

1996 • 145 citations

Manganese superoxide dismutase is induced by IFN-gamma in multiple cell types. Synergistic induction by IFN-gamma and tumor necrosis factor or IL-1.

1991 • 140 citations

Thiol modulation of TNF? and IL-1 induced MnSOD gene expression and activation of NF-?B

1995 • 128 citations

Sensitization of human renal cell carcinoma cells to cis-diamminedichloroplatinum(II) by anti-interleukin 6 monoclonal antibody or anti-interleukin 6 receptor monoclonal antibody.

1995 • 127 citations

Expression of antioxidant enzymes in rat kidney during ischemia-reperfusion injury

1993 • 99 citations

Superoxide Scavenging by Mn(II/III) Tetrakis (1-Methyl-4-pyridyl) Porphyrin in Mammalian Cells

1996 • 97 citations

Purification of human thioredoxin reductase: Properties and characterization by absorption and circular dichroism spectroscopy

1993 • 96 citations

Antioxidant Enzyme Activity in Alveolar Type II Cells after Exposure of Rats to Hyperoxia

1986 • 96 citations

Inhibition of Metal-Catalyzed Oxidation Systems by a Yeast Protector Protein in the Presence of Thioredoxin

1994 • 88 citations

Nitric oxide-induced inhibition of lung endothelial cell nitric oxide synthase via interaction with allosteric thiols: role of thioredoxin in regulation of catalytic activity.

1996 • 84 citations

Effects of TNF-alpha and phorbol ester on human surfactant protein and MnSOD gene transcription in vitro

1992 • 83 citations

The thioredoxin/thioredoxin reductase redox system and control of cell growth.

1994 • 76 citations

Manganese-superoxide dismutase in endothelial cells: localization and mechanism of induction

1993 • 69 citations

Oxidative stress induces adult T cell leukemia derived factor/thioredoxin in the rat retina.

1994 • 67 citations

Antioxidant enzymes of rat granular pneumocytes. Constitutive levels and effect of hyperoxia.

1981 • 65 citations

Genomic cloning of human thioredoxin-encoding gene: mapping of the transcription start point and analysis of the promoter

1994 • 63 citations

The in vivo distribution of oxidized and reduced thioredoxin in Escherichia coli.

1982 • 58 citations

Oxygen Toxicity to the Developing Lung of the Mouse: Role of Reactive Oxygen Species

1996 • 55 citations

The role of redox in the regulation of manganese-containing superoxide dismutase biosynthesis in Escherichia coli.

1988 • 55 citations

Lung manganese superoxide dismutase increases during cytokine-mediated protection against pulmonary oxygen toxicity in rats.

1994 • 53 citations

Sulfhydryl-disulfide modulation and the role of disulfide oxidoreductases in regulation of the catalytic activity of nitric oxide synthase in pulmonary artery endothelial cells.

1995 • 52 citations

Inductions of superoxide dismutases in Escherichia coli under anaerobic conditions. Accumulation of an inactive form of the manganese enzyme.

1988 • 47 citations

Effects of manganese superoxide dismutase on lung fluid balance after smoke inhalation

1995 • 35 citations

Detection of Membrane Associated Thioredoxin on Human Cell Lines

1997 • 33 citations

Regulation of manganese superoxide dismutase in porcine pulmonary artery endothelial cells

1991 • 30 citations

Thioredoxin gene expression is transcriptionally up-regulated by retinol in monkey conducting airway epithelial cells

1992 • 30 citations

Thiol-Modulating Agents Increase Manganese Superoxide Dismutase Activity in Human Lung Fibroblasts

1993 • 16 citations