Crossveinless-2 Controls Bone Morphogenetic Protein Signaling during Early Cardiomyocyte Differentiation in P19 Cells

BMP Induction of Id Proteins Suppresses Differentiation and Sustains Embryonic Stem Cell Self-Renewal in Collaboration with STAT3

2003 • 2,079 citations

Bone morphogenetic proteins: multifunctional regulators of vertebrate development.

1996 • 1,959 citations

Building the mammalian heart from two sources of myocardial cells

2005 • 1,146 citations

Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development

1996 • 959 citations

Teratocarcinomas and embryonic stem cells : a practical approach

1987 • 878 citations

Expression pattern of the mouse T gene and its role in mesoderm formation

1990 • 854 citations

Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite

1998 • 838 citations

Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis.

1995 • 784 citations

Teratocarcinomas and embryonic stem cells: A practical approach

1987 • 768 citations

A role for bone morphogenetic proteins in the induction of cardiac myogenesis.

1997 • 687 citations

ID helix-loop-helix proteins in cell growth, differentiation and tumorigenesis

2000 • 671 citations

DORSAL-VENTRAL PATTERNING AND NEURAL INDUCTION IN XENOPUS EMBRYOS

2004 • 652 citations

A genetic blueprint for cardiac development

2000 • 633 citations

Ascorbic Acid Enhances Differentiation of Embryonic Stem Cells Into Cardiac Myocytes

2003 • 478 citations

Characterization of mesendoderm: a diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture

2005 • 451 citations

Heart development: molecular insights into cardiac specification and early morphogenesis

2003 • 445 citations

Bmp-4 acts as a morphogen in dorsoventral mesoderm patterning in Xenopus

1997 • 332 citations

BMP signaling plays a role in visceral endoderm differentiation and cavitation in the early mouse embryo

1999 • 330 citations

Identification of a BMP‐responsive element in Id1, the gene for inhibition of myogenesis

2002 • 243 citations

MesP1: a novel basic helix-loop-helix protein expressed in the nascent mesodermal cells during mouse gastrulation

1996 • 237 citations

Endoderm and heart development

2000 • 215 citations

BMPER, a Novel Endothelial Cell Precursor-Derived Protein, Antagonizes Bone Morphogenetic Protein Signaling and Endothelial Cell Differentiation

2003 • 214 citations

Role of bone morphogenetic proteins in cardiac differentiation

2006 • 202 citations

BMP-2 induces ectopic expression of cardiac lineage markers and interferes with somite formation in chicken embryos

1998 • 197 citations

Regulation of Avian Cardiac Myogenesis by Activin/TGFβ and Bone Morphogenetic Proteins

1998 • 176 citations

Regionalisation of cell fate and morphogenetic movement of the mesoderm during mouse gastrulation

1995 • 164 citations

Crossveinless 2 contains cysteine-rich domains and is required for high levels of BMP-like activity during the formation of the cross veins in Drosophila

2000 • 163 citations

Smads, Tak1, and Their Common Target Atf-2 Play a Critical Role in Cardiomyocyte Differentiation

2001 • 142 citations

The specification of heart mesoderm occurs during gastrulation in Xenopus laevis

1989 • 125 citations

Phosphatidylinositol 3-Kinase–Akt Pathway Plays a Critical Role in Early Cardiomyogenesis by Regulating Canonical Wnt Signaling

2005 • 122 citations

Essential pro-Bmp roles of crossveinless 2 in mouse organogenesis

2006 • 116 citations

Crossveinless 2 is an essential positive feedback regulator of Bmp signaling during zebrafish gastrulation

2006 • 107 citations

Human Crossveinless-2 is a novel inhibitor of bone morphogenetic proteins

2004 • 73 citations

A vertebrate crossveinless 2 homologue modulates BMP activity and neural crest cell migration

2004 • 60 citations

Mouse Crossveinless-2 is the vertebrate homolog of a Drosophila extracellular regulator of BMP signaling

2002 • 57 citations

BMP signaling in the epiblast is required for proper recruitment of the prospective paraxial mesoderm and development of the somites

2006 • 54 citations

Vertebrate crossveinless 2 is secreted and acts as an extracellular modulator of the BMP signaling cascade

2004 • 39 citations

Parietal endoderm secreted SPARC promotes early cardiomyogenesis in vitro

2005 • 37 citations

BMP induction of cardiogenesis in P19 cells requires prior cell–cell interaction(s)

2006 • 22 citations