Chronic nicotine exposure differentially affects the function of human alpha3, alpha4, and alpha7 neuronal nicotinic receptor subtypes.

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

1993 • 1,455 citations

Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus

1997 • 1,142 citations

Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: A hybridization histochemical study in the rat

1989 • 1,049 citations

Physiological Diversity of Nicotinic Acetylcholine Receptors Expressed by Vertebrate Neurons

1995 • 1,017 citations

Hippocampal synaptic transmission enhanced by low concentrations of nicotine

1996 • 955 citations

A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX

1990 • 923 citations

A subtype of nicotinic cholinergic receptor in rat brain is composed of alpha 4 and beta 2 subunits and is up-regulated by chronic nicotine treatment.

1992 • 858 citations

Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain

1995 • 659 citations

Molecular and Cellular Aspects of Nicotine Abuse

1996 • 605 citations

Pharmacology of Nicotine: Addiction and Therapeutics

1996 • 578 citations

Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I. Pharmacological and functional evidence for distinct structural subtypes.

1993 • 543 citations

Brain α-bungarotoxin binding protein cDNAs and MAbs reveal subtypes of this branch of the ligand-gated ion channel gene superfamily

1990 • 471 citations

Nicotine-induced increase in neuronal nicotinic receptors results from a decrease in the rate of receptor turnover.

1994 • 381 citations

Neuronal Nicotinic Receptor a6 Subunit mRNA is Selectively Concentrated in Catecholaminergic Nuclei of the Rat Brain

1996 • 379 citations

Neuronal Nicotinic Acetylcholine Receptors

1996 • 377 citations

Cigarette smoking and protection from Parkinson's disease

1995 • 372 citations

Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes have a pentameric quaternary structure

1991 • 313 citations

Neurons Can Maintain Multiple Classes of Nicotinic Acetylcholine Receptors Distinguished by Different Subunit Compositions

1995 • 293 citations

Comparative pharmacology of epibatidine: a potent agonist for neuronal nicotinic acetylcholine receptors.

1995 • 284 citations

Immunocytochemical localization of the α7 subunit of the nicotinic acetylcholine receptor in the rat central nervous system

1994 • 247 citations

Nicotine-induced protection of cultured cortical neurons againstN-methyl-D-aspartate receptor-mediated glutamate cytotoxicity

1994 • 240 citations

Role of Ca²⁺Ions in Nicotinic Facilitation of GABA Release in Mouse Thalamus

1997 • 221 citations

Human alpha 7 acetylcholine receptor: cloning of the alpha 7 subunit from the SH-SY5Y cell line and determination of pharmacological properties of native receptors and functional alpha 7 homomers expressed in Xenopus oocytes.

1994 • 210 citations

Homomers of alpha 8 and alpha 7 subunits of nicotinic receptors exhibit similar channel but contrasting binding site properties.

1994 • 207 citations

Synaptic Currents Generated by Neuronal Acetylcholine Receptors Sensitive to α-Bungarotoxin

1996 • 189 citations

Characterization of Nicotinic Acetylcholine Receptors Expressed by Cells of the SH-SY5Y Human Neuroblastoma Clonal Line

1993 • 187 citations

Stable expression, pharmacologic properties and regulation of the human neuronal nicotinic acetylcholine alpha 4 beta 2 receptor.

1996 • 172 citations

Human alpha4beta2 neuronal nicotinic acetylcholine receptor in HEK 293 cells: A patch-clamp study.

1996 • 169 citations

Stable expression and pharmacological properties of the human α7 nicotinic acetylcholine receptor

1995 • 166 citations

Reductions in Acetylcholine and Nicotine Binding in Several Degenerative Diseases

1988 • 141 citations

The kinetic properties of neuronal nicotinic receptors: Genetic basis of functional diversity

1993 • 130 citations

Rapid desensitization of the acute stimulatory effects of nicotine on rat plasma adrenocorticotropin and prolactin.

1986 • 129 citations

Altered Muscarinic and Nicotinic Receptor Densities in Cortical and Subcortical Brain Regions in Parkinson's Disease

1993 • 120 citations

Expression of nicotinic acetylcholine receptor subtypes in brain and retina

1991 • 110 citations

Distribution of nicotinic receptors in cynomolgus monkey brain and ganglia: Localization of α3 subunit mRNA, α-bungarotoxin and nicotine binding sites

1992 • 86 citations

Effects of Chronic Nicotinic Ligand Exposure on Functional Activity of Nicotinic Acetylcholine Receptors Expressed by Cells of the PC12 Rat Pheochromocytoma or the TE671/RD Human Clonal Line

1991 • 81 citations

Effects of chronic administration of nicotine on prolactin release in the rat: inactivation of prolactin response by repeated injections of nicotine.

1990 • 79 citations

Acute effects of nicotine on prolactin release in the rat: agonist and antagonist effects of a single injection of nicotine.

1990 • 68 citations

Pharmacological characterization of alpha-bungarotoxin-sensitive acetylcholine receptors immunoisolated from chick retina: contrasting properties of alpha 7 and alpha 8 subunit-containing subtypes.

1993 • 61 citations

Time-dependent changes in central nicotinic acetylcholine channel kinetics in excised patches

1994 • 44 citations

Are nicotinic receptors activated or inhibited following chronic nicotine treatment?

1996 • 43 citations

Presynaptic nicotinic acetylcholine receptors in the brain

1996 • 40 citations