Neuronal Nicotinic Receptor a6 Subunit mRNA is Selectively Concentrated in Catecholaminergic Nuclei of the Rat Brain

Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.

1988 • 4,617 citations

Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes

1992 • 2,527 citations

Cellular and Molecular Mechanisms of Drug Dependence

1988 • 2,094 citations

The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon

1992 • 1,525 citations

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

1993 • 1,455 citations

Molecular mechanisms of drug addiction

2004 • 1,080 citations

Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: A hybridization histochemical study in the rat

1989 • 1,049 citations

The Diversity of Neuronal Nicotinic Acetylcholine Receptors

1993 • 1,040 citations

Cholinergic systems in mammalian brain and spinal cord

1991 • 942 citations

α9: An acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells

1994 • 869 citations

A subtype of nicotinic cholinergic receptor in rat brain is composed of alpha 4 and beta 2 subunits and is up-regulated by chronic nicotine treatment.

1992 • 858 citations

Efferent connections of the habenular nuclei in the rat

1979 • 824 citations

Mesencephalic dopamine neurons regulate the expression of neuropeptide mRNAs in the rat forebrain.

1986 • 744 citations

Developmental changes in distribution of NMDA receptor channel subunit mRNAs

1992 • 718 citations

Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain

1995 • 659 citations

Both alpha- and beta-subunits contribute to the agonist sensitivity of neuronal nicotinic acetylcholine receptors

1991 • 552 citations

Autoradiographic evidence for nicotine receptors on nigrostriatal and mesolimbic dopaminergic neurons

1985 • 527 citations

Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family.

1987 • 431 citations

Molecular evolution of the nicotinic acetylcholine receptor: An example of multigene family in excitable cells

1995 • 422 citations

Functional contributions of α5 subunit to neuronal acetylcholine receptor channels

1996 • 389 citations

Characterization of Nicotinic Receptor‐Mediated [³H]Dopamine Release from Synaptosomes Prepared from Mouse Striatum

1992 • 352 citations

Developmental regulation of nicotinic ACh receptor subunit mRNAs in the rat central and peripheral nervous systems

1995 • 338 citations

Amino acids of the Torpedo marmorata acetylcholine receptor .alpha. subunit labeled by a photoaffinity ligand for the acetylcholine binding site

1988 • 314 citations

Functional Expression of a New Pharmacological Subtype of Brain Nicotinic Acetylcholine Receptor

1988 • 314 citations

Evidence that mesolimbic dopaminergic activation underlies the locomotor stimulant action of nicotine in rats.

1988 • 313 citations

Neurons assemble acetylcholine receptors with as many as three kinds of subunits while maintaining subunit segregation among receptor subtypes

1993 • 303 citations

The functional diversity of the neuronal nicotinic acetylcholine receptors is increased by a novel subunit: β4

1989 • 294 citations

Evidence for "preterminal" nicotinic receptors on GABAergic axons in the rat interpeduncular nucleus

1993 • 255 citations

The distribution of mRNA encoded by a new member of the neuronal nicotinic acetylcholine receptor gene family (α5) in the rat central nervous system

1990 • 254 citations

Identification of a novel amino acid alpha-tyrosine 93 within the cholinergic ligands-binding sites of the acetylcholine receptor by photoaffinity labeling. Additional evidence for a three-loop model of the cholinergic ligands-binding sites.

1990 • 247 citations

Differential and transient expression of GABAA receptor alpha-subunit mRNAs in the developing rat CNS

1992 • 233 citations

β3: A New Member of Nicotinic Acetylcholine Receptor Gene Family Is Expressed in Brain

1989 • 229 citations

Neurotoxins Distinguish Between Different Neuronal Nicotinic Acetylcholine Receptor Subunit Combinations

1990 • 225 citations

Immunocytochemical localization of a neuronal nicotinic receptor: the beta 2-subunit

1993 • 222 citations

Homomers of alpha 8 and alpha 7 subunits of nicotinic receptors exhibit similar channel but contrasting binding site properties.

1994 • 207 citations

The α5 gene product assembles with multiple acetylcholine receptor subunits to form distinctive receptor subtypes in brain

1992 • 205 citations

The neurobiology of tobacco addiction

1991 • 200 citations

Nicotinic Modulation of [³H]Dopamine Release from Striatal Synaptosomes: Pharmacological Characterisation

1990 • 198 citations

Neurotransmitter-gated ion channels as unconventional allosteric proteins

1994 • 197 citations

Structural and pharmacological characterization of the major brain nicotinic acetylcholine receptor subtype stably expressed in mouse fibroblasts.

1991 • 196 citations

Gene transcripts for the nicotinic acetylcholine receptor subunit, beta4, are distributed in multiple areas of the rat central nervous system

1992 • 195 citations

Existence of different subtypes of nicotinic acetylcholine receptors in the rat habenulo-interpeduncular system

1991 • 193 citations

Organization of choline acetyltransferase-containing structures in the forebrain of the rat

1986 • 174 citations

Functional Contribution of Neuronal AChR Subunits Revealed by Antisense Oligonucleotides

1991 • 164 citations

Identification of a New Component of the Agonist Binding Site of the Nicotinic α7 Homooligomeric Receptor

1995 • 147 citations

Distribution of Nicotinic Receptors in the Human Hippocampus and Thalamus

1994 • 136 citations

Choline acetyltransferase immunoreactivity in the rat thalamus

1987 • 134 citations

Topography of cholinergic and substance P pathways in the habenulo-interpeduncular system of the rat. An immunocytochemical and microchemical approach

1987 • 132 citations

Pharmacological characterization of neuronal acetylcholine gated ion channel receptor-mediated hippocampal norepinephrine and striatal dopamine release from rat brain slices.

1995 • 126 citations

Effects of nicotine on the release of 3H-noradrenaline from the hypothalamus

1972 • 121 citations

Mapping of brain areas expressing RNA homologous to two different acetylcholine receptor alpha-subunit cDNAs.

1986 • 112 citations

Expression of Neuronal Nicotinic Acetylcholine Receptor Subunit Genes in the Rat Autonomic Nervous System

1994 • 108 citations

A novel type of nicotinic receptor in the rat central nervous system characterized by patch-clamp techniques

1990 • 107 citations

Origin, course and termination of the mesohabenular dopamine pathway in the rat

1984 • 97 citations

[43] Molecular hybridization of immobilized nucleic acids: Theoretical concepts and practical considerations

1987 • 96 citations

Nicotine-induced release of catecholamines from rat hippocampus and striatum

1978 • 93 citations

Innervation and target tissue interactions differentially regulate acetylcholine receptor subunit mRNA levels in developing neurons in situ

1995 • 84 citations

Neuronal bungarotoxin blocks the nicotinic stimulation of endogenous dopamine release from rat striatum

1989 • 82 citations

Effects of nicotine on distribution and release of 14C-norepinephrine and 14C-dopamine in rat brain striatum and hypothalamus slices

1974 • 78 citations

Ligand-gated ion channels

1990 • 59 citations

In situ hybridization protocols for the brain

2004 • 51 citations

Different postnatal development profiles of neurons containing distinct GABA_A receptor β subunit mRNAs (β₁, β₂, and β₃) in the rat forebrain

1991 • 50 citations

Heterogeneity of neuronal nicotinic acetylcholine receptors in thin slices of rat medial habenula.

1995 • 47 citations

Expression of neuronal acetylcholine nicotinic receptor ?4 and ?2 subunits during postnatal development of the rat brain

1995 • 38 citations