Molecular and Cellular Aspects of Nicotine Abuse

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

1996 • 2,452 citations

Drugs of abuse: anatomy, pharmacology and function of reward pathways

1992 • 2,091 citations

Mortality from tobacco in developed countries: indirect estimation from national vital statistics

1992 • 1,416 citations

Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: A hybridization histochemical study in the rat

1989 • 1,049 citations

Physiological Diversity of Nicotinic Acetylcholine Receptors Expressed by Vertebrate Neurons

1995 • 1,017 citations

The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine

1992 • 827 citations

Inhibition of monoamine oxidase B in the brains of smokers

1996 • 666 citations

Acetylcholine Receptor: An Allosteric Protein

1984 • 620 citations

Nicotine maintains robust self-administration in rats on a limited-access schedule

1989 • 586 citations

Nicotine binding and nicotinic receptor subunit RNA after chronic nicotine treatment

1992 • 540 citations

Nicotine-induced increase in neuronal nicotinic receptors results from a decrease in the rate of receptor turnover.

1994 • 381 citations

Higher levels of nicotine in arterial than in venous blood after cigarette smoking

1993 • 374 citations

The paradox of nicotinic acetylcholine receptor upregulation by nicotine

1990 • 350 citations

Nicotinic excitation of rat ventral tegmental neurones in vitro studied by intracellular recording

1989 • 291 citations

The neurobiology of tobacco addiction

1991 • 200 citations

Downregulation of nicotinic receptor function after chronic nicotine infusion.

1993 • 181 citations

Nicotine-induced place preferences following prior nicotine exposure in rats

1994 • 154 citations

Cyclic AMP regulates the proportion of functional acetylcholine receptors on chicken ciliary ganglion neurons.

1987 • 131 citations

Chapter 27 Nicotine dependence and tolerance in man: pharmacokinetic and pharmacodynamic investigations

1989 • 96 citations

Addictive Drugs: The Cigarette Experience

1992 • 88 citations

Reinforcing effects of nicotine in humans and experimental animals responding under intermittent schedules of IV drug injection

1988 • 88 citations

Effects of chronic administration of nicotine on prolactin release in the rat: inactivation of prolactin response by repeated injections of nicotine.

1990 • 79 citations

Chapter 28 Subjective and behavioural effects of nicotine in humans: some sources of individual variation

1989 • 63 citations

Time-dependent changes in central nicotinic acetylcholine channel kinetics in excised patches

1994 • 44 citations

The Mesolimbic Dopamine System as a Target for Nicotine

1991 • 11 citations