Genetic linkage and complex diseases, with special reference to psychiatric disorders

Lifetime Prevalence of Specific Psychiatric Disorders in Three Sites

1984 • 2,591 citations

A polymorphic DNA marker genetically linked to Huntington's disease

1983 • 2,329 citations

Localization of the gene for familial adenomatous polyposis on chromosome 5

1987 • 1,386 citations

The Genetics of Human Populations

1972 • 1,252 citations

The Genetic Defect Causing Familial Alzheimer's Disease Maps on Chromosome 21

1987 • 1,149 citations

Bipolar affective disorders linked to DNA markers on chromosome 11

1987 • 826 citations

Psychiatric Disorders in Foster Home Reared Children of Schizophrenic Mothers

1966 • 786 citations

A highly polymorphic DNA marker linked to adult polycystic kidney disease on chromosome 16

1985 • 715 citations

Gene for von Recklinghausen Neurofibromatosis Is in the Pericentromeric Region of Chromosome 17

1987 • 691 citations

The Gene for Familial Polyposis Coli Maps to the Long Arm of Chromosome 5

1987 • 683 citations

Localization of a susceptibility locus for schizophrenia on chromosome 5

1988 • 624 citations

A polygenic theory of schizophrenia.

1967 • 622 citations

Assessing the role of HLA-linked and unlinked determinants of disease.

1987 • 548 citations

Genetic linkage of bilateral acoustic neurofibromatosis to a DNA marker on chromosome 22

1987 • 470 citations

Analysis of deletions in DNA from patients with Becker and Duchenne muscular dystrophy

1986 • 468 citations

A linked genetic marker for multiple endocrine neoplasia type 2A on chromosome 10

1987 • 440 citations

The detection and estimation of linkage between the genes for elliptocytosis and the Rh blood type.

1956 • 434 citations

Genetic research in psychiatry

1976 • 434 citations

Assignment of multiple endocrine neoplasia type 2A to chromosome 10 by linkage

1987 • 423 citations

Evidence against linkage of schizophrenia to markers on chromosome 5 in a northern Swedish pedigree

1988 • 394 citations

Genetic linkage of von Recklinghausen neurofibromatosis to the nerve growth factor receptor gene

1987 • 379 citations

Overview: a current perspective on twin studies of schizophrenia

1983 • 315 citations

Population genetic studies of retinitis pigmentosa.

1980 • 298 citations

Three Recessive Loci Required for Insulin-Dependent Diabetes in Nonobese Diabetic Mice

1987 • 293 citations

Amish Study, I: Affective disorders among the Amish, 1976-1980

1983 • 292 citations

The transmission of schizophrenia under a multifactorial threshold model.

1983 • 256 citations

Molecular genetic evidence for heterogeneity in manic depression

1987 • 252 citations

Absence of Linkage of Chromosome 21q21 Markers to Familial Alzheimer's Disease

1988 • 245 citations

Close linkage of c-Harvey-ras-1 and the insulin gene to affective disorder is ruled out in three North American pedigrees

1987 • 223 citations

The Pittsburgh Study of Insulin-Dependent Diabetes Mellitus: Risk for Diabetes Among Relatives of IDDM

1982 • 217 citations

An Independent Analysis of the Danish Adoption Study of Schizophrenia

1984 • 212 citations

Family History Studies: V. The Genetics of Mania

1969 • 211 citations

Frequency in relatives for an all‐or‐none trait

1971 • 180 citations

Genetics, chance, and morphogenesis.

1987 • 172 citations

Linkage studies with X-chromosome markers in bipolar (manic-depressive) and unipolar (depressive) illnesses.

1974 • 166 citations

Linkage of cystic fibrosis to two tightly linked DNA markers: joint report from a collaborative study.

1986 • 165 citations

Schizophrenia in a North Swedish geographical isolate, 1900–1977. Epidemiology, genetics and biochemistry

1978 • 150 citations

Neurofibromatosis—phenotype, natural history and pathogenesis

1987 • 143 citations

Evidence for X-Linkage in the Transmission of Manic-Depressive Illness

1972 • 142 citations

Psychiatric syndromes linked to reproductive function in women: a review of current knowledge

1989 • 139 citations

The Pittsburgh Insulin-dependent Diabetes Mellitus (IDDM) Registry: The Incidence of Insulin-dependent Diabetes Mellitus in Allegheny County, Pennsylvania (1965–1976)

1981 • 137 citations

Relatives at risk for mental disorder

1990 • 124 citations

Color Blindness Not Closely Linked to Bipolar Illness

1979 • 116 citations

Genetic Factors in `Schizophrenia'

1973 • 109 citations

Hereditary Elliptocytosis and Related Disorders

1985 • 102 citations

Segregation analysis of schizophrenia and related disorders.

1984 • 101 citations

Color Blindness Linkage to Bipolar Manic-Depressive Illness

1979 • 98 citations

An analysis of the genetics of schizophrenia

1973 • 87 citations

Schizophrenic Illness in the Families of Schizophrenic Adoptees: Findings From the Danish National Sample

1988 • 81 citations

Splitting schizophrenia

1988 • 76 citations

Linkage analysis under “random” and “genetic” reduced penetrance

1989 • 70 citations

A Family-Genetic Study of Dementia of Alzheimer Type

1988 • 59 citations

Some epistatic two-locus models of disease. II. The confounding of linkage and association.

1981 • 55 citations

Power of the affected‐sib‐pair method to detect disease susceptibility loci of small effect: An application to multiple sclerosis

1982 • 44 citations

An investigation into the fertility rates of mentally ill patients

1963 • 37 citations

Where next with psychiatric illness?

1988 • 34 citations

Partly Dominant Transmission of Schizophrenia in Iceland

1988 • 32 citations

Annual Review of the Schizophrenic Syndrome, Vol. 3: 1973

1975 • 5 citations