Genetics, chance, and morphogenesis.

Construction of a genetic linkage map in man using restriction fragment length polymorphisms.

1980 • 8,270 citations

Mutation and Cancer: Statistical Study of Retinoblastoma

1971 • 7,335 citations

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

1983 • 1,952 citations

A Human Syndrome Caused by Immotile Cilia

1976 • 1,235 citations

The Genetic Defect Causing Familial Alzheimer's Disease Maps on Chromosome 21

1987 • 1,149 citations

A STOCHASTIC MODEL OF STEM CELL PROLIFERATION, BASED ON THE GROWTH OF SPLEEN COLONY-FORMING CELLS

1964 • 889 citations

Do Cells Cycle?

1973 • 885 citations

Loss of heterozygosity in three embryonal tumours suggests a common pathogenetic mechanism

1985 • 555 citations

Commitment to erythroid differentiation by friend erythroleukemia cells: a stochastic analysis

1976 • 374 citations

Multifactorial Inheritance Hypothesis for the Etiology of Congenital Heart Diseases

1968 • 313 citations

Homozygosity of Chromosome 13 in Retinoblastoma

1984 • 294 citations

Intraclonal Variation in Proliferative Potential of Human Diploid Fibroblasts: Stochastic Mechanism for Cellular Aging

1980 • 290 citations

Random determination of a developmental process: Reversal of normal visceral asymmetry in the mouse

1976 • 237 citations

Disparate differentiation in mouse hemopoietic colonies derived from paired progenitors.

1984 • 233 citations

Dominant Inheritance of Adenomatous Colonic Polyps and Colorectal Cancer

1985 • 231 citations

GENETICAL STUDIES ON HUMAN RED CELL ACID PHOSPHATASE.

1964 • 204 citations

THE SIMULATION OF MENDELISM

1960 • 201 citations

Cell adhesion and morphogenesis: the regulator hypothesis.

1984 • 189 citations

Mouse major histocompatibility class I gene expression begins at midsomite stage and is inducible in earlier-stage embryos by interferon.

1985 • 185 citations

Frequency in relatives for an all‐or‐none trait

1971 • 180 citations

The genetic transmission of schizophrenia: Application of Mendelian latent structure analysis to eye tracking dysfunctions in schizophrenia and affective disorder

1986 • 165 citations

Testing the Commitment Theory of Cellular Aging

1977 • 154 citations

Regulation of human fibroblast growth rate by both noncycling cell fraction transition probability is shown by growth in 5-bromodeoxyuridine followed by Hoechst 33258 flow cytometry.

1983 • 121 citations

The inheritance of common congenital malformations.

1965 • 119 citations

Ectopia cordis and cleft sternum: Evidence for mechanical teratogenesis following rupture of the chorion or yolk sac

1985 • 113 citations

A differential adhesion approach to the patterning of nerve connections

1980 • 112 citations

Familial clustering of situs inversus totalis, and asplenia and polysplenia syndromes

1983 • 104 citations

Probable autosomal recessive inheritance of polysplenia, situs inversus and cardiac defects in an Amish family

1983 • 100 citations

THE GENETICAL BACKGROUND OF COMMON DISEASES

1953 • 91 citations

Chance, necessity and antibody gene dynamics

1983 • 87 citations

Increased adhesiveness of trisomy 21 cells and atrioventricular canal malformations in down syndrome: A stochastic model

1985 • 76 citations

Recurrence risks for multifactorial inheritance.

1971 • 75 citations

Etiology of Ventricular Septal Defects: An Epidemiologic Approach

1985 • 53 citations

Cancer biology: Recessive mutation in aetiology of Wilms' tumour

1984 • 52 citations

Increased adhesiveness of Down syndrome fetal fibroblasts in vitro.

1984 • 51 citations

Stochastic expression of fetal hemoglobin in adult erythroid cells.

1981 • 43 citations

The fusion of dorsal and ventral endocardial cushions in the embryonic chick heart: A study in fine structure

1972 • 35 citations

Pathology of Trisomy 21 — with Particular Reference to Persistent Common Atrioventricular Canal of the Heart

1981 • 33 citations

Stochastic branching model for hemopoietic progenitor cell differentiation

1985 • 25 citations

Enlargement of the membanous ventricular septum: An internal stigma of Down's syndrome

1974 • 23 citations