Behavioral Evidence of Depolarization Block of Dopamine Neurons after Chronic Treatment with Haloperidol and Clozapine

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

AChE-stained horizontal sections of the rat brain in stereotaxic coordinates

1980 • 4,422 citations

Brain Dopamine and Reward

1989 • 1,899 citations

Antischizophrenic Drugs: Chronic Treatment Elevates Dopamine Receptor Binding in Brain

1977 • 1,017 citations

Addictive Drugs and Brain Stimulation Reward

1996 • 777 citations

Typical and atypical neuroleptics: differential effects of chronic administration on the activity of A9 and A10 midbrain dopaminergic neurons

1983 • 680 citations

Differential Effects of Classical and Atypical Antipsychotic Drugs on A9 and A10 Dopamine Neurons

1983 • 589 citations

Acute and chronic haloperidol treatment: Comparison of effects on nigral dopaminergic cell activity

1978 • 550 citations

Dopamine Auto- and Postsynaptic Receptors: Electrophysiological Evidence for Differential Sensitivity to Dopamine Agonists

1979 • 502 citations

Induction of depolarization block in midbrain dopamine neurons by repeated administration of haloperidol: analysis using in vivo intracellular recording.

1986 • 309 citations

Dopamine-cell depolarization block as a model for the therapeutic actions of antipsychotic drugs

1997 • 284 citations

The curve-shift paradigm in self-stimulation

1986 • 250 citations

Occupancy of central neurotransmitter receptors by risperidone, clozapine and haloperidol, measured ex vivo by quantitative autoradiography

1993 • 225 citations

Comparison of the effects of chronic haloperidol treatment on A9 and A10 dopamine neurons in the rat

1983 • 212 citations

Possible mechanisms by which repeated clozapine administration differentially affects the activity of two subpopulations of midbrain dopamine neurons

1985 • 196 citations

Activity of A9 and A10 dopaminergic neurons in unrestrained rats: further characterization and effects of apomorphine and cholecystokinin

1987 • 164 citations

Pimozide and amphetamine have opposing effects on the reward summation function

1984 • 156 citations

Quantitative determination of the effects of catecholaminergic agonists and antagonists on the rewarding efficacy of brain stimulation

1987 • 113 citations

Low doses of apomorphine elicit two opposing influences on dopamine cell electrophysiology

1985 • 101 citations

Chronic treatment with clozapine, unlike haloperidol, does not induce changes in striatal D-2 receptor function in the rat

1985 • 93 citations

Differential alterations in striatal dopamine receptor sensitivity induced by repeated administration of clinically equivalent doses of haloperidol, sulpiride or clozapine in rats

1984 • 69 citations

Changes in sensitivity of release modulating dopamine autoreceptors after chronic treatment with haloperidol.

1983 • 61 citations

Differential effects after repeated treatment with haloperidol, clozapine, thioridazine and tefludazine on SNC and VTA dopamine neurones in rats

1988 • 58 citations

Electrophysiological, biochemical, and behavioral studies of acute haloperidol-induced depolarization block of nigral dopamine neurons

1992 • 54 citations

Alterations in dopamine metabolism after chronic administration of haloperidol

1985 • 44 citations

Depolarization inactivation of dopamine neurons: an artifact?

1995 • 41 citations

Inhibition of nigral dopamine neurons by systemic and local apomorphine: Possible contribution of dendritic autoreceptors

1992 • 40 citations

Behavioral evidence for midbrain dopamine depolarization inactivation

1989 • 39 citations

A comparison of striatal and mesolimbic dopamine function in the rat during 6-month trifluoperazine administration

1980 • 36 citations

Electrophysiological evidence that a subset of midbrain dopamine neurons integrate the reward signal induced by electrical stimulation of the posterior mesencephalon

1998 • 34 citations

Enhancement of self-stimulation behavior in rats and monkeys after chronic neuroleptic treatment: Evidence for mesolimbic supersensitivity

1979 • 33 citations

The distribution of apomorphine in rat brain: possible behavioral correlates.

1978 • 25 citations

Apomorphine and electrical self-stimulation of rat brain

1992 • 24 citations

Failure of chronic haloperidol to induce depolarization inactivation of dopamine neurons in unanesthetized rats

1994 • 23 citations

Haloperidol does not produce dopamine cell depolarization-block in paralyzed, unanesthetized rats

1998 • 22 citations

Comparison of short-term administration of sertindole, clozapine and haloperidol on the inactivation of midbrain dopamine neurons in the rat

1994 • 20 citations

The effects of some atypical neuroleptics on apomorphine-induced behaviors as a measure of their relative potencies in blocking presynaptic versus postsynaptic dopamine receptors

1986 • 14 citations

Clozapine's functional mesolimbic selectivity is not duplicated by the addition of anticholinergic action to haloperidol: a brain stimulation study in the rat

1993 • 14 citations

Increase in D2 dopamine receptors in the substantia nigra after chronic (−)-sulpiride treatment

1991 • 12 citations

Effect of pimozide on self-stimulation thresholds under a continuous and fixed-interval schedule of reinforcement

1996 • 11 citations

Anatomically Selective Action of Atypical Neuroleptics on the Mesocorticolimbic Dopamine System

1988 • 11 citations

Behavioural Manifestations Elicited by Apomorphine, Influence of the Route of Administration

1989 • 11 citations

Behavioral evidence of depolarization block of mesencephalic dopamine neurons by acute haloperidol in partially 6-hydroxydopamine-lesioned rats.

1991 • 10 citations

Behavioral evidence of depolarization block of mesencephalic dopamine neurons by acute haloperidol in partially 6-hydroxydopamine-lesioned rats.

1991 • 9 citations