Possible mechanisms by which repeated clozapine administration differentially affects the activity of two subpopulations of midbrain dopamine neurons

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1964 • 1,002 citations

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1974 • 832 citations

Acute and chronic haloperidol treatment: Comparison of effects on nigral dopaminergic cell activity

1978 • 550 citations

Relationship of neuroleptic drug effects at brain dopamine, serotonin, alpha-adrenergic, and histamine receptors to clinical potency

1980 • 543 citations

Anti-muscarinic properties of neuroleptics and drug-induced Parkinsonism

1974 • 382 citations

Evidence for the absence of impulse-regulating somatodendritic and synthesis-modulating nerve terminal autoreceptors on subpopulations of mesocortical dopamine neurons

1984 • 312 citations

Effect of clozapine on the turnover of dopamine in the corpus striatum and in the limbic system

1973 • 296 citations

Understanding and Treating Tardive Dyskinesia

1983 • 269 citations

Intracellular and extracellular electrophysiology of nigral dopaminergic neurons—2. Action potential generating mechanisms and morphological correlates

1983 • 227 citations

Comparison of the effects of chronic haloperidol treatment on A9 and A10 dopamine neurons in the rat

1983 • 212 citations

A Metachromatic Stain for Neural Tissue

1974 • 165 citations

Proglumide: Selective Antagonism of Excitatory Effects of Cholecystokinin in Central Nervous System

1983 • 154 citations

Effects of clozapine on cerebral catecholaminergic neurone systems

1972 • 126 citations

Effect of single and repeated administration of clozapine on the metabolism of dopamine and noradrenaline in the brain of the rat

1974 • 96 citations

The effects of antipsychotics on the turnover rate of GABA and acetylcholine in rat brain nuclei

1976 • 87 citations

The Clinical Use of Anticholinergic Drugs As Treatment for Extrapyramidal Side Effects of Neuroleptic Drugs

1983 • 83 citations

Amantadine versus trihexyphenidyl in the treatment of neuroleptic- induced parkinsonism

1976 • 71 citations

The need for continuous use of antiparkinsonian medication with chronic schizophrenic patients receiving long-term neuroleptic therapy

1981 • 47 citations

Effects of clozapine on the activity of central dopaminergic and noradrenergic neurons

1979 • 41 citations

Biological Aspects of Mental Disorder

1980 • 40 citations

Mechanisms underlying tardive dyskinesia.

1976 • 29 citations

Identification of direct competition for, and indirect influences on, striatal muscarinic cholinergic receptors: in vivo [3H]Quinuclidinyl benzilate binding in rats

1979 • 27 citations

Pathophysiologic basis of tardive dyskinesia.

1980 • 20 citations

Behavioral and biochemical correlates after haloperidol and clozapine long-term treatment.

1980 • 16 citations

Combined treatment of tardive dyskinesia with clonidine and neuroleptics: A follow-up study of three cases for three years

1983 • 15 citations

Therapeutic approaches to neuroleptic-induced tardive dyskinesias.

1976 • 14 citations