Assemblage of the prespliceosome complex with separated fractions isolated from HeLa cells.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

A compensatory base change in U1 snRNA suppresses a 5′ splice site mutation

1986 • 755 citations

A factor, U2AF, is required for U2 snRNP binding and splicing complex assembly

1988 • 535 citations

Interactions between small nuclear ribonucleoprotein particles in formation of spliceosomes

1987 • 530 citations

Stepwise assembly of a pre-mRNA splicing complex requires U-snRNPs and specific intron sequences

1985 • 524 citations

Electrophoretic separation of complexes involved in the splicing of precursors to mRNAs

1986 • 490 citations

A multicomponent complex is involved in the splicing of messenger RNA precursors

1985 • 451 citations

The "Spliceosome": Yeast Pre-Messenger RNA Associates with a 40 S Complex in a Splicing-Dependent Reaction

1985 • 421 citations

The 5′ terminus of the RNA moiety of U1 small nuclear ribonucleoprotein particles is required for the splicing of messenger RNA precursors

1984 • 404 citations

Spliceosome assembly in yeast.

1987 • 402 citations

A protein associated with small nuclear ribonucleoprotein particles recognizes the 3′ splice site of premessenger RNA

1986 • 283 citations

A protein that specifically recognizes the 3′ splice site of mammalian pre-mRNA introns is associated with a small nuclear ribonucleoprotein

1986 • 274 citations

An ordered pathway of snRNP binding during mammalian pre-mRNA splicing complex assembly.

1987 • 272 citations

An Early Hierarchic Role of U1 Small Nuclear Ribonucleoprotein in Spliceosome Assembly

1988 • 271 citations

Affinity Chromatography of Splicing Complexes: U2, U5, and U4 + U6 Small Nuclear Ribonucleoprotein Particles in the Spliceosome

1986 • 238 citations

Gel electrophoretic isolation of splicing complexes containing U1 small nuclear ribonucleoprotein particles.

1988 • 183 citations

Presplicing complex formation requires two proteins and U2 snRNP.

1988 • 117 citations

Pre-mRNA splicing by complementation with purified human UI, U2, U4/U6 and U5 snRNPs

1988 • 112 citations

Ribonucleoprotein Complex Formation During Pre-mRNA Splicing in Vitro

1986 • 93 citations

RNA splicing products formed with isolated fractions from HeLa cells are associated with fast-sedimenting complexes.

1986 • 75 citations

RNA-protein organization of U1, U5 and U4-U6 small nuclear ribonucleoproteins in HeLa cells

1986 • 62 citations

Isolation and characterization of two fractions from HeLa cells required for mRNA splicing in vitro.

1985 • 51 citations

Alterations in the Polypyrimidine Sequence Affect the in vitro Splicing Reactions Catalyzed by HeLa cell-Free Preparations

1989 • 28 citations

Interaction of snRNAs with rapidly sedimenting nuclear sub-structures (hnRNPs) from HeLa cells

1983 • 27 citations