Ribonucleoprotein Complex Formation During Pre-mRNA Splicing in Vitro

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

The structure and evolution of the human β-globin gene family

1980 • 1,398 citations

Are snRNPs involved in splicing?

1980 • 1,206 citations

Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus

1979 • 1,178 citations

Ovalbumin gene: evidence for a leader sequence in mRNA and DNA sequences at the exon-intron boundaries.

1978 • 1,117 citations

Excision of an intact intron as a novel lariat structure during pre-mRNA splicing in vitro

1984 • 761 citations

Normal and mutant human β-globin pre-mRNAs are faithfully and efficiently spliced in vitro

1984 • 679 citations

The U1 small nuclear RNA-protein complex selectively binds a 5′ splice site in vitro

1983 • 593 citations

U2 as well as U1 small nuclear ribonucleoproteins are involved in premessenger RNA splicing

1985 • 568 citations

Stepwise assembly of a pre-mRNA splicing complex requires U-snRNPs and specific intron sequences

1985 • 524 citations

The nucleotide sequence of the human β-globin gene

1980 • 502 citations

Lariat RNA's as Intermediates and Products in the Splicing of Messenger RNA precursors

1984 • 474 citations

A multicomponent complex is involved in the splicing of messenger RNA precursors

1985 • 451 citations

Multiple factors including the small nuclear ribonucleoproteins U1 and U2 are necessary for Pre-mRNA splicing in vitro

1985 • 442 citations

The "Spliceosome": Yeast Pre-Messenger RNA Associates with a 40 S Complex in a Splicing-Dependent Reaction

1985 • 421 citations

The 5′ terminus of the RNA moiety of U1 small nuclear ribonucleoprotein particles is required for the splicing of messenger RNA precursors

1984 • 404 citations

Intron sequences involved in lariat formation during pre-mRNA splicing

1985 • 402 citations

Lariat structures are in vivo intermediates in yeast pre-mRNA splicing

1984 • 379 citations

Splicing of messenger RNA precursors is inhibited by antisera to small nuclear ribonucleoprotein

1983 • 333 citations

The 3′ Splice Site of Pre-Messenger RNA Is Recognized by a Small Nuclear Ribonucleoprotein

1985 • 310 citations

The Structure and Evolution of the Human /?-Globin Gene Family

1980 • 301 citations

An RNA Processing Activity That Debranches RNA Lariats

1985 • 300 citations

Messenger RNA splicing in vitro: An excised intervening sequence and a potential intermediate

1984 • 262 citations

Splicing of in vitro synthesized messenger RNA precursors in HeLa cell extracts

1983 • 255 citations

Characterization of the branch site in lariat RNAs produced by splicing of mRNA precursors

1985 • 232 citations

In vivo splicing products of the rabbit β-globin pre-mRNA

1984 • 209 citations

BKV splice sequences based on analysis of preferred donor and acceptor sites

1979 • 198 citations

Role of the 3′ splice site consensus sequence in mammalian pre-mRNA splicing

1985 • 184 citations

Specific and stable intron-factor interactions are established early during in vitro pre-mRNA splicing

1985 • 180 citations

Splicing of adenovirus RNA in a cell-free transcription system.

1983 • 159 citations

In vivo characterization of yeast mRNA processing intermediates

1984 • 152 citations

Simple, efficientin vitrosynthesis of capped RNA useful for direct expression of cloned eukaryoti genes

1982 • 152 citations

Micro thin-layer techniques for rapid sequence analysis of 32P-labeled RNA: Double digestion and pancreatic ribonuclease analyses

1977 • 135 citations

Polyadenylylated nuclear RNA contains branches

1983 • 120 citations

Cofactor requirements of splicing of purified messenger RNA precursors

1984 • 82 citations

Structural and functional defects in beta-thalassemia.

1983 • 14 citations