IL-17 Enhances the Net Angiogenic Activity and In Vivo Growth of Human Non-Small Cell Lung Cancer in SCID Mice through Promoting CXCR-2-Dependent Angiogenesis

Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis

1996 • 6,878 citations

Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma

1991 • 5,657 citations

Interleukin-8 as a Macrophage-Derived Mediator of Angiogenesis

1992 • 2,130 citations

Induction of angiogenesis during the transition from hyperplasia to neoplasia

1989 • 1,912 citations

Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression

1995 • 1,863 citations

Interleukin-23 Promotes a Distinct CD4 T Cell Activation State Characterized by the Production of Interleukin-17

2003 • 1,828 citations

IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis

1999 • 1,660 citations

T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines.

1996 • 1,496 citations

The cytokine handbook

1994 • 1,121 citations

Human IL-17: a novel cytokine derived from T cells.

1995 • 1,014 citations

Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor

1995 • 991 citations

IL-17 stimulates the production and expression of proinflammatory cytokines, IL-beta and TNF-alpha, by human macrophages.

1998 • 954 citations

IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines

2001 • 928 citations

IL-17 Stimulates the Production and Expression of Proinflammatory Cytokines, IL-β and TNF-α, by Human Macrophages

1998 • 810 citations

Interleukin-17 promotes angiogenesis and tumor growth

2002 • 795 citations

CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene.

1993 • 751 citations

Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo.

1995 • 710 citations

Microbial Lipopeptides Induce the Production of IL-17 in Th Cells

2000 • 589 citations

The CXC Chemokine Receptor 2, CXCR2, Is the Putative Receptor for ELR+ CXC Chemokine-Induced Angiogenic Activity

2000 • 565 citations

Interleukin-17 and Interferon-γ Synergize in the Enhancement of Proinflammatory Cytokine Production by Human Keratinocytes

1998 • 565 citations

IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding

2001 • 532 citations

IL-17 Is Produced by Some Proinflammatory Th1/Th0 Cells But Not by Th2 Cells

1999 • 415 citations

Inhibition of interleukin-8 reduces tumorigenesis of human non-small cell lung cancer in SCID mice.

1996 • 405 citations

Inhibition of interleukin 8 attenuates angiogenesis in bronchogenic carcinoma.

1994 • 373 citations

Interferon-gamma-inducible protein 10 (IP-10) is an angiostatic factor that inhibits human non-small cell lung cancer (NSCLC) tumorigenesis and spontaneous metastases.

1996 • 358 citations

Structure and neutrophil-activating properties of a novel inflammatory peptide (ENA-78) with homology to interleukin 8.

1991 • 349 citations

Cutting Edge: IL-17F, a Novel Cytokine Selectively Expressed in Activated T Cells and Monocytes, Regulates Angiogenesis and Endothelial Cell Cytokine Production

2001 • 340 citations

IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis

2001 • 328 citations

Tumor Cell Responses to IFNγ Affect Tumorigenicity and Response to IL-12 Therapy and Antiangiogenesis

1998 • 324 citations

Vascular endothelial growth factor is associated with neovascularization and influences progression of non-small cell lung carcinoma.

1997 • 305 citations

Evidence for a Role of IL-17 in Organ Allograft Rejection: IL-17 Promotes the Functional Differentiation of Dendritic Cell Progenitors

1999 • 297 citations

Expression of the cytokine RANTES in human rheumatoid synovial fibroblasts. Differential regulation of RANTES and interleukin-8 genes by inflammatory cytokines.

1993 • 296 citations

Interleukin 17, a T-cell-derived cytokine, promotes tumorigenicity of human cervical tumors in nude mice.

1999 • 291 citations

Depletion of CXCR2 Inhibits Tumor Growth and Angiogenesis in a Murine Model of Lung Cancer

2004 • 284 citations

MOLECULAR CHARACTERIZATION OF THE HUMAN INTERLEUKIN (Il)-17 RECEPTOR

1997 • 282 citations

The expression of a gamma interferon-induced protein (IP-10) in delayed immune responses in human skin.

1987 • 274 citations

Epithelial-neutrophil activating peptide (ENA-78) is an important angiogenic factor in non-small cell lung cancer.

1998 • 259 citations

Mig, the Monokine Induced By Interferon-γ, Promotes Tumor Necrosis In Vivo

1997 • 251 citations

Role of C-X-C chemokines as regulators of angiogenesis in lung cancer

1995 • 250 citations

Expression and function of pro‐inflammatory interleukin IL‐17 and IL‐17 receptor in normal, benign hyperplastic, and malignant prostate

2003 • 230 citations

Cytokine networks in solid human tumors: regulation of angiogenesis

1994 • 209 citations

Differential Antitumor Effects of Administration of Recombinant IL-18 or Recombinant IL-12 Are Mediated Primarily by Fas-Fas Ligand- and Perforin-Induced Tumor Apoptosis, Respectively

1999 • 199 citations

Growth Regulated Oncogene-α expression by murine squamous cell carcinoma promotes tumor growth, metastasis, leukocyte infiltration and angiogenesis by a host CXC Receptor-2 dependent mechanism

2000 • 176 citations

The role of CXC chemokines in the regulation of angiogenesis in non-small cell lung cancer

1997 • 161 citations

Expression of IL-17 mRNA in Ovarian Cancer

2001 • 153 citations

Expression of angiopoietins and its clinical significance in non-small cell lung cancer.

2002 • 151 citations

Interleukin-17 enhances bFGF-, HGF- and VEGF-induced growth of vascular endothelial cells

2004 • 146 citations

IL-17 Expression in Human Herpetic Stromal Keratitis: Modulatory Effects on Chemokine Production by Corneal Fibroblasts

2002 • 133 citations

Interleukin-17 augments tumor necrosis factor-α-induced elaboration of proangiogenic factors from fibroblasts

2004 • 123 citations

Expression and activity of IL‐17 in cutaneous T‐cell lymphomas (mycosis fungoides and sezary syndrome)

2004 • 112 citations

Interferon-α and interferon-γ down-regulate the production of interleukin-8 and ENA-78 in human monocytes

1995 • 105 citations

Expression in lung carcinomas of platelet-derived growth factor and its receptors.

1997 • 98 citations

IL-2 up-regulates but IFN-gamma suppresses IL-8 expression in human monocytes.

1993 • 88 citations

Constitutive expression of interferon gamma-inducible protein 10 in lymphoid organs and inducible expression in T cells and thymocytes.

1994 • 83 citations

Anti-tumor angiogenesis therapy using soluble receptors: enhanced inhibition of tumor growth when soluble fibroblast growth factor receptor-1 is used with soluble vascular endothelial growth factor receptor

2002 • 78 citations

Stromal-Derived Factor-1α/CXCL12-CXCR 4 Axis Is Involved in the Dissemination of NSCLC Cells into Pleural Space

2003 • 73 citations

Co-expression of epidermal growth factor receptor and transforming growth factor-α is independent of ras mutations in lung adenocarcinoma

2000 • 68 citations

Expression of IP-10, a lipopolysaccharide- and interferon-gamma-inducible protein, in murine mesangial cells in culture.

1993 • 54 citations

Simultaneous quantification of prostaglandins in human synovial cell-cultured medium using liquid chromatography/tandem mass spectrometry

2002 • 52 citations

CORTICOSTEROIDS AND INTERFERONS INHIBIT CYTOKINE-INDUCED PRODUCTION OF IL-8 BY HUMAN ENDOTHELIAL CELLS

2000 • 49 citations

Hepatocyte growth factor is predominantly expressed by the carcinoma cells in non–small-cell lung cancer

2001 • 49 citations

Human growth factor (huGRO), interleukin-8 (IL-8) and interferon-γ-inducible protein (γ-IP-10) gene expression in cultured normal human keratinocytes

1994 • 34 citations

Regulatory roles of IL-17 and IL-17F in G-CSF production by lung microvascular endothelial cells stimulated with IL-1β and/or TNF-α

2004 • 33 citations

IL-17 and IL-17F modulate GM-CSF production by lung microvascular endothelial cells stimulated with IL-1β and/or TNF-α

2004 • 29 citations

Interleukin-17 [IL-17, IL-25]

2003 • 6 citations

Response: Variability Among Human Umbilical Vein Endothelial Cultures

1995 • 3 citations