Hepatocyte growth factor is predominantly expressed by the carcinoma cells in non–small-cell lung cancer

AJCC Cancer Staging Manual

2016 • 16,972 citations

AJCC Cancer Staging Manual

2002 • 6,356 citations

Molecular cloning and expression of human hepatocyte growth factor

1989 • 2,191 citations

Scatter factor is a fibroblast-derived modulator of epithelial cell mobility

1987 • 1,333 citations

Evidence for the identity of human scatter factor and human hepatocyte growth factor.

1991 • 651 citations

Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors

1991 • 491 citations

Expression of the Met/HGF receptor in normal and neoplastic human tissues.

1991 • 481 citations

Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor

1997 • 444 citations

Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement.

1989 • 411 citations

Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction.

1994 • 279 citations

Hepatocyte growth factor/scatter factor—Met signaling in tumorigenicity and invasion/metastasis

1996 • 277 citations

c-Met autocrine activation induces development of malignant melanoma and acquisition of the metastatic phenotype.

1998 • 272 citations

Hepatocyte growth factor inhibits growth of hepatocellular carcinoma cells.

1992 • 256 citations

Hepatocyte growth factor/hepatopoietin A stimulates the growth of rat kidney proximal tubule epithelial cells (RPTE), rat nonparenchymal liver cells, human melanoma cells, mouse keratinocytes and stimulates anchorage-independent growth of SV-40 transformed RPTE

1991 • 253 citations

Hepatocyte growth factor stimulates extensive development of branching duct-like structures by cloned mammary gland epithelial cells

1995 • 231 citations

Identification of a Competitive HGF Antagonist Encoded by an Alternative Transcript

1991 • 224 citations

Marked stimulation of growth and motility of human keratinocytes by hepatocyte growth factor

1991 • 217 citations

Hepatocyte growth factor has potent anti‐proliferative activity in various tumor cell lines

1991 • 207 citations

Overexpression and activation of hepatocyte growth factor/scatter factor in human non-small-cell lung carcinomas

1996 • 193 citations

Expression of c‐met/HGF Receptor in Human Non‐small Cell Lung Carcinomas in vitro and in vivo and Its Prognostic Significance

1996 • 193 citations

Association of immunoreactive hepatocyte growth factor with poor survival in resectable non-small cell lung cancer.

1997 • 167 citations

Evidence for the identy of human scatter factor and human hepatocyte growth factor.

1991 • 163 citations

Hepatocyte growth factor/scatter factor overexpression induces growth, abnormal development, and tumor formation in transgenic mouse livers.

1996 • 150 citations

Heparin induces dimerization and confers proliferative activity onto the hepatocyte growth factor antagonists NK1 and NK2.

1996 • 143 citations

Overexpression of c-met proto-oncogene but not epidermal growth factor receptor or c-erbB-2 in primary human colorectal carcinomas.

1992 • 141 citations

Hepatocyte Growth Factor (HGF)/NK1 Is a Naturally Occurring HGF/Scatter Factor Variant with Partial Agonist/Antagonist Activity

1996 • 137 citations

Hepatocyte growth factor is a growth factor for rat alveolar type II cells.

1994 • 136 citations

Smooth muscle releases an epithelial cell scatter factor which binds to heparin

1989 • 136 citations

Hepatocyte growth factor and Met receptor expression in human pancreatic carcinogenesis.

1995 • 136 citations

Scatter factor/hepatocyte growth factor gene transfer enhances glioma growth and angiogenesis in vivo.

1997 • 122 citations

Role of morphogenetic factors in metastasis of mammary carcinoma cells

1998 • 122 citations

Differential expression of Met/hepatocyte growth factor receptor in subtypes of non-small cell lung cancers

1998 • 114 citations

Hepatocyte growth factor induces proliferation and morphogenesis in nonparenchymal epithelial liver cells

1993 • 113 citations

An alternatively processed mRNA generated from human hepatocyte growth factor gene

1991 • 111 citations

Hepatocyte growth factor/scatter factor is an autocrine factor for human normal bronchial epithelial and lung carcinoma cells.

1993 • 111 citations

The roles of hepatocyte growth factor/scatter factor and met receptor in human cancers (Review).

1998 • 100 citations

Hepatocyte Growth Factor and c-Met/Hepatocyte Growth Factor Receptor in Pulmonary Adenocarcinomas: An Evaluation of Their Expression as Prognostic Markers

1996 • 98 citations

Generation and characterization of a competitive antagonist of human hepatocyte growth factor, HGF/NK1

1993 • 92 citations

Scatter factor stimulates tumor growth and tumor angiogenesis in human breast cancers in the mammary fat pads of nude mice.

1997 • 90 citations

IMMUNOREACTIVITY FOR HEPATOCYTE GROWTH FACTOR/SCATTER FACTOR AND ITS RECEPTOR, met, IN HUMAN LUNG CARCINOMAS AND MALIGNANT MESOTHELIOMAS

1996 • 78 citations

Stimulatory effects of hepatocyte growth factor on normal and neoplastic human bronchial epithelial cells

1995 • 78 citations

Immunohistochemical Detection of Hepatocyte Growth Factor/Scatter Factor in Human Cancerous and Inflammatory Lesions of Various Organs

1993 • 71 citations

Hepatocyte growth factor/scatter factor expression in human mammary epithelium.

1994 • 70 citations

NK1, a Natural Splice Variant of Hepatocyte Growth Factor/Scatter Factor, Is a Partial Agonist In Vivo

1998 • 58 citations

Hepatocyte growth factor in lung morphogenesis and tumor invasion: role as a mediator in epithelium-mesenchyme and tumor-stroma interactions

1996 • 57 citations

Activation of Hepatocyte Growth Factor-Met Autocrine Loop Enhances Tumorigenicity in a Human Lung Adenocarcinoma Cell Line

2000 • 57 citations

In vitro and in vivo expressions of transforming growth factor-alpha and tyrosine kinase receptors in human non-small-cell lung carcinomas.

1993 • 38 citations

Paracrine effects of hepatocyte growth factor/scatter factor on non-small-cell lung carcinoma cell lines

1998 • 34 citations

Autocrine stimulation of motility in SBC-5 human lung carcinoma cells by a two-kringle variant of HGF

1994 • 25 citations