Porcine polymorphonuclear leukocytes generate extracellular microbicidal activity by elastase-mediated activation of secreted proprotegrins

Defensins. Natural peptide antibiotics of human neutrophils.

1985 • 1,411 citations

Cathelicidins: a novel protein family with a common proregion and a variable C‐terminal antimicrobial domain

1995 • 714 citations

Ultrasensitive assays for endogenous antimicrobial polypeptides

1991 • 673 citations

Protegrins: leukocyte antimicrobial peptides that combine features of corticostatic defensins and tachyplesins

1993 • 497 citations

Cell surface-bound elastase and cathepsin G on human neutrophils: a novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteinases.

1995 • 382 citations

hCAP‐18, a cathelin/pro‐bactenecin‐like protein of human neutrophil specific granules

1995 • 339 citations

Defensins and other endogenous peptide antibiotics of vertebrates

1995 • 323 citations

Purification, composition, and activity of two bactenecins, antibacterial peptides of bovine neutrophils

1989 • 295 citations

Neutrophils degrade subendothelial matrices in the presence of alpha-1-proteinase inhibitor. Cooperative use of lysosomal proteinases and oxygen metabolites.

1984 • 253 citations

Extracellular release of antimicrobial defensins by human polymorphonuclear leukocytes

1987 • 238 citations

The potent anti-Staphylococcus aureus activity of a sterile rabbit inflammatory fluid is due to a 14-kD phospholipase A2.

1996 • 208 citations

Posttranslational processing of defensins in immature human myeloid cells

1992 • 180 citations

Antibiotic proteins of polymorphonuclear leukocytes

1996 • 168 citations

Proteolytic cleavage by neutrophil elastase converts inactive storage proforms to antibacterial bactenecins

1992 • 155 citations

Primary structure of a new cysteine proteinase inhibitor from pig leucocytes

1989 • 152 citations

Bactenecins, defense polypeptides of bovine neutrophils, are generated from precursor molecules stored in the large granules.

1990 • 145 citations

Intramolecular inhibition of human defensin HNP-1 by its propiece.

1996 • 128 citations

Proteolytic inactivation of alpha 1-proteinase inhibitor and alpha 1-antichymotrypsin by oxidatively activated human neutrophil metalloproteinases.

1992 • 114 citations

Identification of a new member of the protegrin family by cDNA cloning

1994 • 103 citations

Stimulus-induced maturation of probactenecins, precursors of neutrophil antimicrobial polypeptides.

1991 • 95 citations

The structure of porcine protegrin genes

1995 • 90 citations

Characterization of defensin precursors in mature human neutrophils

1992 • 84 citations

Antibacterial 15-kDa protein isoforms (p15s) are members of a novel family of leukocyte proteins.

1993 • 82 citations

Extracellular accumulation of potently microbicidal bactericidal/permeability-increasing protein and p15s in an evolving sterile rabbit peritoneal inflammatory exudate.

1995 • 82 citations

Susceptibility of Neisseria gonorrhoeae to protegrins

1996 • 80 citations

Purification and Structural Characterization of Bovine Cathelicidins, Precursors of Antimicrobial Peptides

1996 • 71 citations

A Novel cDNA Sequence Encoding a Pig Leukocyte Antimicrobial Peptide with a Cathelin-like Pro-sequence

1993 • 63 citations

An enzyme immunoassay for human defensins

1991 • 60 citations

Functional Inactivation and Structural Disruption of Human α2-Macroglobulin by Neutrophils and Eosinophils

1989 • 49 citations

Pig leukocyte cysteine proteinase inhibitor (PLCPI), a new member of the stefin family

1993 • 43 citations

Molecular cloning of a novel myeloid granule protein

1995 • 31 citations

Purification and properties of porcine polymorphonuclear cells

1987 • 18 citations

Structural characterization of BPI-modulating 15 kDa proteins from rabbit polymorphonuclear leukocytes: Identification of a novel family of leukocyte proteins

1993 • 8 citations