Purification and Structural Characterization of Bovine Cathelicidins, Precursors of Antimicrobial Peptides

Estimation of globular protein secondary structure from circular dichroism

1981 • 2,139 citations

Determination of the helix and β form of proteins in aqueous solution by circular dichroism

1974 • 2,040 citations

Peptide Antibiotics and Their Role in Innate Immunity

1995 • 1,602 citations

Combining evolutionary information and neural networks to predict protein secondary structure

1994 • 1,471 citations

A new collection method for the evaluation of nasal mucus proteins

1998 • 1,297 citations

A simple ultraviolet spectrophotometric method for the determination of protein.

1956 • 1,266 citations

Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system.

1988 • 1,241 citations

A new approach to protein fold recognition

1992 • 1,239 citations

Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation.

1983 • 938 citations

The cystatins: Protein inhibitors of cysteine proteinases

1991 • 813 citations

Cathelicidins: a novel protein family with a common proregion and a variable C‐terminal antimicrobial domain

1995 • 714 citations

The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases.

1988 • 584 citations

Human CAP18: a novel antimicrobial lipopolysaccharide-binding protein

1995 • 566 citations

FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis.

1995 • 499 citations

A new assay for cathepsin B1 and other thiol proteinases

1972 • 394 citations

hCAP‐18, a cathelin/pro‐bactenecin‐like protein of human neutrophil specific granules

1995 • 339 citations

[15] Cleavage at aspartylprolyl bonds

1977 • 319 citations

Evolution of proteins of the cystatin superfamily

1990 • 297 citations

Amphibian skin: A promising resource for antimicrobial peptides

1995 • 275 citations

Structure and bactericidal activity of an antibiotic dodecapeptide purified from bovine neutrophils.

1988 • 272 citations

Amino acid sequences of two proline-rich bactenecins. Antimicrobial peptides of bovine neutrophils.

1990 • 194 citations

Proteolytic cleavage by neutrophil elastase converts inactive storage proforms to antibacterial bactenecins

1992 • 155 citations

Primary structure of a new cysteine proteinase inhibitor from pig leucocytes

1989 • 152 citations

In vivo significance of kinetic constants of protein proteinase inhibitors

1984 • 150 citations

Bactenecins, defense polypeptides of bovine neutrophils, are generated from precursor molecules stored in the large granules.

1990 • 145 citations

Kinetics of the pH-induced inactivation of human cathepsin L

1993 • 140 citations

The cDNA of the neutrophil antibiotic Bac5 predicts a pro-sequence homologous to a cysteine proteinase inhibitor that is common to other neutrophil antibiotics.

1993 • 130 citations

Defensins in granules of phagocytic and non-phagocytic cells

1995 • 129 citations

Complementary DNA sequence of rabbit CAP18—A unique lipopolysaccharide binding protein

1991 • 126 citations

Structure of the gene for porcine peptide antibiotic PR-39, a cathelin gene family member: comparative mapping of the locus for the human peptide antibiotic FALL-39.

1995 • 123 citations

Chemical synthesis and biological activity of a novel antibacterial peptide deduced from a pig myeloid cDNA

1994 • 111 citations

cDNA sequences of three sheep myeloid cathelicidins

1995 • 105 citations

Identification of a new member of the protegrin family by cDNA cloning

1994 • 103 citations

Molecular cloning and chemical synthesis of a novel antibacterial peptide derived from pig myeloid cells.

1994 • 96 citations

Stimulus-induced maturation of probactenecins, precursors of neutrophil antimicrobial polypeptides.

1991 • 95 citations

PMAP-37, a Novel Antibacterial Peptide from Pig Myeloid Cells. cDNA Cloning, Chemical Synthesis and Activity

1995 • 91 citations

The structure of porcine protegrin genes

1995 • 90 citations

A cDNA Derived from Pig Bone Marrow Cells Predicts a Sequence Identical to the Intestinal Antibacterial Peptide PR-39

1993 • 84 citations

Antibacterial 15-kDa protein isoforms (p15s) are members of a novel family of leukocyte proteins.

1993 • 82 citations

Structures of genes for two cathelin‐associated antimicrobial peptides: prophenin‐2 and PR‐39

1995 • 82 citations

CDNA cloning of the neutrophil bactericidal peptide indolicidin

1992 • 74 citations

Chemotactic and protease‐inhibiting activities of antibiotic peptide precursors

1993 • 70 citations

cDNA sequence analysis of an antibiotic dodecapeptide from neutrophils

1992 • 70 citations

PMAP-37, a Novel Antibacterial Peptide from Pig Myeloid Cells. cDNA Cloning, Chemical Synthesis and Activity

1995 • 65 citations

A Novel cDNA Sequence Encoding a Pig Leukocyte Antimicrobial Peptide with a Cathelin-like Pro-sequence

1993 • 63 citations

Protein Folds: A Distance-Based Approach

1995 • 57 citations

Molecular cloning of Bac7, a proline‐ and arginine‐rich antimicrobial peptide from bovine neutrophils

1994 • 51 citations

Biosynthesis of Defensins and Other Antimicrobial Peptides

2007 • 47 citations

Isolation and Molecular Cloning of a Novel Bone Phosphoprotein Related in Sequence to the Cystatin Family of Thiol Protease Inhibitors

1995 • 45 citations

Pig leukocyte cysteine proteinase inhibitor (PLCPI), a new member of the stefin family

1993 • 43 citations

Molecular cloning of a putative homolog of proline/arginine‐rich antibacterial peptides from porcine bone marrow

1993 • 43 citations

A New Type of Low-Molecular Mass Cysteine Proteinase Inhibitor from Pig Leukocytes

1989 • 39 citations

Isolation and Partial Characterization of the Plasma Membrane of Purified Bovine Neutrophils

1980 • 36 citations

Antimicrobial activity of synthetic bactenecin.

1989 • 7 citations