Proteolytic cleavage by neutrophil elastase converts inactive storage proforms to antibacterial bactenecins

A simple ultraviolet spectrophotometric method for the determination of protein.

1956 • 1,266 citations

Cell-Free Immunity in Insects

1987 • 742 citations

Mapping the extended substrate binding site of cathepsin G and human leukocyte elastase. Studies with peptide substrates related to the alpha 1-protease inhibitor reactive site.

1979 • 602 citations

Antibacterial peptides: Key components needed in immunity

1991 • 570 citations

Proteinase 3. A distinct human polymorphonuclear leukocyte proteinase that produces emphysema in hamsters.

1988 • 436 citations

Antibacterial peptides from pig intestine: isolation of a mammalian cecropin.

1989 • 431 citations

Amino acid sequence of PR‐39

1991 • 343 citations

Insect immunity: isolation from immune blood of the dipteran Phormia terranovae of two insect antibacterial peptides with sequence homology to rabbit lung macrophage bactericidal peptides.

1989 • 325 citations

Characterization of proteinase-3 (PR-3), a neutrophil serine proteinase. Structural and functional properties

1991 • 303 citations

Purification, composition, and activity of two bactenecins, antibacterial peptides of bovine neutrophils

1989 • 295 citations

Down-regulation of a serine protease, myeloblastin, causes growth arrest and differentiation of promyelocytic leukemia cells

1989 • 293 citations

Antibiotic proteins of human polymorphonuclear leukocytes.

1989 • 273 citations

Subcellular localization and heterogeneity of neutral proteases in neutrophilic polymorphonuclear leukocytes.

1975 • 254 citations

Azurocidin and a homologous serine protease from neutrophils. Differential antimicrobial and proteolytic properties.

1990 • 214 citations

Purification of three antibacterial proteins from the culture medium of NIH-Sape-4, an embryonic cell line of Sarcophaga peregrina.

1988 • 214 citations

Rapid membrane permeabilization and inhibition of vital functions of gram-negative bacteria by bactenecins

1990 • 199 citations

Amino acid sequences of two proline-rich bactenecins. Antimicrobial peptides of bovine neutrophils.

1990 • 194 citations

Antimicrobial polypeptides of human neutrophils

1990 • 188 citations

Cloning of cDNA for proteinase 3: a serine protease, antibiotic, and autoantigen from human neutrophils.

1990 • 171 citations

The latent collagenase and gelatinase of human polymorphonuclear neutrophil leucocytes

1980 • 168 citations

Antibiotic proteins of human neutrophils.

1990 • 159 citations

Stepwise Cleavage of the Pro Part of Promelittin by Dipeptidylpeptidase IV

1980 • 157 citations

Antimicrobial polypeptides of human neutrophils

1990 • 152 citations

Isolation and characterization of human defensin cDNA clones.

1988 • 145 citations

Bactenecins, defense polypeptides of bovine neutrophils, are generated from precursor molecules stored in the large granules.

1990 • 145 citations

Acidic precursor revealed in human eosinophil granule major basic protein cDNA.

1988 • 133 citations

Chemical Synthesis and Enzymic Processing of Precursor Forms of Cecropins A and B

1989 • 109 citations

A novel type of cytoplasmic granule in bovine neutrophils.

1983 • 108 citations

Stimulus-induced maturation of probactenecins, precursors of neutrophil antimicrobial polypeptides.

1991 • 95 citations

The structure of the rabbit macrophage defensin genes and their organ-specific expression.

1989 • 92 citations

Characterization of two azurphil granule proteases with active-site homology to neutrophil elastase.

1990 • 89 citations

The cDNA sequence coding for prepro-PGS (prepro-magainins) and aspects of the processing of this prepro-polypeptide.

1988 • 84 citations

Processing of precursors by dipeptidylaminopeptidases: a case of molecular ticketing

1990 • 83 citations

Human neutrophil gelatinase is a component of specific granules.

1989 • 77 citations

Isolation of a complementary DNA clone encoding a precursor to human eosinophil major basic protein.

1988 • 54 citations

Activation of human neutrophil gelatinase by endogenous serine proteinases

1988 • 54 citations

Activation of neutrophil collagenase by cathepsin G

1989 • 44 citations

Antibiotics from within: antibacterials from human and animal sources

1990 • 29 citations

Neutrophil and Eosinophil Granules as Stores of “Defense” Proteins

1991 • 27 citations