Aerosol Insulin Induces Regulatory CD8 γδ T Cells That Prevent Murine Insulin-dependent Diabetes

Regulatory T Cell Clones Induced by Oral Tolerance: Suppression of Autoimmune Encephalomyelitis

1994 • 1,995 citations

Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

1993 • 1,087 citations

Oral Tolerance: Immunologic Mechanisms and Treatment of Animal and Human Organ-Specific Autoimmune Diseases by Oral Administration of Autoantigens

1994 • 895 citations

Insulin-Dependent Diabetes Mellitus as an Autoimmune Disease

1994 • 818 citations

Suppression of diabetes in nonobese diabetic mice by oral administration of porcine insulin.

1991 • 562 citations

The Murine Autoimmune Diabetes Model: NOD and Related Strains

1992 • 498 citations

Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes.

1996 • 428 citations

Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23).

1996 • 415 citations

Regulation of IgE Responses to Inhaled Antigen in Mice by Antigen-Specific γδ T Cells

1994 • 406 citations

Transfer of Autoimmune Diabetes Mellitus with Splenocytes from Nonobese Diabetic (NOD) Mice

1986 • 371 citations

Intraepithelial lymphocytes. Anatomical site, not T cell receptor form, dictates phenotype and function.

1989 • 356 citations

The natural immune response to inhaled soluble protein antigens involves major histocompatibility complex (MHC) class I-restricted CD8+ T cell-mediated but MHC class II-restricted CD4+ T cell-dependent immune deviation resulting in selective suppression of immunoglobulin E production.

1993 • 317 citations

Inhibition of experimental autoimmune encephalomyelitis by inhalation but not oral administration of the encephalitogenic peptide: influence of MHC binding affinity

1993 • 280 citations

Transgenic Expression of Mouse Proinsulin II Prevents Diabetes in Nonobese Diabetic Mice

1997 • 248 citations

Studies on the Chemistry of Anaphylaxis (III). Experiments with Isolated Proteins, Especially those of the Hen's Egg

1911 • 211 citations

Insulin Administered Intranasally as an Insulin-Bile Salt Aerosol: Effectiveness and Reproducibility in Normal and Diabetic Subjects

1983 • 191 citations

The BB rat

1987 • 174 citations

Oral Administration of Human Insulin to NOD Mice Generates CD4+ T Cells that Suppress Adoptive Transfer of Diabetes

1994 • 137 citations

Insulin autoantibodies in the pre-diabetic period: Correlation with islet cell antibodies and development of diabetes

1986 • 124 citations

Crosstalk between alpha/beta T cells and gamma/delta T cells in vivo: activation of alpha/beta T-cell responses after gamma/delta T-cell modulation with the monoclonal antibody GL3.

1993 • 118 citations

On the appearance of islet associated autoimmunity in offspring of diabetic mothers: a prospective study from birth

1993 • 117 citations

Similar peptides from two beta cell autoantigens, proinsulin and glutamic acid decarboxylase, stimulate T cells of individuals at risk for insulin-dependent diabetes.

1995 • 103 citations

Islet cell antigens in insulin-dependent diabetes: Pandora's box revisited

1992 • 97 citations

Similar Peptides from Two β Cell Autoantigens, Proinsulin and Glutamic Acid Decarboxylase, Stimulate T Cells of Individuals at Risk for Insulin-Dependent Diabetes

1995 • 86 citations

Suppression of the Immune Response by Nasal Immunization

1994 • 84 citations

Studies on the Chemistry of Anaphylaxis

1908 • 77 citations

Suppression of IgE responses following inhalation of antigen

1987 • 75 citations

Function and specificity of human gamma/delta-positive T cells.

1992 • 69 citations

Islet-reactive T cells are a marker of preclinical insulin-dependent diabetes.

1992 • 67 citations

Suppressive effects of insulin and insulin-like growth factor-1 (IGF1) on immune responses.

1986 • 62 citations

Adoptive transfer of unresponsiveness to allogeneic skin grafts with hepatic gamma delta + T cells.

1994 • 62 citations

An age‐related γδ T cell suppressor activity correlates with the outcome of autoimmunity in experimental Trypanosoma cruzi infection

1993 • 53 citations

Radioassay Determination of Insulin Autoantibodies in NOD Mice: Correlation With Increased Risk of Progression to Overt Diabetes

1989 • 52 citations

Antigen-specific immunotherapy: is it a real possibility to combat T-cell-mediated autoimmunity?

1994 • 48 citations

Suppression of cytotoxic T lymphocyte activity by ?/? T cells in tumor-bearing mice

1995 • 30 citations

Antigen‐specific immunotherapy: Oral tolerance and subcutaneous immunization in the treatment of insulin‐dependent diabetes

1993 • 30 citations

The Temporal Association Between γδ T Cells and the Natural History of Insulin-Dependent Diabetes

1993 • 21 citations

The immunologic insult in type 1 diabetes

1993 • 16 citations

Age-related changes in Tγδ cells of NOD mice

1995 • 16 citations

Type I diabetes in NOD mice is not associated with insulin-specific, autoreactive T cells

1989 • 14 citations

Approaches toward peptide-based immunotherapy of autoimmune diseases

1992 • 11 citations

Expansion of Circulating γδ T Cells in Active Sarcoidosis Closely Correlates with Defects in Cellular Immunity

1995 • 8 citations

Antigen-Specific Therapy for Autoimmune Disease: Prospects for the Prevention of Insulin-Dependent Diabetes

1995 • 7 citations