Mouse apolipoprotein J: characterization of a gene implicated in atherosclerosis.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

1988 • 4,669 citations

PLASMA-HIGH-DENSITY-LIPOPROTEIN CONCENTRATION AND DEVELOPMENT OF ISCHÆMIC HEART-DISEASE

1975 • 2,653 citations

Spontaneous Hypercholesterolemia and Arterial Lesions in Mice Lacking Apolipoprotein E

1992 • 2,189 citations

Glycosaminoglycans: molecular properties, protein interactions, and role in physiological processes

1991 • 1,088 citations

Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI

1991 • 990 citations

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells.

1992 • 897 citations

The sequence 5′-AAUAAA-3′ forms part of the recognition site for polyadenylation of late SV40 mRNAs

1981 • 819 citations

Associations of high-density lipoprotein subclasses and apolipoproteins with ischemic heart disease and coronary atherosclerosis

1987 • 477 citations

Induction of the TRPM-2 gene in cells undergoing programmed death.

1989 • 466 citations

Molecular structure and functional characterization of a human complement cytolysis inhibitor found in blood and seminal plasma: identity to sulfated glycoprotein 2, a constituent of rat testis fluid.

1989 • 412 citations

Atherosclerosis in Transgenic Mice Overexpressing Apolipoprotein A-II

1993 • 355 citations

Clusterin: the intriguing guises of a widely expressed glycoprotein

1992 • 353 citations

Complement proteins C5b-9 induce vesiculation of the endothelial plasma membrane and expose catalytic surface for assembly of the prothrombinase enzyme complex.

1990 • 342 citations

Apolipoprotein J: structure and tissue distribution

1990 • 339 citations

Biosynthesis and molecular cloning of sulfated glycoprotein 2 secreted by rat Sertoli cells

1987 • 336 citations

Dynamics of gene expression for a hippocampal glycoprotein elevated in Alzheimer's disease and in response to experimental lesions in rat

1990 • 334 citations

The apolipoprotein multigene family: biosynthesis, structure, structure-function relationships, and evolution.

1988 • 315 citations

Reduced high density lipoprotein cholesterol in human cholesteryl ester transfer protein transgenic mice

1991 • 300 citations

Secondary structures of proteins and peptides in amphiphilic environments. (A review).

1983 • 299 citations

Synthetic low and high fat diets for the study of atherosclerosis in the mouse.

1990 • 291 citations

Ath-1, a gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice.

1987 • 286 citations

Clusterin (complement lysis inhibitor) forms a high density lipoprotein complex with apolipoprotein A-I in human plasma

1991 • 260 citations

A 70-kDa apolipoprotein designated ApoJ is a marker for subclasses of human plasma high density lipoproteins.

1990 • 260 citations

Changes in brain gene expression shared by scrapie and Alzheimer disease.

1989 • 253 citations

Molecular cloning and characterization of the novel, human complement-associated protein, SP-40,40: a link between the complement and reproductive systems.

1989 • 243 citations

Deposition of the terminal C5b-9 complement complex in infarcted areas of human myocardium.

1986 • 240 citations

Genetic factors affecting blood lipoproteins: the candidate gene approach.

1988 • 225 citations

Apolipoprotein J expression at fluid-tissue interfaces: potential role in barrier cytoprotection.

1993 • 200 citations

Genomic organization and expression of the rat TRPM-2 (clusterin) gene, a gene implicated in apoptosis.

1993 • 194 citations

Identification of an androgen-repressed mRNA in rat ventral prostate as coding for sulphated glycoprotein 2 by cDNA cloning and sequence analysis

1989 • 183 citations

Immunohistochemical localization of the terminal C5b-9 complement complex in human aortic fibrous plaque

1985 • 183 citations

Diet-Induced Hypercholesterolemia in Mice: Prevention by Overexpression of LDL Receptors

1990 • 179 citations

Body Cholesterol Removal: Role of Plasma High-Density Lipoproteins1 1Supported by National Health Service Grants HL 18673, HL 07291, and HL 22682, and a Grant-In-Aid from the American Heart Association (316–3070–2286).

1980 • 156 citations

Immunohistochemical localization of C5b-9, S-protein, C3d and apolipoprotein B in human arterial tissues with atherosclerosis

1987 • 116 citations

Complement receptors and regulatory proteins in human atherosclerotic lesions.

1989 • 110 citations

The complement system in atherosclerosis

1988 • 93 citations

Gene expression in response to acute unilateral ureteral obstruction

1989 • 86 citations

Apolipoprotein J: a membrane policeman?

1992 • 86 citations

Coordinate developmental regulation of purine catabolic enzyme expression in gastrointestinal and postimplantation reproductive tracts.

1991 • 84 citations

Structural analysis of sulphated glycoprotein 2 from amino acid sequence. Relationship to clusterin and serum protein 40,40

1990 • 81 citations

SP‐40,40, a protein involved in the control of the complement pathway, possesses a unique array of disulphide bridges

1992 • 76 citations

Inhibition of the Lytic Action of Cell-bound Terminal Complement Components by Human High Density Lipoproteins and Apoproteins

1983 • 73 citations

Ath-2, a second gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice.

1989 • 71 citations

Platelet activation releases megakaryocyte-synthesized apolipoprotein J, a highly abundant protein in atheromatous lesions.

1993 • 68 citations

Molecular cloning of gp 80, a glycoprotein complex secreted by kidney cells in vitro and in vivo. A link to the reproductive system and to the complement cascade

1991 • 66 citations

ATH-3, a new gene for atherosclerosis in the mouse.

1989 • 53 citations

Human megakaryocytes express clusterin and package it without apolipoprotein A-1 into alpha-granules

1993 • 46 citations

Structure and stability of apolipoprotein J-containing high-density lipoproteins

1992 • 38 citations

Chromosomal assignment of the human homologue encoding SGP-2

1990 • 27 citations

Assignment of pancreatic ribonuclease gene to mouse chromosome 14

1986 • 21 citations

Molecular cloning, characterization, and genetic mapping of an endogenous murine mammary tumor virus proviral unit I of C3H/He mice

1985 • 16 citations

Analysis of Possible Repressor Elements in the 5′-Flanking Region of the Human β-Globin Gene

1989 • 5 citations