Analysis of Possible Repressor Elements in the 5′-Flanking Region of the Human β-Globin Gene

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Position-independent, high-level expression of the human β-globin gene in transgenic mice

1987 • 1,955 citations

A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes

1986 • 1,150 citations

Erythroid-specific expression of human beta-globin genes in transgenic mice.

1985 • 436 citations

The Molecular Genetics of Human Hemoglobin

1984 • 420 citations

The human beta-globin gene 3' enhancer contains multiple binding sites for an erythroid-specific protein.

1988 • 362 citations

THE MOLECULAR GENETICS OF HUMAN HEMOGLOBINS

1980 • 306 citations

The β-globin dominant control region activates homologous and heterologous promoters in a tissue-specific manner

1989 • 302 citations

An erythroid-specific, developmental-stage-independent enhancer far upstream of the human "beta-like globin" genes.

1989 • 280 citations

Regulated expression of human Aγ-, β-, and hybrid γβ-globin genes in transgenic mice: Manipulation of the developmental expression patterns

1986 • 275 citations

A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice.

1989 • 269 citations

Developmental regulation of a cloned adult β-globin gene in transgenic mice

1985 • 215 citations

An embryonic pattern of expression of a human fetal globin gene in transgenic mice

1986 • 204 citations

Two 3' sequences direct adult erythroid-specific expression of human beta-globin genes in transgenic mice.

1987 • 202 citations

An enhancer element lies 3′ to the human A gamma globin gene.

1987 • 135 citations

A 3' enhancer contributes to the stage-specific expression of the human beta-globin gene.

1987 • 128 citations

Detection of Two Tissue-Specific DNA-Binding Proteins with Affinity for Sites in the Mouse β-Globin Intervening Sequence 2

1988 • 66 citations

A protein factor binding to an octamer motif in the γ-globin promoter disappears upon induction of differentiation and hemoglobin synthesis in K562 cells

1987 • 56 citations

Differential expression of human globin genes introduced in K562 cells.

1985 • 47 citations

Mutations in two regions upstream of the^Aγ globin gene canonical promoter affect gene expression

1989 • 39 citations

Detection of two tissue-specific DNA-binding proteins with affinity for sites in the mouse beta-globin intervening sequence 2.

1988 • 24 citations

Purification and characterization of an erythroid cell-specific factor that binds the murine alpha- and beta-globin genes.

1989 • 17 citations