Myosin VIIA is required for aminoglycoside accumulation in cochlear hair cells.

Ionic channels of excitable membranes

1985 • 7,199 citations

ENDOCYTOSIS AND MOLECULAR SORTING

1996 • 1,537 citations

Defective myosin VIIA gene responsible for Usher syndrome type IB

1995 • 1,051 citations

A type VII myosin encoded by the mouse deafness gene shaker-1

1995 • 674 citations

Unconventional Myosins in Inner-Ear Sensory Epithelia

1997 • 531 citations

The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells

1995 • 507 citations

Actin microfilaments play a critical role in endocytosis at the apical but not the basolateral surface of polarized epithelial cells.

1993 • 438 citations

Expression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type 1B.

1995 • 425 citations

Unconventional Myosins

1995 • 362 citations

Autoradiography of gentamicin uptake by the rat proximal tubule cell

1979 • 307 citations

Actin filaments in sensory hairs of inner ear receptor cells.

1977 • 296 citations

The emergence of clathrin-independent pinocytic pathways

1995 • 282 citations

Role of Type I Myosins in Receptor-Mediated Endocytosis in Yeast

1996 • 263 citations

Mechano-electrical transducer currents in hair cells of the cultured neonatal mouse cochlea

1992 • 258 citations

Blockage of the transduction channels of hair cells in the bullfrog's sacculus by aminoglycoside antibiotics

1989 • 257 citations

Aminoglycoside nephrotoxicity

1980 • 245 citations

Outer hair cell loss and supporting cell expansion following chronic gentamicin treatment

1985 • 222 citations

A quantitative comparison of mechanoelectrical transduction in vestibular and auditory hair cells of neonatal mice

1997 • 218 citations

Porcine myosin-VI: characterization of a new mammalian unconventional myosin.

1994 • 218 citations

The transduction channel of hair cells from the bull‐frog characterized by noise analysis.

1986 • 215 citations

Dictyostelium myosin I double mutants exhibit conditional defects in pinocytosis.

1995 • 198 citations

Dictyostelium mutants lacking multiple classic myosin I isoforms reveal combinations of shared and distinct functions.

1996 • 176 citations

Human myosin VIIA responsible for the Usher 1B syndrome: a predicted membrane-associated motor protein expressed in developing sensory epithelia.

1996 • 170 citations

Structural features of the lateral walls in mammalian cochlear outer hair cells

1991 • 157 citations

Human Usher 1B/mouse shaker-1: the retinal phenotype discrepancy explained by the presence/absence of myosin VIIA in the photoreceptor cells

1996 • 153 citations

Two modes of hair cell loss from the vestibular sensory epithelia of the guinea pig inner ear

1995 • 153 citations

Identification of a 120 kd hair-bundle myosin located near stereociliary tips

1993 • 147 citations

Rapid endocytosis of interleukin 2 receptors when clathrin-coated pit endocytosis is inhibited

1994 • 144 citations

Molecular Cloning and Domain Structure of Human Myosin-VIIa, the Gene Product Defective in Usher Syndrome 1B

1996 • 138 citations

Inhibition of apical but not basolateral endocytosis of ricin and folate in Caco-2 cells by cytochalasin D

1994 • 130 citations

Effects of shaker-1 mutations on myosin-VIIa protein and mRNA expression

1997 • 121 citations

Endocytosis of aminoglycoside antibiotics in sensory hair cells

1995 • 117 citations

The morphology and physiology of hair cells in organotypic cultures of the mouse cochlea

1987 • 116 citations

Cochlear cultures as a model system for studying aminoglycoside induced ototoxicity

1991 • 114 citations

Mutation analysis of the mouse myosin VIIA deafness gene

1997 • 113 citations

Genomic Sequence Information Should Be Released Immediately and Freely in the Public Domain

1996 • 111 citations

The preendosomal compartment comprises distinct coated and noncoated endocytic vesicle populations.

1991 • 97 citations

Endocytosis without clathrin

1994 • 90 citations

Suppression and restoration of the microphonic output from the lateral line organ after local application of streptomycin

1964 • 85 citations

Tubulin and microtubules in cochlear hair cells: Comparative immunocytochemistry and ultrastructure

1989 • 80 citations

Ultrastructural localization of gentamicin in the cochlea

1990 • 76 citations

Ototoxicity in vitro: effects of neomycin, gentamicin, dihydrostreptomycin, amikacin, spectinomycin, neamine, spermine and poly-l-lysine

1994 • 72 citations

The effects of cytochalasin D and phorbol myristate acetate on the apical endocytosis of ricin in polarised Caco-2 cells

1996 • 71 citations

Calmodulin controls adaptation of mechanoelectrical transduction by hair cells of the bullfrog's sacculus.

1996 • 66 citations

Subcellular distribution of gentamicin in proximal tubular cells, determined by immunogold labeling

1991 • 65 citations

Adenine nucleoside diphosphates block adaptation of mechanoelectrical transduction in hair cells.

1993 • 65 citations

Freeze fracture analysis of apical membranes in cochlear cultures: differences between basal and apicalcoil outer hair cells and effects of neomycin

1993 • 60 citations

Cellular and subcellular localization of tritiated gentamicin in the guinea pig cochlea following combined treatment with ethacrynic acid

1992 • 59 citations

Unconventional myosins: new frontiers in actin-based motors

1997 • 56 citations

Phosphate Analogs Block Adaptation in Hair Cells by Inhibiting Adaptation-Motor Force Production

1996 • 55 citations

Brush border myosin-I truncated in the motor domain impairs the distribution and the function of endocytic compartments in an hepatoma cell line.

1996 • 46 citations

Stereocilia bundle stiffness: Effects of neomycin sulphate, A23187 and Concanavalin A

1990 • 43 citations

Molecular cloning of a myosin I beta isozyme that may mediate adaptation by hair cells of the bullfrog's internal ear.

1994 • 40 citations

Dual action of ototoxic antibiotics on sensory hair cells

1980 • 39 citations

Structural basis for mechanical transduction in the frog vestibular sensory apparatus: II. The role of microtubules in the organization of the cuticular plate

1994 • 32 citations

Characteristics of gentamicin uptake in the isolated crista ampullaris of the inner EAR of the guinea pig

1987 • 26 citations

Rapid endocytosis of interleukin 2 receptors when clathrin‐coated pit endocytosis is inhibited

1995 • 22 citations

[Ototoxicity of kanamycin studied day by day. Experimental electron microscopic study].

1974 • 12 citations

Ototoxicité de la Kanamycine au jour le jour. Etude expérimentale en microscopie électronique

1974 • 10 citations