Identification of a 120 kd hair-bundle myosin located near stereociliary tips

Thomas, Springfield, Illinois

1965 • 2,935 citations

How the ear's works work

1989 • 852 citations

Cross-links between stereocilia in the guinea pig organ of Corti, and their possible relation to sensory transduction

1984 • 694 citations

Autoradiography using storage phosphor technology

1990 • 531 citations

Tip-link integrity and mechanical transduction in vertebrate hair cells

1991 • 495 citations

Myosin Structure and Function in Cell Motility

1987 • 479 citations

The Mechanism of Muscle Contractio

1986 • 424 citations

Mechanical relaxation of the hair bundle mediates adaptation in mechanoelectrical transduction by the bullfrog's saccular hair cell.

1987 • 407 citations

Unconventional myosins

1992 • 374 citations

Adaptation of mechanoelectrical transduction in hair cells of the bullfrog's sacculus

1987 • 337 citations

Extracellular current flow and the site of transduction by vertebrate hair cells

1982 • 332 citations

Myosin I is located at the leading edges of locomoting Dictyostelium amoebae

1989 • 323 citations

Binding of myosin I to membrane lipids

1989 • 287 citations

Energetics and mechanism of actomyosin adenosine triphosphatase

1976 • 287 citations

Auditory Biochemistry.

1986 • 285 citations

Actin Filaments, Stereocilia, and Hair Cells: How Cells Count and Measure

1992 • 284 citations

Inhibition of myosin ATPase by vanadate ion.

1979 • 269 citations

Phylogenetic analysis of the myosin superfamily

1993 • 258 citations

An active motor model for adaptation by vertebrate hair cells

1992 • 253 citations

MYOSIN-I

1991 • 252 citations

Voltage dependence of adaptation and active bundle movement in bullfrog saccular hair cells.

1989 • 243 citations

RELATIONSHIPS BETWEEN CHEMICAL AND MECHANICAL EVENTS DURING MUSCULAR CONTRACTION

1986 • 241 citations

Myosins of Nonmuscle Cells

1988 • 240 citations

DIRECTIONAL SENSITIVITY OF INDIVIDUAL VERTEBRATE HAIR CELLS TO CONTROLLED DEFLECTION OF THEIR HAIR BUNDLES*

1981 • 230 citations

Propulsion of organelles isolated from Acanthamoeba along actin filaments by myosin-I

1986 • 227 citations

Cross-links between stereocilia in the guinea pig cochlea

1985 • 213 citations

Calmodulin-binding proteins of the microfilaments present in isolated brush borders and microvilli of intestinal epithelial cells.

1980 • 210 citations

Golgi-derived vesicles from developing epithelial cells bind actin filaments and possess myosin-I as a cytoplasmically oriented peripheral membrane protein.

1993 • 192 citations

Perpetual production of hair cells and maturational changes in hair cell ultrastructure accompany postembryonic growth in an amphibian ear.

1985 • 184 citations

Hair Cells: Transduction, Tuning, and Transmission in the Inner Ear

1988 • 181 citations

[12] Myosin active-site trapping with vanadate ion

1982 • 178 citations

Tissue distribution and subcellular localization of mammalian myosin I.

1992 • 175 citations

Localization of the hair cell's transduction channels at the hair bundle's top by iontophoretic application of a channel blocker

1991 • 172 citations

Molecular evolution of the myosin family: relationships derived from comparisons of amino acid sequences.

1993 • 164 citations

Binding of brush border myosin I to phospholipid vesicles.

1990 • 160 citations

Mechanism of the phosphorylation-dependent regulation of smooth muscle heavy meromyosin.

1985 • 149 citations

Characterization of an integral membrane glycoprotein associated with the microfilaments of pig intestinal microvilli.

1983 • 136 citations

Immunoelectron microscopic and immunofluorescent localization of cytoskeletal and muscle-like contractile proteins in inner ear sensory hair cells

1985 • 124 citations

Plasma membrane association of Acanthamoeba myosin I.

1989 • 120 citations

Regulation of tension on hair-cell transduction channels: displacement and calcium dependence

1989 • 120 citations

Three sets of actin filaments in sensory cells of the inner ear. Identification and functional orientation determined by gel electrophoresis, immunofluorescence and electron microscopy

1981 • 119 citations

Three different actin filament assemblies occur in every hair cell: each contains a specific actin crosslinking protein.

1991 • 116 citations

Sites phosphorylated in myosin light chain in contracting smooth muscle.

1988 • 113 citations

Differential localization of Acanthamoeba myosin I isoforms.

1992 • 110 citations

Displacement-clamp measurement of the forces exerted by gating springs in the hair bundle.

1993 • 109 citations

Chemiluminescence detection of proteins from single cells.

1991 • 108 citations

Identification, characterization and cloning of myr 1, a mammalian myosin-I.

1993 • 107 citations

High-purity isolation of bullfrog hair bundles and subcellular and topological localization of constituent proteins.

1991 • 102 citations

Absence of myosin-like immunoreactivity in stereocilia of cochlear hair cells

1982 • 96 citations

Purification and characterization of a mammalian myosin I.

1992 • 89 citations

"Bundle blot" purification and initial protein characterization of hair cell stereocilia.

1989 • 88 citations

Actin-binding and microtubule-associated proteins in the organ of Corti

1992 • 83 citations

Direct photoaffinity labeling by nucleotides of the apparent catalytic site on the heavy chains of smooth muscle and Acanthamoeba myosins.

1981 • 80 citations

Stereochemical aspects of the interaction of myosin and actomyosin with nucleotides

1980 • 79 citations

Evidence concerning the morphogenesis of saccular receptors in the bullfrog (Rana catesbeiana)

1973 • 78 citations

Suppression of muscle contraction by vanadate. Mechanical and ligand binding studies on glycerol-extracted rabbit fibers.

1985 • 78 citations

Mammalian myosin I alpha, I beta, and I gamma: new widely expressed genes of the myosin I family.

1993 • 73 citations

Calmodulin and calmodulin-binding proteins in hair bundles.

1993 • 68 citations

Ca2+ stimulates the Mg2(+)-ATPase activity of brush border myosin I with three or four calmodulin light chains but inhibits with less than two bound.

1991 • 67 citations

Adenine nucleoside diphosphates block adaptation of mechanoelectrical transduction in hair cells.

1993 • 65 citations

Structural and immunological characterization of the myosin-like 110-kD subunit of the intestinal microvillar 110K-calmodulin complex: evidence for discrete myosin head and calmodulin-binding domains.

1988 • 64 citations

Is myosin in the cochlea a basis for active motility?

1980 • 56 citations

Monoclonal antibodies demonstrate limited structural homology between myosin isozymes from Acanthamoeba.

1984 • 54 citations

Special Topic: Molecular Mechanism of Muscle Contraction

1987 • 53 citations

UV-induced vanadate-dependent modification and cleavage of skeletal myosin subfragment 1 heavy chain. 1. Evidence for active site modification

1988 • 48 citations

2-[(4-Azido-2-nitrophenyl)amino]ethyl triphosphate, a novel chromophoric and photoaffinity analog of ATP. Synthesis, characterization, and interaction with myosin subfragment 1

1985 • 42 citations

Studies on insect spermatogenesis. VI. Notes on the formation of the sperm in Coleoptera and Aptera, with a general discussion of flagellate sperms

1924 • 41 citations

Mechanics of glycerinated muscle fibers using nonnucleoside triphosphate substrates

1991 • 41 citations

UV-induced vanadate-dependent modification and cleavage of skeletal myosin subfragment 1 heavy chain. 2. Oxidation of serine in the 23-kDa amino-terminal tryptic peptide

1988 • 36 citations

Transient-kinetic studies of the adenosine triphosphatase activity of scallop heavy meromyosin

1988 • 32 citations

Immunocytochemical localization of myosin, tropomyosin and actin in vestibular hair cells of human fetuses and cats

1989 • 29 citations

Direct photoaffinity labeling of gizzard myosin with [3H]uridine diphosphate places Glu185 of the heavy chain at the active site.

1990 • 18 citations

Purification and characterization of a mammalian myosin I

1992 • 9 citations

Special Topic: Molecular Mechanism Of Muscle Contraction: General Introduction

1987 • 1 citations

Purification of Monoclonal Antibodies

2024 • 1 citations