Discordant Activation of Stress-activated Protein Kinases or c-Jun NH2-terminal Protein Kinases in Tissues of Heat-stressed Mice

Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis

1995 • 5,334 citations

The MAPK signaling cascade

1995 • 3,300 citations

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1994 • 3,219 citations

The stress-activated protein kinase subfamily of c-Jun kinases

1994 • 2,616 citations

The Regulation of AP-1 Activity by Mitogen-activated Protein Kinases

1995 • 2,441 citations

The mitogen-activated protein kinase signal transduction pathway

1993 • 2,174 citations

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.

1993 • 1,902 citations

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis

1996 • 1,784 citations

The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway

1995 • 1,653 citations

Dimerization of cell surface receptors in signal transduction

1995 • 1,631 citations

Independent Human MAP-Kinase Signal Transduction Pathways Defined by MEK and MKK Isoforms

1995 • 1,562 citations

Transcription Factor ATF2 Regulation by the JNK Signal Transduction Pathway

1995 • 1,453 citations

Selective interaction of JNK protein kinase isoforms with transcription factors.

1996 • 1,333 citations

Raf-1 activates MAP kinase-kinase

1992 • 1,308 citations

Heat-Related Deaths during the July 1995 Heat Wave in Chicago

1996 • 1,293 citations

Protein kinase Cα activates RAF-1 by direct phosphorylation

1993 • 1,282 citations

Activation of Mitogen-activated Protein Kinase by H2O2

1996 • 1,202 citations

Parallel signal processing among mammalian MAPKs

1995 • 1,015 citations

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

1994 • 978 citations

ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK

1992 • 948 citations

Identification of a Dual Specificity Kinase That Activates the Jun Kinases and p38-Mpk2

1995 • 775 citations

Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases

1992 • 714 citations

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation.

1994 • 639 citations

Raf meets Ras: completing the framework of a signal transduction pathway

1994 • 591 citations

Signal transduction by tumor necrosis factor mediated by JNK protein kinases.

1994 • 456 citations

Animal cell culture; a practical approach

1993 • 432 citations

Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity.

1990 • 396 citations

Effect of a dominant inhibitory Ha-ras mutation on neuronal differentiation of PC12 cells.

1990 • 327 citations

Role of Mitogen-activated Protein Kinase Phosphatase during the Cellular Response to Genotoxic Stress

1995 • 284 citations

The stress-activated protein kinases are major c-Jun amino-terminal kinases activated by ischemia and reperfusion

1994 • 266 citations

Mechanical stretch activates the stress‐activated protein kinase in cardiac myocytes

1996 • 247 citations

Inhibition of Ras-Induced DNA Synthesis by Expression of the Phosphatase MKP-1

1994 • 214 citations

Stress-Activated Protein Kinases in Cardiovascular Disease

1996 • 204 citations

Acute hypertension activates mitogen-activated protein kinases in arterial wall.

1996 • 200 citations

Discordant expression of heat shock protein mRNAs in tissues of heat-stressed rats.

1990 • 186 citations

Inhibition of G₁ Cyclin-Dependent Kinase Activity during Growth Arrest of Human Breast Carcinoma Cells by Prostaglandin A₂

1996 • 113 citations

Characterization of purified endosomes containing the antidiuretic hormone-sensitive water channel from rat renal papilla.

1994 • 44 citations

Characterization of purified endosomes containing the antidiuretic hormone-sensitive water channel from rat renal papilla.

1994 • 44 citations

Hypothalamic epinephrine is released into hypophysial portal blood during stress

1985 • 43 citations

Vasopressin-induced heat shock protein expression in renal tubular cells.

1996 • 32 citations