Acute hypertension activates mitogen-activated protein kinases in arterial wall.

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1994 • 3,219 citations

The stress-activated protein kinase subfamily of c-Jun kinases

1994 • 2,616 citations

The Regulation of AP-1 Activity by Mitogen-activated Protein Kinases

1995 • 2,441 citations

The mitogen-activated protein kinase signal transduction pathway

1993 • 2,174 citations

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

1987 • 2,107 citations

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1994 • 1,999 citations

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.

1993 • 1,902 citations

Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

1990 • 1,592 citations

Raf-1 activates MAP kinase-kinase

1992 • 1,308 citations

The MAP kinase cascade is essential for diverse signal transduction pathways

1993 • 1,091 citations

Parallel signal processing among mammalian MAPKs

1995 • 1,015 citations

Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter

1992 • 980 citations

Integration of MAP Kinase Signal Transduction Pathways at the Serum Response Element

1995 • 935 citations

Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload.

1988 • 877 citations

Replication of smooth muscle cells in vascular disease.

1986 • 770 citations

Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases

1992 • 714 citations

Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complex.

1990 • 647 citations

Molecular characterization of the stretch-induced adaptation of cultured cardiac cells. An in vitro model of load-induced cardiac hypertrophy.

1992 • 611 citations

Cell proliferation in human coronary arteries.

1990 • 532 citations

Stretching cardiac myocytes stimulates protooncogene expression.

1990 • 470 citations

Alpha- and beta-adrenergic stimulation induces distinct patterns of immediate early gene expression in neonatal rat myocardial cells. fos/jun expression is associated with sarcomere assembly; Egr-1 induction is primarily an alpha 1-mediated response.

1990 • 444 citations

Restenosis after percutaneous transluminal coronary angioplasty: Pathologic observations in 20 patients

1991 • 411 citations

Functional analysis of a growth factor-responsive transcription factor complex

1993 • 386 citations

Heterodimer formation of cJun and ATF-2 is responsible for induction of c-jun by the 243 amino acid adenovirus E1A protein.

1993 • 380 citations

Control of Cardiac Gene Expression by Mechanical Stress

1993 • 343 citations

The regulation of AP-1 activity by mitogen-activated protein kinases

1996 • 312 citations

Angiotensin II Partly Mediates Mechanical Stress–Induced Cardiac Hypertrophy

1995 • 309 citations

Mechanical loading activates mitogen-activated protein kinase and S6 peptide kinase in cultured rat cardiac myocytes

1993 • 290 citations

Role of Mitogen-activated Protein Kinase Phosphatase during the Cellular Response to Genotoxic Stress

1995 • 284 citations

Control of hypertrophic versus hyperplastic growth of vascular smooth muscle cells

1989 • 223 citations

Mechanical stress activates protein kinase cascade of phosphorylation in neonatal rat cardiac myocytes.

1995 • 221 citations

Stress-induced heat shock protein 70 expression in adrenal cortex: an adrenocorticotropic hormone-sensitive, age-dependent response.

1991 • 215 citations

Vascular heat shock protein expression in response to stress. Endocrine and autonomic regulation of this age-dependent response.

1993 • 214 citations

Angiotensin II stimulates the pp44 and pp42 mitogen-activated protein kinases in cultured rat aortic smooth muscle cells

1992 • 210 citations

Regulation of endothelin-1 gene expression by Fos and Jun.

1991 • 149 citations

MAP kinase and the activation of quiescent cells

1993 • 140 citations

Activation of Mitogen-Activated Protein Kinase in Porcine Carotid Arteries

1995 • 135 citations

Angiotensin II stimulates two myelin basic protein/microtubule-associated protein 2 kinases in cultured vascular smooth muscle cells.

1992 • 128 citations

Restenosis after percutaneous transluminal coronary angioplasy

1988 • 119 citations

Acute Hypertension Induces Heat-Shock Protein 70 Gene Expression in Rat Aorta

1995 • 113 citations

Effects of neurohormonal stress and aging on the activation of mammalian heat shock factor 1.

1994 • 105 citations

Autoinduction of Transforming Growth Factor β1 Is Mediated by the AP-1 Complex

1990 • 99 citations

Positive regulation of the skeletal alpha-actin gene by Fos and Jun in cardiac myocytes.

1992 • 86 citations

Cell signalling and the control of gene transcription

1994 • 81 citations

New perspectives in hypertension research. Potentials of vascular biology.

1994 • 81 citations

Comparison of Blood Vessel Wall Dimensions in Normotensive and Hypertensive Rats by Histometric and Morphometric Methods

1983 • 53 citations

Ras Activity Is Required for Phenylephrine-Induced Activation of Mitogen-Activated Protein Kinase in Cardiac Muscle Cells

1994 • 52 citations

Smooth muscle cell proliferation. Expression and kinase activities of p34cdc2 and mitogen-activated protein kinase homologues.

1993 • 45 citations

Control of Cardiac Gene Expression by Mechanical Stress

1993 • 41 citations

Role of the L-arginine-nitric oxide pathway in vascular smooth muscle.

1993 • 28 citations

Behavioural medicine in cardiovascular disorders

1988 • 26 citations

Integration of hypertension research in the era of molecular biology

1995 • 16 citations

Restenosis after Percutaneous Transluminal Coronary Angioplasty

1992 • 4 citations