An N-Ethyl-N-Nitrosourea Mutagenesis Screen for Epigenetic Mutations in the Mouse

Gene Action in the X-chromosome of the Mouse (Mus musculus L.)

1961 • 3,881 citations

Epigenetic Reprogramming in Mammalian Development

2001 • 2,978 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome

1991 • 1,469 citations

Dnmt3L and the Establishment of Maternal Genomic Imprints

2001 • 1,356 citations

The mouse; its reproduction and development

1968 • 1,290 citations

Parental imprinting of the mouse H19 gene

1991 • 1,192 citations

Requirement for Xist in X chromosome inactivation

1996 • 995 citations

Tsix, a gene antisense to Xist at the X-inactivation centre

1999 • 809 citations

Preferential inactivation of the paternally derived X chromosome in the extraembryonic membranes of the mouse

1975 • 783 citations

Genome-wide, large-scale production of mutant mice by ENU mutagenesis

2000 • 681 citations

X-chromosome inactivation: counting, choice and initiation

2001 • 678 citations

Genomic Imprinting Disrupted by a Maternal Effect Mutation in the Dnmt1 Gene

2001 • 675 citations

A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse

2000 • 661 citations

Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome

1991 • 617 citations

Histone macroH2A1 is concentrated in the inactive X chromosome of female mammals

1998 • 591 citations

A Shift from Reversible to Irreversible X Inactivation Is Triggered during ES Cell Differentiation

2000 • 552 citations

Targeted Mutagenesis of Tsix Leads to Nonrandom X Inactivation

1999 • 509 citations

Methylation of Histone H3 at Lys-9 Is an Early Mark on the X Chromosome during X Inactivation

2001 • 504 citations

Synergism of Xist Rna, DNA Methylation, and Histone Hypoacetylation in Maintaining X Chromosome Inactivation

2001 • 482 citations

Mouse ENU Mutagenesis

1999 • 414 citations

Imprinting and the Epigenetic Asymmetry Between Parental Genomes

2001 • 411 citations

Genomic imprinting of p57KIP2, a cyclin–dependent kinase inhibitor, in mouse

1995 • 288 citations

Disruption of Imprinted X Inactivation by Parent-of-Origin Effects at Tsix

2000 • 271 citations

CTCF, a Candidate Trans -Acting Factor for X-Inactivation Choice

2002 • 271 citations

Biallelic expression of imprinted genes in the mouse germ line: implications for erasure, establishment, and mechanisms of genomic imprinting.

1995 • 263 citations

Mammalian X-Chromosome Action: Inactivation Limited in Spread and in Region of Origin

1963 • 247 citations

Maternal imprinting of the mouse Snrpn gene and conserved linkage homology with the human Prader–Willi syndrome region

1992 • 243 citations

Non-random X-chromosome inactivation in mouse X-autosome translocation embryos—location of the inactivation centre

1983 • 208 citations

Mechanisms of genomic imprinting

1999 • 203 citations

Forty years of decoding the silence in X-chromosome inactivation

2001 • 177 citations

A phenotype-based screen for embryonic lethal mutations in the mouse

1998 • 174 citations

Histone H2A variants and the inactive X chromosome: identification of a second macroH2A variant

2001 • 168 citations

Possible Mechanisms of X Chromosome Inactivation

1971 • 133 citations

The evolution of dosage-compensation mechanisms

2000 • 133 citations

Controlling elements in the mouse: IV. Evidence of non-randomX-inactivation

1981 • 113 citations

Imprinting of a RING Zinc-Finger Encoding Gene in the Mouse Chromosome Region Homologous to the Prader-Willi Syndrome Genetic Region

1999 • 110 citations

Mapping the murine Xce locus with (CA)n repeats

1993 • 110 citations

Evidence of non-random X chromosome activity in the mouse

1972 • 98 citations

X chromosome inactivation mosaicism in the mouse

1971 • 92 citations

Imprinted X inactivation in eutherians: a model of gametic execution and zygotic relaxation

2001 • 89 citations

Inactivation System of the Mammalian X Chromosome

1973 • 88 citations

Effect of dose fractionation on the ethylnitrosourea induction of specific-locus mutations in mouse spermatogonia.

1982 • 88 citations

Controlling elements in the mouseX-chromosome: I. Interaction with the X-linked genes

1969 • 79 citations

Analysis of Sequence Upstream of the Endogenous H19 Gene Reveals Elements Both Essential and Dispensable for Imprinting

2002 • 78 citations

X inactivation analysis and DNA methylation studies of the ubiquitin activating enzyme E1 and PCTAIRE-1 genes in human and mouse

1996 • 76 citations

Random Mutagenesis Screen for Dominant Behavioral Mutations in Mice

1997 • 66 citations

Autosomal Dominant Mutations Affecting X Inactivation Choice in the Mouse

2002 • 65 citations

Genetic control over the inactivation of autosomal genes attached to the X-chromosome

1965 • 60 citations

The flat-top gene is required for the expansion and regionalization of the telencephalic primordium

1999 • 58 citations

Methylation profiles of DXPas34 during the onset of X-inactivation

2001 • 55 citations

Controlling elements in the mouse: V. Linkage tests with X-linked genes

1981 • 54 citations

Primary non-random X-inactivation caused by controlling elements in the mouse demonstrated at the cellular level

1982 • 53 citations

Recycling to remodel: evolution of dosage-compensation complexes

2000 • 47 citations

Molecular Cloning of Antisense Transcripts of the MouseXistGene

1999 • 41 citations

Interaction between the Xce locus and imprinting of the paternal X chromosome in mouse yolk-sac endoderm

1983 • 37 citations

Variation forXchromosome expression in mice detected by electrophoresis of phosphoglycerate kinase

1978 • 37 citations

Molecular correlates of the murine Xce locus

1998 • 29 citations

Expression-based assay of an X-linked gene to examine effects of the X-controlling element (Xce) locus

2000 • 28 citations

Evidence for translational regulation of the imprinted Snurf-Snrpn locus in mice

2002 • 23 citations

The Use of Mouse X-Autosome Translocations in the Study of X-Inactivation Pathways and Nonrandomness

1978 • 21 citations

Muta-genetics or muta-genomics: the feasibility of large-scale mutagenesis and phenotyping programs

2000 • 19 citations

The mutagenic activity of ethylnitrosourea at low doses in spermatogonia of the mouse as assessed by the specific-locus test

1998 • 18 citations

Do X Chromosomes Set Boundaries?

2002 • 15 citations