Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood–brain barrier breakdown in vivo

FINE STRUCTURAL LOCALIZATION OF A BLOOD-BRAIN BARRIER TO EXOGENOUS PEROXIDASE

1967 • 2,534 citations

Occludin: a novel integral membrane protein localizing at tight junctions.

1993 • 2,466 citations

Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1)

1987 • 1,712 citations

Astrocytes induce blood–brain barrier properties in endothelial cells

1987 • 1,593 citations

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly.

1992 • 1,330 citations

Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions.

1994 • 949 citations

Tight junctions and the molecular basis for regulation of paracellular permeability

1995 • 825 citations

A cell culture model of the blood-brain barrier.

1991 • 753 citations

Electrical resistance across the blood‐brain barrier in anaesthetized rats: a developmental study.

1990 • 736 citations

A novel endothelial-specific membrane protein is a marker of cell-cell contacts.

1992 • 637 citations

A functional assay for proteins involved in establishing an epithelial occluding barrier: identification of a uvomorulin-like polypeptide.

1986 • 510 citations

Cingulin, a new peripheral component of tight junctions

1988 • 505 citations

Modulation of tight junction structure in blood-brain barrier endothelial cells Effects of tissue culture, second messengers and cocultured astrocytes

1994 • 361 citations

Evidence for dendritic competition in the developing retina

1982 • 345 citations

Polymorphonuclear leukocyte adhesion triggers the disorganization of endothelial cell-to-cell adherens junctions.

1996 • 334 citations

Molecular cloning and expression of murine vascular endothelial- cadherin in early stage development of cardiovascular system

1996 • 325 citations

Development and characterisation of a rat brain capillary endothelial culture: towards an in vitro blood-brain barrier

1992 • 319 citations

Evidence that tyrosine phosphorylation may increase tight junction permeability

1995 • 318 citations

Association of intercellular adhesion molecule-1 (ICAM-1) with actin-containing cytoskeleton and alpha-actinin.

1992 • 309 citations

Cell signalling: MAGUK magic

1996 • 248 citations

Age-related effects of interleukin-1 beta on polymorphonuclear neutrophil-dependent increases in blood-brain barrier permeability in rats

1997 • 244 citations

Intercellular adhesion molecule 1 activation induces tyrosine phosphorylation of the cytoskeleton-associated protein cortactin in brain microvessel endothelial cells.

1994 • 241 citations

A 220-kD undercoat-constitutive protein: its specific localization at cadherin-based cell-cell adhesion sites.

1991 • 234 citations

Leukocyte adhesion to vascular endothelium induces E-selectin linkage to the actin cytoskeleton.

1996 • 212 citations

The molecular organization of tight junctions.

1993 • 201 citations

Cerebrovascular Permeability Coefficients to Sodium, Potassium, and Chloride

1986 • 198 citations

Adhesive ligand binding to integrin alpha IIb beta 3 stimulates tyrosine phosphorylation of novel protein substrates before phosphorylation of pp125FAK

1993 • 192 citations

OVERRIDING THE BRAIN'S INTRINSIC RESISTANCE TO LEUKOCYTE RECRUITMENT WITH INTRAPARENCHYMAL INJECTIONS OF RECOMBINANT CHEMOKINES

1996 • 181 citations

Beta 2 integrin-dependent protein tyrosine phosphorylation and activation of the FGR protein tyrosine kinase in human neutrophils.

1994 • 174 citations

Transcytosis of macromolecules through the blood-brain barrier: a cell biological perspective and critical appraisal

1989 • 173 citations

Blood-Brain Barrier Abnormalities in Longstanding Multiple Sclerosis Lesions. An Immunohistochemical Study

1994 • 162 citations

Permeability of bovine brain microvessel endothelial cells in vitro: Barrier tightening by a factor released from astroglioma cells

1992 • 161 citations

Intracerebral injection of proinflammatory cytokines or leukocyte chemotaxins induces minimal myelomonocytic cell recruitment to the parenchyma of the central nervous system.

1992 • 156 citations

Immunohistochemical localization of adherens junction components in blood-brain barrier microvessels of the rat

1993 • 149 citations

Ultrastructural studies of the blood-retina barrier after exposure to interleukin-1 beta or tumor necrosis factor-alpha.

1994 • 147 citations

Cingulin: Characterization and localization

1989 • 138 citations

Acute experimental allergic encephalomyelitis in the mouse: Immunopathology of the developing lesion

1985 • 134 citations

Electrical resistance and macromolecular permeability of brain endothelial monolayer cultures

1987 • 129 citations

Astrocytes induce neural microvascular endothelial cells to form capillary‐like structures in vitro

1990 • 125 citations

Cell adhesion, cell junctions and the blood—brain barrier

1996 • 110 citations

Phosphorylation of the tight-junction protein ZO-1 in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance

1989 • 108 citations

Cell adhesion molecules on vessels during inflammation in the mouse central nervous system

1994 • 105 citations

Demyelination in the central nervous system following a delayed-type hypersensitivity response to bacillus Calmette-Guérin

1995 • 104 citations

The blood-retinal barrier in experimental autoimmune uveoretinitis. Leukocyte interactions and functional damage.

1994 • 93 citations

Extravasation of polymorphonuclear leukocytes from the cerebral microvasculature

1985 • 70 citations

Adhesion molecule expression on murine cerebral endothelium following the injection of a proinflammagen or during acute neuronal degeneration

1995 • 69 citations

Phosphorylation of the tight junction protein cingulin and the effects of protein kinase inhibitors and activators in MDCK epithelial cells

1995 • 68 citations

Differentiation of Brain Endothelial Cells in Cell Culture

1991 • 67 citations

The tight-junction-specific protein ZO-l is a component of the human and rat blood-brain barriers

1991 • 63 citations

Microvascular and Neuronal Consequences of Common Carotid Artery Thrombosis and Platelet Embolization in Rats

1993 • 48 citations

Immunofluorescent labeling of tight junctions in the rat brain and spinal cord

1992 • 28 citations

Preparation of central nervous system tissue for light and electron microscopy

1992 • 15 citations

Electrolyte Transport

1992 • 13 citations