Properties of Metastasizing and Nonmetastasizing Human Melanoma Cells

Plasminogen Activators, Tissue Degradation, and Cancer

1985 • 2,584 citations

Signal transduction from the extracellular matrix.

1993 • 1,727 citations

Biology and biochemistry of proteinases in tumor invasion

1993 • 1,264 citations

A study of tumor progression: The precursor lesions of superficial spreading and nodular melanoma

1984 • 963 citations

Tumor invasion and the extracellular matrix.

1983 • 960 citations

Integrin distribution in malignant melanoma: association of the beta 3 subunit with tumor progression.

1990 • 771 citations

Tumor invasion through the human amniotic membrane: Requirement for a proteinase cascade

1986 • 764 citations

Elevated levels of the α5β1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells

1990 • 746 citations

Role of integrins and other cell adhesion molecules in tumor progression and metastasis.

1993 • 668 citations

Type IV collagenases in tumor invasion and metastasis

1990 • 502 citations

Enhancement of LFA-1-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes

1989 • 482 citations

Role of the alpha v beta 3 integrin in human melanoma cell invasion.

1992 • 414 citations

Involvement of integrin alpha V gene expression in human melanoma tumorigenicity.

1992 • 380 citations

In Vitro and in Vivo Consequences of VLA-2 Expression on Rhabdomyosarcoma Cells

1991 • 323 citations

Directed Plasminogen Activation at the Surface of Normal and Malignant Cells

1991 • 291 citations

Biology of tumor progression in human melanocytes.

1987 • 236 citations

Characterization of integrin receptors in normal and neoplastic human brain.

1993 • 221 citations

Integrin expression in human melanoma cells with differing invasive and metastatic properties

1992 • 197 citations

Membrane receptors for extracellular matrix macromolecules: relationship to cell adhesion and tumor metastasis

1987 • 184 citations

Phenotypic dynamics of tumor progression in human malignant melanoma

1985 • 172 citations

Establishment and characterization of a human melanoma cell line (MV3) which is highly metastatic in nude mice

1991 • 158 citations

Metastatic behavior of human melanoma cell lines in nude mice correlates with urokinase-type plasminogen activator, its type-1 inhibitor, and urokinase-mediated matrix degradation.

1991 • 156 citations

Plasminogen activators, their inhibitors, and urokinase receptor emerge in late stages of melanocytic tumor progression.

1994 • 150 citations

Signaling by integrins: implications for tumorigenesis.

1993 • 150 citations

The 72 kDa type IV collagenase is modulated via differential expression of alpha v beta 3 and alpha 5 beta 1 integrins during human melanoma cell invasion.

1993 • 147 citations

Adhesion of T and B lymphocytes to extracellular matrix and endothelial cells can be regulated through the beta subunit of VLA

1992 • 139 citations

Antigen expression of metastasizing and non-metastasizing human melanoma cells xenografted into nude mice

1991 • 124 citations

Integrin expression in cutaneous malignant melanoma: Association of the α₃/β₁ heterodimer with tumor progression

1993 • 113 citations

β₁ Integrin‐mediated lymphocyte adherence to extracellular matrix is enhanced by phorbol ester treatment

1991 • 104 citations

Identification of a Melanoma Progression Antigen as Integrin VLA-2

1991 • 89 citations

Origin and biology of cancer metastasis

1989 • 86 citations

Integrin expression in human melanoma cell lines: Heterogeneity of vitronectin receptor composition and function

1991 • 78 citations

Protein and messenger RNA levels of plasminogen activators and inhibitors analyzed in 22 human tumor cell lines.

1990 • 71 citations

Regulation of integrin‐mediated adhesion to laminin and collagen in human melanocytes and in non‐metastatic and highly metastatic human melanoma cells

1993 • 70 citations

Role of the alpha 5 beta 1 integrin receptor in the proliferative response of quiescent human melanoma cells to fibronectin.

1992 • 57 citations

Tumor progression in human malignant melanoma is associated with changes in α6/β1 laminin receptor

1991 • 45 citations

From adhesion to signalling: roles of integrins in the biology of human melanoma.

1993 • 38 citations

Mitogenic activity of fibronectin and laminin on human melanoma is mediated by β1 integrins

1993 • 19 citations

Progression markers in metastasizing human melanoma cells xenografted to nude mice (review).

1989 • 18 citations

The Metastatic Cascade: Potential Approaches for the Inhibition of Metastasis

1988 • 11 citations