Developmental regulation and tissue-specific expression of the human muscle creatine kinase gene.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

Expression of a single transfected cDNA converts fibroblasts to myoblasts

1987 • 3,373 citations

DNA cloning : a practical approach

1985 • 2,302 citations

DNA sequence analysis with a modified bacteriophage T7 DNA polymerase.

1987 • 2,266 citations

Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene

1985 • 1,836 citations

The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection.

1982 • 1,371 citations

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

1985 • 1,248 citations

The ovalbumin gene - sequence of putative control regions

1980 • 996 citations

Promoter Sequences of Eukaryotic Protein-Coding Genes

1980 • 971 citations

Plasticity of the Differentiated State

1985 • 839 citations

[72] Identification of regulatory elements of cloned genes with functional assays

1987 • 477 citations

Upstream regions of the human cardiac actin gene that modulate its transcription in muscle cells: presence of an evolutionarily conserved repeated motif.

1986 • 432 citations

Organization and sequence of the human insulin-like growth factor I gene. Alternative RNA processing produces two insulin-like growth factor I precursor peptides.

1986 • 371 citations

Coordinate regulation of contractile protein synthesis during myoblast differentiation

1978 • 321 citations

Cardiac alpha- and beta-myosin heavy chain genes are organized in tandem.

1984 • 320 citations

Specificity of elevated serum MB creatine phosphokinase activity in the diagnosis of acute myocardial infarction

1975 • 289 citations

The ontogeny of creatine kinase isozymes

1964 • 259 citations

Myogenic lineage determination and differentiation: Evidence for a regulatory gene pathway

1988 • 253 citations

The muscle creatine kinase gene is regulated by multiple upstream elements, including a muscle-specific enhancer.

1988 • 236 citations

Duplicated CArG Box Domains Have Positive and Mutually Dependent Regulatory Roles in Expression of the Human α-Cardiac Actin Gene

1987 • 192 citations

12 Creatine Kinase (Adenosine 5′-Triphosphate-Creatine Phosphotransferase)

1973 • 188 citations

Nucleic Acid Hybridisation — A Practical Approach

1986 • 184 citations

Transcriptional regulation of the muscle creatine kinase gene and regulated expression in transfected mouse myoblasts.

1986 • 173 citations

Coordinate accumulation of contractile protein mRNAs during myoblast differentiation

1979 • 153 citations

Molecular Biology of Muscle Development

1987 • 151 citations

Multiple 5'-flanking regions of the human alpha-skeletal actin gene synergistically modulate muscle-specific expression.

1987 • 150 citations

Delimitation and characterization of cis-acting DNA sequences required for the regulated expression and transcriptional control of the chicken skeletal alpha-actin gene.

1986 • 137 citations

The correlation between the synthesis of skeletal muscle actin, myosin heavy chain, and myosin light chain and the accumulation of corresponding mRNA sequences during myogenesis

1981 • 135 citations

Developmentally regulated expression of chimeric genes containing muscle actin DNA sequences in transfected myogenic cells.

1984 • 123 citations

Expression and regulation of chicken actin genes introduced into mouse myogenic and nonmyogenic cells.

1984 • 114 citations

A Single Troponin T Gene Regulated by Different Programs in Cardiac and Skeletal Muscle Development

1984 • 113 citations

Regulation of muscle gene expression

1982 • 112 citations

Two-level regulation of cardiac actin gene transcription: muscle-specific modulating factors can accumulate before gene activation.

1986 • 108 citations

Transcriptional and cell cycle-mediated regulation of myosin heavy chain gene expression during muscle cell differentiation.

1983 • 99 citations

Transcriptional regulation of nicotinic acetylcholine receptor genes during muscle development.

1986 • 96 citations

A 5′-Flanking Region of the Chicken Acetylcholine Receptor α-Subunit Gene Confers Tissue Specificity and Developmental Control of Expression in Transfected Cells

1987 • 90 citations

Complex regulation of the muscle-specific contractile protein (troponin I) gene.

1987 • 88 citations

Isolation and sequence analysis of a full-length cDNA for human M creatine kinase

1986 • 87 citations

Tissue restricted and stage specific transcription is maintained within 411 nucleotides flanking the 5′ end of the chicken α-skeletal actin gene

1986 • 86 citations

CArG boxes in the human cardiac alpha-actin gene are core binding sites for positive trans-acting regulatory factors.

1987 • 84 citations

Tissue-Specific and Developmentally Regulated Expression of a Chimeric Actin-Globin Gene in Transgenic Mice

1986 • 82 citations

Differentiation of creatine phosphokinase during myogenesis: Quantitative fractionation of isozymes

1977 • 79 citations

Influence of thyroid hormone on the in vitro translational activity of specific mRNAs in the rat heart.

1983 • 78 citations

Differentiation, not determination, regulates muscle gene activation: transfection of troponin I genes into multipotential and muscle lineages of 10T1/2 cells.

1985 • 77 citations

Complete nucleotide sequence of dog heart creatine kinase mRNA: conservation of amino acid sequence within and among species.

1985 • 56 citations

The mouse muscle creatine kinase cDNA and deduced amino acid sequences: Comparison to evolutionarily related enzymes

1985 • 55 citations

Occurrence of Heterogenous Forms of the Subunits of Creatine Kinase in Various Muscle and Nonmuscle Tissues and Their Behaviour during Myogenesis

1981 • 53 citations

Hierarchies of regulatory genes may specify mammalian development

1988 • 50 citations

The primary structure of chicken B-creatine kinase and evidence for heterogeneity of its mRNA

1986 • 49 citations

Expression of a rat brain creatine kinase-β-galactosidase fusion protein in Escherichia coli and derivation of the complete amino acid sequence of rat brain creatine kinase

1985 • 47 citations

The complete nucleotide sequence of canine brain B creatine kinase mRNA: Homology in the coding and 3′ noncoding regions among species

1986 • 43 citations

Isolation of a functional human gene for brain creatine kinase.

1988 • 30 citations

Human creatine kinase-B complementary DNA. Nucleotide sequence, gene expression in lung cancer, and chromosomal assignment to two distinct loci.

1987 • 24 citations

Expression of the rat myosin light-chain 2 gene in transgenic mice: stage specificity, developmental regulation, and interrelation with the endogenous gene.

1988 • 18 citations