Degradation of extracellular matrix proteins by hemorrhagic metalloproteinases

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Laminin–a glycoprotein from basement membranes.

1979 • 2,372 citations

Basement membrane complexes with biological activity

1986 • 1,489 citations

Isolation and characterization of type IV procollagen, laminin, and heparan sulfate proteoglycan from the EHS sarcoma

1982 • 1,225 citations

H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

1988 • 1,050 citations

Tumor invasion and the extracellular matrix.

1983 • 960 citations

Laminin and Other Basement Membrane Components

1987 • 900 citations

BIOCHEMICAL INTERACTIONS OF TUMOR CELLS WITH THE BASEMENT MEMBRANE

1986 • 693 citations

Biochemical and immunological characterization of the secreted forms of human neutrophil gelatinase.

1985 • 625 citations

Normal and abnormal aspects of proteinuria

1986 • 536 citations

A metalloproteinase from human rheumatoid synovial fibroblasts that digests connective tissue matrix components. Purification and characterization.

1986 • 515 citations

Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation, characterization, and substrates.

1985 • 506 citations

Proteolytic degradation of extracellular matrix in tumor invasion

1987 • 484 citations

Biological activities of laminin

1985 • 470 citations

Laminin-nidogen complex. Extraction with chelating agents and structural characterization

1987 • 453 citations

A unique signature identifies a family of zinc‐dependent metallopeptidases

1989 • 453 citations

Comparison of human stromelysin and collagenase by cloning and sequence analysis

1986 • 443 citations

The role of proteinase in cellular invasiveness

1983 • 297 citations

Nidogen: a new, self‐aggregating basement membrane protein

1983 • 275 citations

Hemorrhagic toxins from western diamondback rattlesnake (Crotalus atrox) venom: isolation and characterization of five toxins and the role of zinc in hemorrhagic toxin e

1978 • 271 citations

Amino acid sequence of mouse nidogen, a multidomain basement membrane protein with binding activity for laminin, collagen IV and cells.

1989 • 230 citations

Purification and characterization of a rabbit bone metalloproteinase that degrades proteoglycan and other connective-tissue components

1983 • 222 citations

Localization of binding sites for laminin, heparan sulfate proteoglycan and fibronectin on basement membrane (type IV) collagen

1986 • 216 citations

Interactions of basement membrane components

1983 • 200 citations

Purification and characterization of a bone metalloproteinase that degrades gelatin and types IV and V collagen

1985 • 195 citations

Purification and properties of a gelatin-specific neutral protease from human skin.

1981 • 169 citations

Amino acid sequence of a Crotalus atrox venom metalloproteinase which cleaves type IV collagen and gelatin

1989 • 152 citations

Hemorrhagic toxins from rattlesnake (Crotalus atrox) venom. Pathogenesis of hemorrhage induced by three purified toxins.

1978 • 152 citations

Purification and Substrate Specificity of a Strongly Hydrophobic Extracellular Metalloendopeptidase (“Gelatinase”) from Streptococcus faecalis (Strain 0G1-10)

1989 • 148 citations

Hemorrhagic Toxins from Snake Venoms

1988 • 142 citations

Identification and interaction repertoire of large forms of the basement membrane protein nidogen.

1985 • 139 citations

Metalloproteinases from rabbit bone culture medium degrade types IV and V collagens, laminin and fibronectin

1981 • 138 citations

Transient expression of type IV collagenolytic metalloproteinase by human mononuclear phagocytes.

1986 • 122 citations

Characterization of Pepsin Fragments of Basement Membrane Collagen Obtained from a Mouse Tumor

1979 • 122 citations

Recessive dystrophic epidermolysis bullosa. Evidence for increased collagenase as a genetic characteristic in cell culture.

1978 • 121 citations

Fibronectin's amino-terminal matrix assembly site is located within the 29-kDa amino-terminal domain containing five type I repeats.

1988 • 108 citations

Characterization of proteolytic fragments of the laminin‐nidogen complex and their activity in ligand‐binding assays

1988 • 104 citations

Proteolytic specificity and cobalt exchange of hemorrhagic toxin e, a zinc protease isolated from the venom of the western diamondback rattlesnake (Crotalus atrox)

1983 • 79 citations

Collagenase in Normal and Pathological Connective Tissues

1980 • 74 citations

Substrate specificities and inhibition of two hemorrhagic zinc proteases Ht-c and Ht-d from Crotalus atrox venom

1986 • 73 citations

Collagenase in Human Cornea

1980 • 71 citations

Characterization of two hemorrhagic zinc proteinases, toxin c and toxin d, from western diamondback rattlesnake (Crotalus atrox) venom

1987 • 38 citations

Purification of a Gelatin-Degrading Type IV Collagenase Secreted by ras Oncogene-Transformed Fibroblasts

1988 • 38 citations

Analysis of the assembly of laminin and the laminin-entactin complex with laminin chain specific monoclonal and polyclonal antibodies

1988 • 35 citations

Further purification and some properties of a gelatin-specific proteinase of human leucocytes

1982 • 19 citations